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Copyright © The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.

KEEMU ET AL.

NOVEL BIOMARKERS FOR DIAGNOSING PROSTHETIC JOINT INFECTION FROM SYNOVIAL FLUID AND SERUM

http://dx.doi.org/10.2106/JBJS.OA.20.00067 Page 1

The following content was supplied by the authors as supporting material and has not been copy-edited or verified by JBJS.

Supplementary data 1. Box plots of eight natural log-transformed synovial biomarkers concentrations in PJI group compared to the control group. The biomarkers for these additional analyses were chosen based on Figure 1.

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Copyright © The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.

KEEMU ET AL.

NOVEL BIOMARKERS FOR DIAGNOSING PROSTHETIC JOINT INFECTION FROM SYNOVIAL FLUID AND SERUM

http://dx.doi.org/10.2106/JBJS.OA.20.00067 Page 2

Supplementary data 2. Box plots of seven natural log-transformed serum biomarkers concentrations in PJI group compared to the control group. The biomarkers for these additional analyses were chosen based on Figure 1.

(3)

Copyright © The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.

KEEMU ET AL.

NOVEL BIOMARKERS FOR DIAGNOSING PROSTHETIC JOINT INFECTION FROM SYNOVIAL FLUID AND SERUM

http://dx.doi.org/10.2106/JBJS.OA.20.00067 Page 3

Supplementary data 3. Area Under Curve (AUC) and P-values for biomarkers reaching

(4)

Copyright © The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.

KEEMU ET AL.

NOVEL BIOMARKERS FOR DIAGNOSING PROSTHETIC JOINT INFECTION FROM SYNOVIAL FLUID AND SERUM

http://dx.doi.org/10.2106/JBJS.OA.20.00067 Page 4

Supplementary data 4. Receiving operating characteristic curves (ROC) for eight additional synovial biomarkers.

(5)

Copyright © The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.

KEEMU ET AL.

NOVEL BIOMARKERS FOR DIAGNOSING PROSTHETIC JOINT INFECTION FROM SYNOVIAL FLUID AND SERUM

http://dx.doi.org/10.2106/JBJS.OA.20.00067 Page 5

Supplementary data 5. Receiving operating characteristic curves (ROC) for seven additional serum biomarkers.

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