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Supplementary Table 2 (table s2). Comparison of baseline characteristics between treated and untreated patients in the total sample and in the propensity score (PS) matched sample

Total sample PS-Matched sample

No ECT ECT No ECT ECT

Total 366,949 8,486 8,486 8,486

Women (n(%)) 202,125(55.1) 4,937(58.2) 4,852 (57.2) 4,937(58.2)

Mean age (years) 45.8 52.9 53.2 52.9

Only completed basic education (n(%)) 155,225(42.3) 2,811(33.1) 2,746(32.3) 2,811(33.1)

Married 123,939 (33.8) 4,331(51,0) 4,330(51.0) 4,331(51.0)

Diagnosis at first hospital contact

Dementia/delirium (n(%)) 56,125(15.4) 375(4.4) 384(4.5) 375(4.4)

Alcohol or drug abuse (n(%)) 22,073(6.1) 62(0.7) 233(2.8) 62(0.7)

Schizophrenia and psychotic disorders (n(%)) 12,801(3.5) 567(6.7) 445 (5.2) 567(6.7)

Mania/bipolar disorder (n(%)) 4,460(1.2) 849(10.0) 358(4.2) 849(10.0)

Depression without psychotic symptoms (n(%)) 62,987(17.3) 4,146(48.9) 3,857(45.5) 4,146(48.9) Depression with psychotic symptoms (n(%)) 1,852(0.5) 1,980(23.2) 740(8.7) 1,980(23.2)

Other affective disorders (n(%)) 2,079(0.6) 39(0.46) 35(0.4) 39(0.46)

Anxiety disorders (n(%)) 32,348(8.9) 77(0.9) 290(3.4) 77(0.9)

Adjustment disorders (n(%)) 80,550(22.1) 191(2.3) 1,041(12,3) 191(2.3)

Eating, sleeping, sexual disorders (n(%)) 11,208(3.1) 13(0.2) 47(0.6) 13(0.2)

Personality disorders (n(%)) 13,484(3.7) 89(0.2) 100(1.2) 89(0.2)

Mental retardation/developmental (n(%)) 4,798(1.3) 9(0.1) 9(0.12) 9(0.1)

Other mental disorders (n(%)) 17,767(4.9) 27(0.3) 341(4.0) 27(0.3)

Other contact codes (n(%)) 42,597(11.7) 0.62(0.7) 502(7.1) 0.62(0.7)

Region

Capital 116,663(31.8) 2,767(32.6) 2,794(32.9) 2,767(32.6)

Zealand 48,268(13.2) 872(10.3) 846(10.0) 872(10.3)

Southern Denmark 71,329(19.4) 1,321(15.6) 1,307(15.4) 1,321(15.6)

Central Denmark 101,419(27.6) 2,708(31.9) 2,753(32.4) 2,708(31.9)

Northern Denmark 29,270(7.9) 818(9.6) 786(9.3) 818(9.6)

Patient status (n(%))

Inpatient 39,364(10.7) 3,061(36.1) 3,065 (36.1) 3,061(36.1)

Outpatient 258,299(70.4) 3,049(35.9) 3,088(36.4) 3,049(35.9)

Emergency contact 69,287(18.9) 2,376(28.0) 2,333(27,5) 2,376(28.0)

Comorbidity (n(%))

Heart disease 21,083(5.8) 549(6.5) 524(6.2) 549(6.5)

Stroke 18,440(5.0) 446(5.3) 409(4.8) 446(5.3)

Diabetes 10,709(2.9) 268(3.2) 247(2.9) 268(3.2)

Epilepsia 9,868(2.7) 163(1.9) 125(1.5) 163(1.9)

Previous traffic accident

Medication <1year before inclusion (n(%)) 75,491(20.6) 1,442(17.0) 1,433(16.9) 1,442(17.0)

Tricyclic antidepressants (TCA) 10,980(3.0) 640(7.5) 591(7.0) 640(7.5)

Antipsychotics 41,281(11.3) 1,551(18.3) 1,477(17.4) 1,551(18.3)

Antiparkinsonian drugs 2,417(0.7) 67 (0.8) 75(0.9) 67 (0.8)

Hypnotics 58,624(16.0) 2,943(34.6) 2,938(34.6) 2,943(34.6)

Anxiolytics 58,987(16.1) 2,835(33.4) 2,803(33.0) 2,835(33.4)

Antiepileptic drugs 22,104(6.0) 686(8.1) 689(8.1) 686(8.1)

Opioids 13,415(3.7) 410(4.8) 436(5.2) 410(4.8)

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