https://links.lww.com/SCS/C884

Table Supplemental 1. Primary characteristics of radiation to osteoradionecrosis.

Case

Gende r/Age

Site/

Histology Therapy

Delivery techniqu

es

Dose

(Gy) Hypert

ension Coronary

disease Diabetes Time (RT to ORN, mo)

LENT-

SOMA VAS “BS”

classifica tion

1 F/31 Palate/SCC Surgery + RT

Con-RT

70 NO NO NO 6 2 4

B2S1

2 M/50 Mouth

floor/SCC Surgery + RT IMRT 110 NO NO NO 36 1 2

B2S1

3 M/63 Mouth

floor/SCC Surgery + RT

Con-RT

60 NO YES NO 3 2 8

B2S2

4 M/38 Gingival/

Melanoma RT IMRT 110 NO NO NO 12 2 1

B2S2

5 F/54 Tongue/SC

C Surgery +RT

& CT IMRT 130 YES NO NO 24 3 3

B2S2

6 F/59 Neck/

Lymphoma RT IMRT 60 YES NO YES 84 2 6

B2S1

7 M/38 Oropharynx /Lymphom

a

RT IMRT 110 NO NO NO 120 3 6

B2S2

8 M/43 Tonsil/SCC RT IMRT 120 NO NO NO 48 3 7

B2S1

9 M/58 Tonsil/SCC RT & CT

Con-RT

70 NO NO NO 60 3 6

B3S2

10 F/58 NPC RT IMRT 70 YES NO NO 48 1 2

B2S0

11 F/47 NPC RT & CT IMRT 158 NO NO NO 192 3 7

B2S2

12 F/48 NPC RT & CT IMRT 120 NO NO NO 36 2 3

B2S2

13 F/63 NPC RT & CT IMRT 76 NO NO NO 72 3 8

B3S1

14 M/58 NPC RT IMRT 74.6 NO NO NO 12 3 6

B2S1

15 M/56 NPC RT IMRT 138 YES NO NO 36 2 1

B2S2

16 M/76 NPC RT IMRT 76.8 NO NO NO 96 2 4

B3S2

17 M/39 NPC RT

Con-RT

110 NO NO NO 48 3 7

B3S2

18 M/56 NPC RT IMRT 129 NO NO NO 120 2 2

B2S1

19 M/52 NPC RT IMRT 130 NO NO NO 84 3 5

B2S1

20 F/49 NPC RT IMRT 130 NO NO NO 120 3 7

B2S2

21 F/47 NPC RT IMRT 60 NO NO NO 60 3 7

B3S1

22 M/49 NPC RT IMRT 70 NO NO NO 24 3 8

B3S2 Abbreviations: F, female; M, male; ORN, osteoradionecrosis; RT, radiotherapy; + = consecutive; & = combined; SCC, squamous cell carcinoma;

NPC, nasopharyngeal carcinoma; Con-RT, conventional radiotherapy;

IMRT, intensity-modulated radiotherapy

; RT to ORN, time from termination of

radiation to osteoradionecrosis