Lahiri et al Results _AoS.pptx

Pre-operative

0 2000 4000 6000

0 500 1000 1500

TLR4

LPS-induced IL-6

Pre-operative

0 2000 4000 6000

0 200 400 600

TLR5

Flagellin-induced IL-6

Day 1

0 2000 4000 6000 8000

0 500 1000 1500

TLR4

LPS-induced IL-6

Day 1

0 2000 4000 6000 8000

0 200 400 600

TLR5

Flagellin-induced IL-6

Day 2

0 2000 4000 6000 8000

0 1000 2000 3000 4000

TLR4

LPS-induced IL-6

Day 2

0 2000 4000 6000 8000

0 1000 2000 3000 4000 5000

TLR5

Flagellin-induced IL-6

Supplemental  Digital  Content  5.  TLR  expression  and  TLR-­‐mediated  cytokine  produc=on  are   closely  correlated.    Correla'on  between  the  pre-­‐opera've,  day  1  and  day  2  expression  of   TLR4  and  LPS-­‐s'mulated  IL-­‐6  produc'on  (A-­‐C)  or  TLR5  and  flagellin-­‐s'mulated  IL-­‐6  produc'on   (D-­‐F)  in  pa'ents  who  have  an  unevenJul  recovery  (closed  circles)  and  those  who  develop  SIRS   (open  circles).  The  r²  coefficient  is  presented  with  each  graph  –  need  to  add.    p<0.0001  for  all   correla'ons.  

 

r²=0.55  

r²=0.41  

r²=0.64  

r²=0.79  

r²=0.74  

r²=0.69  

A   B   C  

D   E   F