Figure S1. Characteristics of the 2 larger clusters: cluster 1 (CRF02_AG; n=11) and cluster 29 (B; n=6). Transmission network and dates of diagnosis for each case (1 square per case).
The estimated TMRCA is indicated. Maps represent the location of residence of the clustering individuals. Legend for the color codes is shown at the bottom.
Table S1. Data collected in the anonymous HIV case reporting system.
Variables Type Coding
Sociodemographic variables
Sex qualitative Male
Female
Age at diagnosis quantitativ
e In years
Department of residence qualitative Number of department Department of laboratory qualitative Number of department
Professional categories qualitative
Farmers
Artisans, merchants and business managers
Higher intellectual professions Intermediate professions Employees
Workers Unemployed
Country of birth qualitative
France North Africa Sub-saharan Africa Other European country Others (Asia, America) Country of HIV infection qualitative France
Foreign Professional activity (at time of
diagnosis) qualitative Yes
No
Type of declaring laboratory qualitative Private laboratory in town Hospital
Type of declaring Physician qualitative Medical professional activity in town Hospital
Clinical and biological variables
Date of diagnosis date mm/dd/yyyy
Transmission category qualitative
Heterosexual MSM
Intravenous drug user Other
Clinical stage qualitative
Primary infection Asymptomatic
Symptomatic non-AIDS AIDS
Motive of screening qualitative
Clinical or biological signs Recent exposure to HIV
Supported for another pathology Medical check-up
Organized screening Other
Serology at the initiative of qualitative Physician Patient
Presence of HBV infection (HBs
Ag) qualitative yes
no Presence of HCV infection qualitative yes
no Presence of sexually transmitted
infection qualitative yes
no
Table S2 : Comparative analysis of populations included in clusters and not included.
Qualitative variable Cluster Non-
cluster Univariable Multivariable
n % n % p OR 95IC p
Sex
0.035
Female 5 4.67 51 11.54 1
Male 102 95.3
3 391 88.46 1.2 [0.2 - 7.8] 0.82
Transmission category
<0.0001
Others 5 6.67 108 30.59 1
MSM 70 93.3
3 245 69.41 3.8 [1.1 - 12.9] 0.03
Country of birth
0.015
France 66 94.2
9 284 82.8 1
Foreign 4 5.71 59 17.2 0.4 [0.14 - 1.26] 0.12
Subtype
0.964
B 69 64.4
9 284 64.25 . . .
Non-B 38 35.5
1 158 35.75 . . .
Serology at the initiative of
0.218
Physician 39 72.2
2 228 79.72 . . .
Patient 15 27.7
8 58 20.28 . . .
Clinical stage
0.721 Primary HIV infection 54 72.9
7 262 73.8 . . .
Asymptomatic 19 25.6
8 83 23.38 . . .
Symptomatic non-AIDS 1 1.35 10 2.82 . . .
Region of residence
0.473
Paris area 35 36.4
6 163 40.45 . . .
Other 61 63.5
4 240 59.55 . . .
Quantitative variable Mean Mean p OR 95IC P
Age at diagnosis 33.9 38.6 0.0001 0.9
8 [0.95 - 1.0] 0.07
