Supplemental
Table 2. Univariable risk factor analysis for condomless sex acts in the past 30 days. TDF2 clinical trial, Botswana 2007-2010.
Characteristic No condomless sex acts ≥1 condomless sex acts Odds
Ratio 95% CI p-value Rate
Ratio 95% CI p-value Time (per year) 1.16 1.05, 1.28 0.0042 1.04 0.95, 1.14 0.3683 Treatment
TDF 0.84 0.64, 1.11 0.2182 1.09 0.88, 1.34 0.4457
Placebo REF REF
Treatment Arm Perception
TDF 1.06 0.78, 1.44 .7013 0.90 0.70, 1.17 0.4371
Not Sure 1.00 0.77, 1.31 .9685 0.86 0.69, 1.09 0.2167
Placebo REF REF
Age
18-20 REF REF
21-29 0.92 0.35, 2.46 0.8696 0.98 0.45, 2.12 0.9595
30+ 0.72 0.25, 2.08 0.5387 1.57 0.68, 3.63 0.2873
Gender
Female REF REF
Male 1.08 0.82, 1.42 .5916 1.17 .95, 1.45 0.1471
Education
Primary or less REF REF
Secondary 1.31 0.62, 2.80 0.4785 0.95 0.53, 1.71 0.8664 Postsecondary 0.81 0.37, 1.79 0.6041 1.24 0.68, 2.29 0.4837 Site
Francistown REF REF
Gaborone 1.04 0.79, 1.36 0.7965 1.03 0.83, 1.28 0.7876 Marital Status
Single REF REF
Married 0.70 0.39, 1.25 0.2238 1.26 0.82, 1.95 0.2890
Occupational Status
Employed 1.06 0.80, 1.40 0.7011 1.04 0.84, 1.29 0.7202
Unemployed REF REF
Sexual Debut
15 or less 0.38 .24, .61 <.0001 1.58 1.09, 2.27 .0153
16-17 0.48 .32, .71 0.0003 1.65 1.21, 2.26 .0018
18-19 0.71 .49, 1.02 .0621 1.27 0.95, 1.70 .1102
20+ REF REF
HIV Status
Positive 0.80 0.36, 1.79 0.5852 0.60 0.32, 1.14 0.1175
Negative REF REF
STI
Yes 0.49 0.31, 0.76 0.0015 0.79 0.56, 1.13 0.1930
No REF REF
HSV-2
Yes 0.80 0.60, 1.06 0.1228 1.30 1.05, 1.63 0.0178
No REF REF
