Supplementary Table 2. Univariate analysis of DLB patient baseline characteristics
Characteristic (N, %)
All DLB Patients (N = 269)
Demographics
Age in years (mean, SD) 72.5 (7.0)
60-64 38 (14.1%)
65-74 125 (46.5%)
75-84 95 (35.3%)
85-94 11 (4.1%)
95+ 0 (0.0%)
Female 60 (22.3%)
Race
White 237 (88.1%)
Black 21 (7.8%)
Other/unknown 11 (4.1%)
Hispanic 10 (3.7%)
Education level
High school or less 85 (31.6%)
College 97 (36.1%)
Graduate school 87 (32.3%)
Unknown 0 (0.0%)
Marital status
Married 236 (87.7%)
Widowed/divorced/separated 31 (11.5%)
Never married 1 (0.4%)
Other/unknown 1 (0.4%)
Living situation
Able to live independently 33 (12.3%)
Residence
Single family residence 228 (84.8%)
Retirement community 8 (3.0%)
Assisted living/boarding home 12 (4.5%)
Other/unknown 13 (4.8%)
Health history
Alcohol abuse 1 (0.4%)
B12 deficiency 9 (3.4%)
Brain trauma 7 (2.6%)
Congestive heart failure 5 (1.9%)
Cerebrovascular disease 40 (14.9%)
Diabetes 28 (10.4%)
Hypercholesterolemia 120 (44.6%)
Hypertension 108 (40.2%)
Incontinence 104 (38.7%)
Ischemic attack 3 (1.1%)
Seizures 1 (0.4%)
Stroke 8 (3.0%)
Thyroid disease 23 (8.6%)
Global CDR score
0.5 88 (32.7%)
1 128 (47.6%)
2 41 (15.2%)
3 12 (4.5%)
Drug use
Anxiolytic, sedative, or hypnotic agent 78 (29.0%)
Antidepressant 111 (41.3%)
Medication for AD symptoms 183 (68.0%)
Antiparkinson agent 66 (24.5%)
Antipsychotic agent 47 (17.5%)
[1] Characteristics assessed using each patient's first visit with a DLB diagnosis. DLB diagnosis is defined as a visit with a primary or contributing etiologic diagnosis of DLB
[2] Cognitive symptoms are defined as the presence of cognitive fluctuations.
[3] Neuropsychiatric symptoms are defined as the presence of delusions in the last month or the manifestation of visual hallucinations.
[4] Sleep symptoms are defined as the presence of REM Behavioral Disorder (RBD [5] Motor symptoms are defined as the presence of parkinsonian signs or parkinsonian gait.
[6] Functional activities questionnaire score was calculated as the number of functional activities the subject had difficulty completing. Score ranges from 0 to 10.
[7] NPI-12 score was calculated as number of neuropsychiatric symptoms reported by the patient or caregiver. Score ranges from 0 to 12.
[8] Statistical significance calculated relative to the DLB patients with a primary diagnosis using Fisher's exact test for categorical variables and the Wilcoxon rank-sum test for continuous variables.
