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Supplemental Digital Content 11

Boxplots of Shannon diversity values calculated from log normalized OTU abundances from the cecal content samples and the Benjamini-Hochberg corrected p-values of the statistical models.

This includes Wilcoxon tests on stress and sex terms and the terms for the mixed linear model.

All p-values are Benjamini-Hochberg FDR corrected with each term in the model corrected separately.

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Control Experimental

5.96.1

Wilcoxon Stress p−value 0.651

Shannon diversity

female male

5.96.1

Wilcoxon Sex p−value 0.0348

Shannon diversity

Shannon diversity at level 1

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Control Experimental

5.96.1

Stress p−value 0.41

Shannon diversity

● ●

female male

5.96.1

Sex

p−value 0.000452

Shannon diversity

Shannon diversity at level 1

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5.96.1

Stress*Sex interaction p−value 0.0822

Shannon diversity

Control Female

Stress Female

Control Male

Stress Male

5.9 6.0 6.1 6.2

Cage effect p−value 0.162

Shannon diversity

CF1 CF2 SF1 SF2 CM1 CM2 SM1 SM2

Shannon diversity at level 1

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