Supplemental Digital Content 3. Diagnoses at Time of Hospitalization during AD Transitions*
Alzheim er’s Dis- ease Only
Dementia with Suspected Etiology to Alzheimer’s
Disease
Dementia with No
Known Cause to Alzheimer’s
Disease
Cognitive Disturb- ance not Demented
to Alz- heimer’s
Disease
Cognitive Disturbance
to Demen- tia with No
Known Cause to Alzheimer’s
Disease
Total Cohort (N) 23,580 2,241 7,218 16,931 4,642
Hospitalized during AD Transition 9,901 1,064 2,941 7,267 1,956
% Hospitalized during AD
Transition 42.0% 47.5% 40.8% 42.9% 42.1%
Medicare Per-Person Hospital
Payments during AD Transition $1,133 $1,406 $1,156 $1,291 $1,214 Diagnostic Area (3-digit ICD-9
code) % of Hospitalizations during AD Transition
Cerebral Degeneration† (331) 7.2% 4.6% 5.1% 6.0% 5.0%
Pneumonia Organism NOS (486) 6.2% 8.2% 7.7% 6.8% 8.0%
Fluid/Electrolyte Disorders (276) 6.0% 6.0% 5.7% 5.9% 6.1%
Fractured Neck of Femur (820) 6.0% 6.9% 8.1% 6.2% 6.3%
Heart Failure (428) 5.8% 6.5% 5.4% 6.4% 6.3%
General Symptoms‡ (780) 5.2% 5.1% 6.8% 6.8% 6.3%
Other Urinary Tract Disorders
(599) 4.4% 7.0% 6.1% 6.3% 6.6%
Cardiac Dysrhythmias (427) 4.3% 4.4% 3.8% 4.2% 4.0%
Cerebral Artery Occlusion (434) 3.8% 3.9% 3.3% 4.1% 3.6%
Acute Myocardial Infarction (410) 3.6% 3.5% 3.4% 3.0% 2.8%
Septicemia (038) 2.8% 5.6% 4.0% 3.4% 4.8%
Transient Cerebral Ischemia (435) 2.6% 2.3% 1.9% 2.4% 2.6%
Other Chronic Ischemic Heart
Disease (414) 2.2% 1.6% 1.7% 1.8% 1.5%
Chronic Bronchitis (491) 2.0% 2.3% 1.8% 1.9% 2.5%
Respiratory System/Other Chest
Symptoms (786) 1.9% 1.6% 1.8% 2.2% 2.6%
Acute Renal Failure (584) 1.8% 2.3% 2.2% 2.5% 3.0%
Diabetes Mellitus (250) 1.7% 1.3% 2.0% 2.2% 2.0%
Solid/Liquid Pneumonitis (507) 1.7% 3.7% 3.0% 2.4% 2.9%
Other Cellulitis/Abscess (682) 1.4% 1.5% 1.5% 1.5% 1.6%
Diverticula of Intestine (562) 1.3% 0.9% 1.5% 1.2% 1.0%
*For this analysis, transition months include the month prior through month after the AD diagnosis
†Principally Alzheimer’s disease (331.0)
‡Principally syncope and collapse (780.2), convulsions not elsewhere classified (780.39), and other neurologic conditions
NOS = not otherwise specified
