1 Supplemental Tables:
Table S1: Number (N) of asymptomatic participants who tested positive using the SD Bioline and Syphilis Health Check tests with sensitivity and specificity compared to the TPHA and TPHA+RPR reference standards.
SD Bioline TPHA Syphilis
Health Check
TPHA
Reactive Non reactive
Total Reactive Non
Reactive
Total
Positive 52 8 60 Positive 50 4 54
Negative 3 4 7 Negative 5 8 13
Total 55 12 67 Total 55 12 67
Sensitivity 94.5(84.9-98.9) Sensitivity 90.9(80.0-96.9) Specificity 33.3(9.9-65.1) Specificity 66.7(34.9-90.1)
SD Bioline RPR+TPHA Syphilis
Health Check
RPR+TPHA
Reactive Non reactive
Total Reactive Non
Reactive
Total
Positive 47 2 49 Positive 45 0 45
Negative 1 4 5 Negative 3 6 9
Total 48 6 54 Total 48 6 54
Sensitivity 97.9(88.9-99.9) Sensitivity 93.7(82.8-98.7) Specificity 66.7(22.3-95.7) Specificity 100(54.1-100)
2
Table S1: Number (N) of symptomatic participants who tested positive using the SD Bioline and Syphilis Health Check tests with sensitivity and specificity compared to the TPHA and TPHA+RPR reference standards.
SD Bioline TPHA Syphilis
Health Check
TPHA
Reactive Non reactive
Total Reactive Non
Reactive
Total
Positive 38 12 50 Positive 38 5 43
Negative 5 93 98 Negative 5 100 105
Total 43 105 148 Total 43 105 148
Sensitivity 88.4(74.9-96.1) Sensitivity 88.4(74.9-96.1) Specificity 88.6(80.9-93.9) Specificity 95.2(89.2-98.4)
SD Bioline RPR+TPHA Syphilis
Health Check
RPR+TPHA
Reactive Non reactive
Total Reactive Non
Reactive
Total
Positive 37 7 44 Positive 36 2 38
Negative 0 92 92 Negative 1 97 98
Total 37 99 136 Total 37 99 136
Sensitivity 100.0(90.5-100.0) Sensitivity 97.3(85.8-99.9) Specificity 92.9(85.9-97.1) Specificity 97.9(92.9-99.7)
