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1 Supplementary Table 1. Association of serum phosphorus levels at 1 year after renal transplantation and covariates with death with a functioning graft Parameters Univariate Multivariate HR (95% CI) P-value HR (95% CI) P-value

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Supplementary Table 1. Association of serum phosphorus levels at 1 year after renal transplantation and covariates with death with a functioning graft

Parameters Univariate Multivariate

HR (95% CI) P-value HR (95% CI) P-valuea Serum phosphorus

< 2.5 mg/dL (lowest) 2.5-2.99 mg/dL 3.0-3.49 mg/dL 3.5-3.99 mg/dL 4.0-4.49 mg/dL 4.5-4.99 mg/dL ≥ 5.0 mg/dL (highest)

6.67 (1.94-22.91) 2.23 (0.71-7.05) 2.59 (1.03-6.48) 1.0 (reference) 1.73 (0.63-4.76) 1.68 (0.43-6.50) 4.70 (1.21-18.16)

0.003 0.17 0.04

0.29 0.45 0.03

9.32 (2.26-38.34) 3.10 (0.81-11.83) 3.23 (0.98-10.64) 1.0 (reference) 2.53 (0.75-8.51) 1.74 (0.31-9.62) 5.30 (0.88-31.94)

0.002 0.10 0.06

0.13 0.53 0.07 Age (per 1 year)

Male (vs. female)

Living donor (vs. deceased) Donor age (per 1 year) Diabetes (vs. none)

eGFR (per 1 mL/min/per 1.73m2)

Albumin (per 1 g/dL) BMI (per 1 kg/m2) Hemoglobin (per 1 g/dL) T.Chol (per 1 mg/dL)

1.08 (1.05-1.11) 1.14 (0.61-2.12) 0.46 (0.25-0.85) 1.02 (0.98-1.04) 2.56 (1.40-4.68) 0.99 (0.97-1.01)

0.25 (0.17-0.38) 1.05 (0.95-1.16) 0.83 (0.71-0.96) 0.99 (0.98-1.01)

<0.001 0.68 0.01 0.26 0.002

0.18

<0.001 0.32 0.01 0.35

1.07 (1.03-1.10) 1.21 (0.57-2.60) 0.70 (0.33-1.47) 1.02 (0.98-1.05) 1.22 (0.59-2.52) 1.01 (0.99-1.03)

0.50 (0.24-1.03) 0.98 (0.87-1.10) 0.92 (0.75-1.12) 1.00 (0.99-1.01)

<0.001 0.62 0.35 0.33 0.60 0.54

0.06 0.75 0.41 0.78 Supplemental material is neither peer-reviewed nor thoroughly edited by CJASN. The authors alone are responsible for the accuracy and presentation of the material.

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Acute rejection (vs. none) 1.94 (1.05-3.57) 0.03 1.51 (0.73-3.11) 0.27

a Multivariate Cox proportional hazard ratios, adjusted for recipient age and sex, donor type, donor age, diabetes mellitus, body mass index, acute rejection, and estimated glomerular filtration rate, serum albumin, hemoglobin, total cholesterol levels at 1 year after transplantation.

The study population was classified into 7 groups according to the level of serum phosphorus at 1 year after transplantation with intervals of 0.5 mg/dL (lowest group, < 2.5 mg/dL; highest group, ≥ 5.0 mg/dL; reference group, 3.5-3.99 mg/dL).

Abbreviations: HR, hazard ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; BMI, body mass index; T.Chol, total cholesterol.

Supplemental material is neither peer-reviewed nor thoroughly edited by CJASN. The authors alone are responsible for the accuracy and presentation of the material.

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3 Supplementary Figure 1

Supplemental material is neither peer-reviewed nor thoroughly edited by CJASN. The authors alone are responsible for the accuracy and presentation of the material.

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