Supplementary Figure 1 - http;//links.lww.com

Supplementary Figure 1

Silencing PPARA promoted cell viability and proliferation of ARPE-19

(A) CCK8-assay for the detection of the viability of ARPE-19 transfected with sh-NC or sh-PPARA.

(B) Cell proliferation was detected, via BrdU assay, in ARPE cells transfected with sh-NC or sh-PPARA. *, P< 0.05; **, P< 0.001; sh-NC, sh-PPARA negative control; sh-PPARA, shRNA of PPARA.

Supplementary Table 1 The sequences of mimic, inhibitor, NC and shRNA in this study Sequences

miR-657 mimic Forward:5’-GGCAGGUUCUCACCCUCUCUAGG-3’

Reverse:5’-UAGAGAGGGUGAGAACCUGCCUU-3’

mimic-NC Forward:5’-UUCUCCGAACGUGUCACGUTT-3’

Reverse:5’-ACGUGACACGUUCGGAGAATT-3’

miR-657 inhibitor 5’-CCUGGAGAAGCGUGGACCGGUCC-3’

inhibitor-NC 5’-GAUGUUGAAACAUCAGUCUGA-3’

sh-PPARA 5’-CGAUCAAGUGACAUUGCUAAA-3’

sh-NC 5’-GTCAATGGTCGTGTCGTGC-3’