S1 Table: Brain Derived Neurotrophic Factor in association with symptoms and diagnosis at hospital admission
with platelet count as a covariate.
Clinical Variable Present n (%)
Absent n (%)
OR (95%CI)
P-value aOR (95% CI)
P-value
Coma 57 (32) 122 (68) 0.80 (0.69, 0.93) 0.004 0.82 (0.71, 0.95) 0.009 Cerebral Malaria 79 (44) 100 (56) 0.79 (0.66, 0.94) 0.007 0.83 (0.70, 0.98) 0.028 LODS >1 46 (26) 133 (74) 0.86 (0.76, 0.98) 0.019 0.82 (0.72, 0.95) 0.006 Respiratory Distress 79 (44) 100 (56) 0.85 (0.75, 0.98) 0.022 0.83 (0.72, 0.96) 0.014 Death or Disability 29 (16) 150 (84) 0.70 (0.49, 0.98) 0.04 0.71 (0.50, 1.00) 0.05 Prostration 16 (9) 164 (91) 0.84 (0.73, 0.97) 0.018 0.84 (0.72, 0.97) 0.02 Shock 16 (9) 163 (91) 0.63 (0.37, 1.06) 0.083 0.47 (0.24, 0.94) 0.033 Convulsions 36 (20) 143 (80) 1.01 (0.88, 1.18) 0.85 1.04 (0.89, 1.21) 0.64 Jaundice 28 (16) 150 (84) 0.90 (0.74, 1.11) 0.34 0.84 (0.66, 1.06) 0.13 Hemoglobinuria 33 (18) 147 (82) 0.84 (0.69, 1.02) 0.063 0.86 (0.65, 0.99) 0.05 Lambaréné Organ Dysfunction Score (LODS).
