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Identification of PKC-directed ligands from different sources

3.6 Appendix I

Full list of selected plants for study

Table 3.7: List of 50 medicinal plants explored for therapeutic phytochemicals

S No. Botanical Name Common Name Ethnobotanical uses

1. Camellia sinensis Tea Used as a beverage. Also used as a carminative, CNS stimulant and also possess anti-cancer property.

2. Coffea arabica L Coffee Used as a beverage. Also used as a cardiotonic, CNS stimulant, treatment of asthma and headache.

3. Curcuma longa Indian Saffron;

Turmeric

Key spice of many South Asian and Middle Eastern cooking. Extracts from turmeric have antifungal and antibacterial properties.

4. Curcuma xanthorrhiza Temu Lawak; Javan Turmeric

It is used as a spice. Useful for treating digestive disorders and anti-inflammation.

5. Zingiber officinale Ginger Used as a spice. It is used to treat digestive disorders, treatment of fever, nausea and vomiting and possess anti-microbial property.

6. Capsicum annuum Paprika; Green Pepper; Cherry Pepper; Bell Pepper;

Cone Pepper; Sweet Pepper

Used as a spice. It is used in combination of homeopathic and natural preparations. It is used as a relief of oral discomfort or toothache, external analgesia, as a digestive aid, in menstrual conditions, and in cosmetics as cleansers and bath products.

7. Capsicum frutescens Cayenne; Chilli;

Tabasco; Hot Pepper;

Spur Pepper; Red Chili

Similar use as Capsicum annuum.

Chapter 3|97 8. Pisum sativum Pea Used as food.It is recommended for heart

diseases, diabetes and nervous system disorders.

9. Hibiscus sabdariffa Roselle; Oseille De Guinee; Vinagrillo;

Maravilla; Kerkedeh;

Chai Kujarat; Afrika Bamyasi

Used as a flavouring agent. Also used to lower pressure in hypertension.

10. Nicotiana tabacum Tabigh; Tobacco;

Tabaco

Used for curing toothache, antidote to bee- sting, centipede bites,scorpion-bites. Used in asthma. Used as Parasiticide, anti-cancer agent and CNS stimulant.

11. Uncaria tomentosa Cats Claw Reduce pain and inflammation of rheumatism, arthritis and other types of inflammatory problems. Has anti-tumor and anti-cancer properties and is useful for treatment of gastric ulcers and intestinal complaint.

12. Uncaria catechu khoyer Catechu is used for diarrhea, swelling of the nose and throat, dysentery, swelling of the colon (colitis), bleeding, indigestion, osteoarthritis, and cancer. Also used for treatment of skin-diseases.

13. Sophora pachycarpa Kowhai Possess anti-bacterial and anti-allergic properties. Considered as a potential chemotherapeutic agent in cancer treatment.

14. Syringa vulgaris Lilac Used in homeopathy. Also used to treat fever and malaria.

15. Citrus limon Lemun Tresh;

Limonero; Lemun Hamedh; Lemon;

Miski; Limon

Used to treat cold, fever, inflammation, diarrhoea, dysentery and digestive disorders.

16. Allium sativum Garlic Used to cure any kind of ache in the body.

Used as antiseptic, antidote, arthritis, asthma, bronchitis, malaria, as a vasodilator and most importantly in the treatment of cancer.

17. Brassica napus var.

napobrassica

Turnip; Naveterinary;

Nabo

Used bin the treatment of cold, gout and as anti-cancer agent.

18. Triticum aestivum Common wheat Known to be used to treat fever and diarrhoea.

19. Aloe vera Djadam arab; Jadam;

Nu Hui

Treatment of fever, cough, asthma and cancer.

20. Eupatorium perfoliatum Eupatorio; Indian Sage; Hempweed

Used in the treatment of cough, cold, dengue, as a laxative and in malaria.

21. Arnica montana Arnica; Dagtutunu Used in the treatment of fever, as a cardiotonic and in the treatment of cancer.

22. Acacia nilotica Babli; Gumarabic Used as a Decongestant, treatment of gall- bladder, spleen and as an anti-cancer agent.

23. Artemisia annua Kuso-Ninzin; Huang Hua Hao

Used as bacteriocide, treatment of abscess, eye, fever, jaundice, skin-disease, stomach ache and dysentery.

24. Dionaea muscipula Venus' Fly Trap Used in the treatment of HIV, Crohn's disease and skin cancer.

25. Myroxylon balsamum Balsam Of Tolu Used as an antibacterial and antiseptic.

26. Illicium verum Pa Chio Yu Used as diuretic, antiseptic, in the treatment of dyspepsia, constipation and dysentery.

27. Ocimum basilicum Great basil; Saint- Joseph's-wort

Used to cure ache (ear, head, tooth, stomach), antidote, as a carminative, treatment of kidney diseases, nausea, gout, sinus, spasm and possess anti-cancer properties.

28. Coccinia grandis Ivy gourd Used to treat leprosy, fever, asthma, bronchitis, and jaundice. Possesses mast cell-stabilizing, antianaphylactic, and antihistaminic potential. Used in the treatment of scabies.

29. Lawsonia inermis Henna, Jetuka Used tro treat stomach ache, headache, as an astringent, bacteriocide, fungicide, as hair-dye and treatment of inflammation and jaundice.

30. Berberis vulgaris Agracejo; Epine Vinette; Amberparis

Used as antiseptic, diuretic, laxative and ion the treatment of jaundice, fever, dyspepsia and dysentery.

31. Eschscholzia californica

Khishkhash Kalifornia;

Kaliforniya Hashasi

Used as analgesic and soporific.

32. Mahonia aquifolium Oregongrape; Oregon Grape

Known to possess bactericidal preoperties.

33. Thymus vulgaris Common Thyme Used as antiseptic, carminative, in the treatment of bronchitis, cancer and digestive disorders.

34. Rheum officinale Huang Liang;

Kelembak; Chiang Chun

Used in the treatment of boil, burns, dysentery, diarrhoea and cancers of cervix and stomach.

35. Zanthoxylum americanum

Prickly Ash;

Ache(Tooth) Tree

Used in the treatment of rheumatism, cough, cold, colitis and gonorrhoea.

36. Podophyllum pleianthum

Mayapple Used as Cathartic, treatment of warts, rheumatoid arthritis, and possess anti- cancer properties.

37. Arctium lappa L Kewe; Bardana;

Waisar; Burdock;

Lampazo Mayor

Used as antidote, bactericide, carminative, treatment of cough and cold, fever, flu, gonorrhoea, gout, infection, measles, piles, pneumonia, tonsillitis, syphilis and cancer.

Chapter 3|99 38. Sorbus aucubaria L Rowan Tree; Serbal

Silvestre; Uvez Agaci;

European Mountainash

Used as an astringent, diuretic and in the treatment of gall-bladder, dyspepsia and rectal cancer.

39. Solanum tuberosum Potato Used mainly as a food. But also known to be used in the treatment of peptic ulcers rheumatic joints, swellings, skin rashes and haemorrhoids.

40. Lycopersicon esculentum

Tomato Primarily used as food. Also used as antiseptic, treatment of cough, cold, fever and for digestive disorders.

41. Vitis vinifera European Grape Used as astringent, expectorant, diuretic, laxative and in the treatment of cancer.

42. Glycyrrhiza glabra L. Madhuka; Licorice Used in the treatment of cough, cold, as antidote, diuretic, expectorant and treatment of cancer.

43. Thespesia populnea Grand Mahaut Treatment of headache, insect bites, cholera, cold, fever, scabies, stomachache, warts and dysentery.

44. Glycine max Soybean Used as food. Also used as antidote, laxative, treatment of burns, malaria and cancer.

45. Cephaelis ipecacuanha Altim Koku; Tokon Treatment of amebiasis, dysentery and cancer.

46. Artemisia vulgaris Sundamala Used as an aphrodisiac, antidote of snake bite, treatment of dysmenorrhea, digestive disorders and dysentery.

47. Mitragyna speciosa Bia; Ketum; Biak;

Kutum

Used in the treatment of fever

48. Echinacea angustifolia Coneflower Used as antiseptic, aphrodisiac, treatment of cough, cold and digestive disorders.

49. Chimaphila umbellata L

Pipsissewa;

Chimaphile; Spotted Wintergreen

Used in the treatment of diabetes, kidney disorders, fever and digestive problems.

50. Oryza sativa Asian rice Used mainly as a food. However it is also used as an antidote, diarrhoea and various bowel disorders.

Chapter 4

PKC-directed molecules affects breast cancer cells in

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