The Effect of High-Intensity Interval Training on Circulating Leptin Levels in Individuals With and Without Chronic Diseases: A Systematic Review and Meta-analysis

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The Effect of High-Intensity Interval Training on Circulating Leptin Levels in Individuals With and Without Chronic Diseases: A Systematic Review and

Meta-analysis

Mohammad Javad Pourvaghar¹^ , Saeed Reza Noori Mofrad² , Mousa Khalafi³

1. Corresponding Author, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran. E-mail: [email protected]

2. Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran. E-mail:

[email protected]

3. Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran. E-mail:

[email protected]

Article Info ABSTRACT

Article type:

Meta-analysis

Article history:

Received:

25 January 2023 Received in revised form:

24 April 2023 Accepted:

25 April 2023 Published online:

25 April 2023

Keywords:

Continuous Training, Interval Training, Leptin,

Obesity.

Introduction: This study aimed to investigate the effect of High-Intensity Interval Training (HIIT) on serum leptin levels in individuals with and without chronic diseases.

Methods: In this research, a systematic search was conducted in Persian and English articles published until December 2022, in Web of Science, Scopus, PubMed, SID, and Magiran databases using relevant keywords. After selecting the desired articles based on the inclusion criteria, a meta-analysis of the results was performed. Effect size (SMD) and 95% confidence interval were calculated using CMA2 software. The I² test was used to identify the heterogeneity, and for the publication bias, the Funnel Plot test and the Egger test were used. All analyzes were performed using CMA2 software.

Results: The results of data analysis showed that HIIT led to a significant decrease in serum leptin [-0.28 (CI: -0.07 to 0.48, p=0.008)]. Also, the data analysis of 9 interventions showed that there was no significant difference between HIIT and Medium Intensity Continuous Training (MICT) on circulating leptin levels [-0.03 (0.27 to 0.34 CI, p=0.82)]. The results of the subgroup analysis based on the health status of the subjects showed that HIIT resulted in a significant decrease in leptin in individuals with chronic diseases.

Conclusion: HIIT leads to a decrease in circulating leptin levels, especially in individuals with chronic diseases. Despite the lack of significant differences between HIIT and MICT, HIIT is a time-efficient intervention for leptin reduction.

Cite this article: Pourvaghar M.J., Noori Mofrad S.R., & Khalafi M. The Effect of High-Intensity Interval Training on Circulating Leptin Levels in Individuals With and Without Chronic Diseases: A Systematic Review and Meta- analysis. Journal of Sport Biosciences. 2023; 15 (1):71-87.

DOI: http//doi.org/10.22059/JSB.2023.354347.1570

Journal of Sport Biosciences by University of Tehran Press is licensed under CC BY-NC 4.0.

Web site: https://jsb.ut.ac.ir/ | Email: [email protected].

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Extended Abstract

Introduction

Obesity is the result of an imbalance between energy intake and consumption, which leads to the accumulation of adipose tissue. Accumulation of adipose tissue, especially visceral fat, is associated with the development of metabolic diseases such as type 2 diabetes. Adipose tissue also acts as an active endocrine organ that leads to the production and secretion of adipokines. Adipokines secreted from adipose tissue play important physiological roles such as regulation of metabolism and body homeostasis, and regulation of inflammation as well as insulin resistance, which are known as therapeutic targets for many metabolic disorders such as obesity and diabetes.

Leptin is known as one of the most important and well- known adipokines with pro-inflammatory effects.

physical training is one of the effective therapeutic interventions for obesity and its related diseases, which leads to weight loss, improvement of whole body metabolism, and improvement of insulin resistance and inflammation. However, the effects of exercise depend on the type of exercise. In recent years, High-Intensity Interval Training (HIIT) has been recognized as one of the most effective exercise methods to prevent obesity.

Therefore, this study aimed to investigate the effect of HIIT on serum leptin levels in individuals with and without chronic diseases.

Methods

A comprehensive search was conducted in Persian and English articles published until December 2022, in PubMed, Scopus, Web of Science, SID, and Magiran databases using relevant keywords. After selecting desired articles based on the inclusion criteria, a meta- analysis of the results was performed using CMA2 software. Effect size (SMD) and 95% confidence interval were calculated using random effect models.

Heterogeneity was assessed using I², and for the

publication bias, the Funnel Plot test and the Egger test were used.

Results

The results of data analysis showed that HIIT led to a significant decrease in leptin [-0.28 (CI: -0.07 to -0.48), p=0.008]. Also, the data analysis of 9 interventions showed that there was no significant difference between HIIT and Medium Intensity Continuous Training (MICT) on circulating leptin levels [-0.03, (CI:-0.34 to 0.27), p=0.82]. The results of the subgroup analysis based on health status showed that HIIT leads to a significant reduction of leptin in people with chronic diseases.

Conclusion

In general, the findings of this study showed that HIIT is an effective training method to reduce leptin in people with chronic diseases, while healthy people may not be affected by this type of training. The beneficial effects of HIIT were shown in individuals with chronic diseases, which indicates that the reduction of leptin following HIIT may be one of the effective factors in improving the health indicators of these people. In addition, despite the lack of significant differences between HIIT and MICT protocols, HIIT appears to be a time-efficient exercise method for leptin reduction.

Ethical Considerations Compliance with ethical guidelines: Not applicable.

Funding: This research did not receive any specific grant or other

extramural funding.

Authors’ contribution: Mohammad Javad Pourvaghar, Saeed Reza

Noori Mofrad, and Mousa Khalafi carried out the screenings and reviews, analyzing data, performing a meta-analysis, and drafting the manuscript. All authors read and approved the final version of the manuscript.

Conflict of interest: The authors declare that there are no conflicts of interest.

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ﺛﺄﺗ ﯿ ﺮ ﺮﻤﺗ ﯾ ﻦ ﺑوﺎﻨﺗ ﯽ ﻻﺎﺑ تﺪﺷ ﺎﺑ ﺘﭙﻟ حﻮﻄﺳ ﺮﺑ

ﯿ ﻦ ﺷدﺮﮔ ﯽ نوﺪﺑ و ﺎﺑ داﺮﻓا رد ﺑﯿ

رﺎﻤ ي ﺎﻫ ي روﺮﻣ :ﻦﻣﺰﻣ ي

مﺎﻈﻧ ﺪﻨﻣ ﻠﺤﺗاﺮﻓ و ﯿ

ﻞ

رﺎﻗورﻮﭘ داﻮﺟﺪﻤﺤﻣ

1

، 

دﺮﻔﻣ يرﻮﻧ ﺎﺿرﺪﯿﻌﺳ ﯽﻔﻠﺧ ﯽﺳﻮﻣ ،2

3

1 . ﻮﻧ ﯾ ﺪﻨﺴ ة ،لوﺆﺴﻣ هوﺮﮔ ﯽﺷزرو مﻮﻠﻋ و ﯽﻧﺪﺑ ﺖﯿﺑﺮﺗ ،

ﮑﺸﻧاد ﺪ ة ﯽﻧﺎﺴﻧا مﻮﻠﻋ هﺎﮕﺸﻧاد ، نﺎﺷﺎﮐ ، نﺎﺷﺎﮐ :ﻪﻣﺎﻧﺎﯾار .ناﺮﯾا ، [email protected]

2 هوﺮﮔ . ﯽﺷزرو مﻮﻠﻋ و ﯽﻧﺪﺑ ﺖﯿﺑﺮﺗ ،

ﺪﮑﺸﻧاد ة ﯽﻧﺎﺴﻧا مﻮﻠﻋ هﺎﮕﺸﻧاد ، نﺎﺷﺎﮐ ، نﺎﺷﺎﮐ

، ناﺮﯾا :ﻪﻣﺎﻧﺎﯾار . [email protected]

3 . ﺑﺮﺗ هوﺮﮔ ﯿ ﺖ ﻧﺪﺑ ﯽ ﺷزرو مﻮﻠﻋ و ﯽ

، ﺪﮑﺸﻧاد ة ﻧﺎﺴﻧا مﻮﻠﻋ ﯽ

، ،نﺎﺷﺎﮐ ،نﺎﺷﺎﮐ هﺎﮕﺸﻧاد :ﻪﻣﺎﻧﺎﯾار .ناﺮﯾا

[email protected]

ﻪﻟﺎﻘﻣ تﺎﻋﻼﻃا هﺪﯿﮑﭼ

:ﻪﻟﺎﻘﻣ عﻮﻧ ﻠﺤﺗاﺮﻓ

ﯿ ﻞ

رﺎﺗ ﯾ ﺦ رد ﯾ ﺖﻓﺎ : 05 / 11 / 1401

:يﺮﮕﻧزﺎﺑ ﺦﯾرﺎﺗ 04

/ 02 / 1402

رﺎﺗ ﯾ ﺦ ﺬﭘ ﯾ شﺮ : 05 / 02 / 1402

رﺎﺗ ﯾ ﺦ رﺎﺸﺘﻧا : 05 / 02 / 1402

ﺪﯿﻠﮐ هژاو :ﺎﻫ

ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ

،

ﯽﻣواﺪﺗ ﻦﯾﺮﻤﺗ

،

ﯽﻗﺎﭼ

، ﻦﯿﺘﭙﻟ . ﻪﻣﺪﻘﻣ

: ﻘﺤﺗ فﺪﻫ ﯿ ﻖ ﺳرﺮﺑ ﺮﺿﺎﺣ ﯽ ﺮﺛا ﻻﺎﺑ تﺪﺷ ﺎﺑ ﻦﯾﺮﻤﺗ )

(HIIT ﻣﺮﺳ ﺢﻄﺳ ﺮﺑ ﯽ

ﺘﭙﻟ ﯿ ﻦ داﺮﻓا ﺑ نوﺪﺑ و ﺎ ﺑﯿ رﺎﻤ ي ﺎﻫ ي

.دﻮﺑ ﻦﻣﺰﻣ ر شو ﺶﻫوﮋﭘ : ا رد ﯾ ﻦ ﻘﺤﺗ ﯿ ﻖ زا ﺖﺴﺟ ﻮﺟو ي مﺎﻈﻧ ﺪﻨﻣ رد تﻻﺎﻘﻣ ﯽﺳرﺎﻓ ﻠﮕﻧا و ﯿ ﺴ ﯽ ﺸﺘﻨﻣ هﺪﺷﺮ ﺎﺗ ﺮﺒﻣﺎﺳد 2022

، رد

ﺎﭘﯾ هﺎﮕ ﺎﻫ ي ﺗﺎﻋﻼﻃا ﯽ ﺪﻤﺑﺎﭘ ،سﻮﭘﺎﮑﺳا ،ﺲﻨﯾﺎﺳ فآ بو

، ﻫﺎﮕﺸﻧاد دﺎﻬﺟ ﺰﮐﺮﻣ ﯽ

ﮕﻣ و ﯿ ناﺮ ﺎﺑ دﺎﻔﺘﺳا زا ه ﻠﮐ ﯿ هژاوﺪ ﺎﻫ ي

ﻻﺎﻘﻣ بﺎﺨﺘﻧا زا ﺲﭘ .ﺖﺳا هﺪﺷ هدﺎﻔﺘﺳا طﻮﺑﺮﻣ ت

ﺮﻈﻧدرﻮﻣ سﺎﺳا ﺮﺑ و ﻌﻣ

ﯿ ﺎﻫرﺎ ي ﻪﺑ دورو ﻘﺤﺗ ﻖﯿ

، اﺮﻓ ﻠﺤﺗ ﯿ ﻞ ﺘﻧ ﺎﯾ ﺞ مﺎﺠﻧا

ﺖﻓﺮﮔ . زاﺪﻧا ة ) ﺮﺛا و (SMD ﻠﺻﺎﻓ ﮥ ﻤﻃا ﯿ نﺎﻨ 95 زا هدﺎﻔﺘﺳا ﺎﺑ ،ﺪﺻرد مﺮﻧ

راﺰﻓا 2 اﺮﺑ .ﺪﺷ ﻪﺒﺳﺎﺤﻣ CMA

ي ﺳرﺮﺑ ﯽ

ﻧﻮﮕﻤﻫﺎﻧ ﯽ

، نﻮﻣزآ زا I2

اﺮﺑ و ي ﮔﻮﺳ ﯿﺮ ي زا رﺎﺸﺘﻧا ﻮﻓ نﻮﻣزآ ﻧ تﻼﭘ ﻞ ﺖﺴﺗ و Egger هدﺎﻔﺘﺳا .ﺪﺷ ﯽﻣﺎﻤﺗ ﻠﺤﺗ ﯿ ﻞ ﺎﻫ ﺎﺑ

هدﺎﻔﺘﺳا مﺮﻧ راﺰﻓا مﺎﺠﻧاCMA2

ﺖﻓﺮﮔ .

ﯾ ﻪﺘﻓﺎ ﺎﻫ ﺎﺘﻧ: ﯾ ﺞ ﻠﺤﺗ ﯿ ﻞ هداد ﺎﻫ نﺎﺸﻧ داد ﻪﮐ ﺶﻫﺎﮐ ﻪﺑHIIT

ﺎﻨﻌﻣ راد ﺘﭙﻟ ﯿ ]ﻦ 008 /0 )،P=

07 /0 - ﺎﺗ 48 /0 CI: - (

28 /0 [ - ﺮﺠﻨﻣ ﺪﺷ . ﻨﭽﻤﻫ ﯿ ﻦ ﻟﺎﻧآ ﯿﺰ هداد ﺎﻫ ي 9 توﺎﻔﺗ ﻪﮐ داد نﺎﺸﻧ ﻪﻠﺧاﺪﻣ ﺎﻨﻌﻣ

راد ي ﺑﯿ ﻦ وHIIT ﯽﻣواﺪﺗ ﻦﯾﺮﻤﺗ

) (MICT ﺑ دﺎﻘﻣ ﺮ ﯾﺮ ﺷدﺮﮔ ﯽ ﺘﭙﻟ ﯿ ﻦ دﻮﺟو ﺖﺷاﺪﻧ ] 82 P= /0 )،

27 /0 ﺎﺗ 34 CI: - /0 ( 03 - /0 [ . ﺎﺘﻧ ﯾ ﺞ ﻠﺤﺗ ﯿ ﻞ

زﯾ ﻫوﺮﮔﺮ ﯽ سﺎﺳا ﺮﺑ ﻌﺿو ﯿ ﺖ ﺘﻣﻼﺳ ﯽ ﻧدﻮﻣزآ ﯽ ﺎﻫ ﻪﮐ داد نﺎﺸﻧ ﺶﻫﺎﮐ ﻪﺑHIIT

ﺎﻨﻌﻣ راد ﺘﭙﻟ ﯿ ﻦ ﺎﺑ داﺮﻓا رد ﺑﯿ رﺎﻤ ي ﺎﻫ ي

ﻦﻣﺰﻣ ﺮﺠﻨﻣ ﻣ ﯽ دﻮﺷ .

ﺚﺤﺑ : دﺎﻘﻣ ﺶﻫﺎﮐ ﻪﺑHIIT ﯾﺮ

ﻧﻮﺧ شدﺮﮔ ﯽ ﺘﭙﻟ ﯿ

،ﻦ ﻪﺑ وﯾ هﮋ رد ﺎﺑ داﺮﻓا ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻦﻣﺰﻣ ﺮﺠﻨﻣ ﻣ ﯽ دﻮﺷ ﺪﻋ دﻮﺟو ﺎﺑ . م

توﺎﻔﺗ ﺎﻨﻌﻣ راد ﺑﯿ ﻦ وHIIT ،MICT ﮥﻠﺧاﺪﻣHIIT

نوﺮﻘﻣ ﻧﺎﻣز ظﺎﺤﻟ زا ﻪﻓﺮﺻ ﻪﺑ ﯽ

اﺮﺑ ي ﺶﻫﺎﮐ ﻟﺘﭙ ﯿ ﻦ ﺖﺳا .

دﺎﻨﺘﺳا : ،رﺎﻗورﻮﭘ داﻮﺟﺪﻤﺤﻣ

؛ دﺮﻔﻣ يرﻮﻧ ،ﺎﺿرﺪﯿﻌﺳ ﺧ و؛

ﯽﻔﻠ ﯽﺳﻮﻣ ، . ﺛﺄﺗ ﯿﺮ ﺮﻤﺗ ﯾ ﻦ ﺑوﺎﻨﺗ ﯽ ﺘﭙﻟ حﻮﻄﺳ ﺮﺑ ﻻﺎﺑ تﺪﺷ ﺎﺑ ﯿ

ﻦ ﺷدﺮﮔ ﯽ نوﺪﺑ و ﺎﺑ داﺮﻓا رد ﺑﯿ

رﺎﻤ ي ﺎﻫ ي :ﻦﻣﺰﻣ

روﺮﻣ ي مﺎﻈﻧ ﺪﻨﻣ ﻠﺤﺗاﺮﻓ و ﯿ ﻞ ﺮﺸﻧ . ﯾﮥ ز مﻮﻠﻋ ﯾ ﺘﺴ ﯽ ﺷزرو ﯽ . 1402

؛ 15 )1 (:

87 - 71 . DOI:

http//doi.org/10.22059/JSB.2023.354347.1570 ﻪﺑ ﯽﺳﺮﺘﺳد اﯾ

ﻦ ﺮﺸﻧ ﯾﻪ ﻤﻠﻋ

،ﯽ ار ﯾ نﺎﮕ ﮑﻟﺎﻣ ﻖﺣ و ﺖﺳا ﯿ

ﺖ ﺮﮑﻓ ي ﻻ سﺎﺳا ﺮﺑ ار دﻮﺧ ﯾ

ﺲﻨﺴ ﺮﮐ ﯾﺘ ﯿﻮ ) ﺰﻨﻣﺎﮐ CC BY-NC 4.0 ﻪﺑ (

ﻮﻧ ﯾ نﺎﮔﺪﻨﺴ ﺖﺳا هدﺮﮐ راﺬﮔاو .

:ﻪﯾﺮﺸﻧ سردآ| /

https://jsb.ut.ac.ir :ﻞﯿﻤﯾا|

ut.ac.ir jsb@

ﺎﻧ :ﺮﺷ تارﺎﺸﺘﻧا .ناﺮﻬﺗ هﺎﮕﺸﻧاد .نﺎﮔﺪﻨﺴﯾﻮﻧ©

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74

رﺎﻬﺑ ،لوا ةرﺎﻤﺷ ،ﻢﻫدﺰﻧﺎﭘ ةرود ،ﯽﺷزرو ﯽﺘﺴﯾز مﻮﻠﻋ 1402

ﻪﻣﺪﻘﻣ ﯽﻗﺎﭼ ﮥﺠﯿﺘﻧ ﯽﻓﺮﺼﻣ و ﯽﺘﻓﺎﯾرد يژﺮﻧا ﻦﯿﺑ لدﺎﻌﺗ مﺪﻋ ﺖﺳا

ﺮﺠﻨﻣ ﻪﮐ ﺖﻓﺎﺑ ﺖﺷﺎﺒﻧا ﻪﺑ

ﯽﺑﺮﭼ ﻣ ﯽ دﻮﺷ ﯽﺑﺮﭼ ﺖﻓﺎﺑ ﺖﺷﺎﺒﻧا . ﻪﺑ

وﯾ هﮋ ﯽﺑﺮﭼ

ﺎﺑ ﯽﯾﺎﺸﺣا ﮥﻌﺳﻮﺗ

ﺑﯿ ﺎﻤ ر ي ﺎﻫ ي عﻮﻧ ﺖﺑﺎﯾد ﺪﻨﻧﺎﻣ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ 2

ﯽﺑﺮﭼ ﺖﻓﺎﺑ .ﺖﺳا هاﺮﻤﻫ هوﻼﻋ

ﺮﺑ ةﺮﯿﺧذ ،يژﺮﻧا ﻪﺑ ناﻮﻨﻋ

ُا ﮏﯾ نﺎﮔر نورد رﯾ ﺰ

ﻞﻤﻋ لﺎﻌﻓ ﻣ

ﯽ ﺪﻨﮐ ﺢﺷﺮﺗ و ﺪﯿﻟﻮﺗ ﻪﺑ ﻪﮐ ﻦﯿﮐﻮﺘﯾﺎﺳﻮﭙﯾدآ

ﺎﻫ ﺮﺠﻨﻣ ﻣ ﯽ دﻮﺷ ) 1 . ( ﻦﯾﺎﮐﻮﭙﯾدآ ﯽﺑﺮﭼ ﺖﻓﺎﺑ زا ﻪﺤﺷﺮﺘﻣ يﺎﻫ

تاﺮﯿﺛﺄﺗ ﯽﮑﯾژﻮﻟﻮﯾﺰﯿﻓ

ﻢﯿﻈﻨﺗ ﺪﻨﻧﺎﻣ ﻢﻬﻣ ﺖﺧﻮﺳ

زﺎﺳو ﺎﻔﯾا ﻦﯿﻟﻮﺴﻧا ﻪﺑ ﺖﻣوﺎﻘﻣ ﻦﯿﻨﭽﻤﻫ و بﺎﻬﺘﻟا ﻢﯿﻈﻨﺗ ،نﺪﺑ زﺎﺘﺳﻮﻤﻫ و ﻣ

ﯽ ﺪﻨﻨﮐ فﺪﻫ ﻪﮐ ، زا يرﺎﯿﺴﺑ ﯽﻧﺎﻣرد

ﺖﺑﺎﯾد و ﯽﻗﺎﭼ ﺪﻨﻧﺎﻣ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ تﻻﻼﺘﺧا ﯽﻣ بﻮﺴﺤﻣ

دﻮﺷ ) 1 ( .

ﻦﯾﺎﮐﻮﭙﯾدآ ﯽﺑﺮﭼ ﺖﻓﺎﺑ زا ﻖﺘﺸﻣ يﺎﻫ

ﻪﺑ رﻮﻃ ﯽﻠﮐ تاﺮﯿﺛﺄﺗ ﺶﯿﭘ ﺎﯾ ﯽﺑﺎﻬﺘﻟا ﺑﺎﻬﺘﻟاﺪﺿ

ﯽ راد ﺪﻧ ﻦﯿﺘﭙﻟ ﻪﮐ ﻪﺑ

ناﻮﻨﻋ زا ﯽﮑﯾ ﻢﻬﻣ ﺮﺗ ﯾ ﻦ و

ﻪﺘﺧﺎﻨﺷ هﺪﺷ ﺮﺗ ﯾ ﻦ ﻦﯾﺎﮐﻮﭙﯾدآ ياراد ﺎﻫ ﺶﯿﭘ تاﺮﯿﺛﺄﺗ

ﯽﺑﺎﻬﺘﻟا ﻪﺘﺧﺎﻨﺷ ﺖﺳا هﺪﺷ )

2 ( ﻦﯿﺘﭙﻟ . ﻪﺑ ناﻮﻨﻋ ﮏﯾ ﻦﯾﺎﮐﻮﭙﯾدآ رد

،شدﺮﮔ ﻪﺑ ةﺪﻧﺮﯿﮔ ﻦﯿﺘﭙﻟ

رد ﮥﺘﺴﻫ ﯽﻧﺎﻤﮐ ﻻﺎﺗﻮﭙﯿﻫ سﻮﻣ ﻞﺼﺘﻣ ﻣ ﯽ دﻮﺷ

، ﯽﯾﺎﺟ ﻪﮐ ﻪﺑ ناﻮﻨﻋ ﮏﯾ نﻮﻣرﻮﻫ بﻮﮐﺮﺳ ﺪﻨﻨﮐ ة ﺎﻬﺘﺷا ﻞﻤﻋ ﻣ ﯽ ﺪﻨﮐ ﻪﮐ فﺮﺼﻣ اﺬﻏ و يژﺮﻧا

ار ﻢﯿﻈﻨﺗ ﻣ ﯽ ﺪﻨﮐ ) 3 ( . هوﻼﻋ ﺮﺑ و ﺰﮐﻮﻠﮔ ﻢﺴﯿﻟﻮﺑﺎﺘﻣ ،نﺪﺑ نزو ﻢﯿﻈﻨﺗ ﻪﻠﻤﺟ زا يﺮﮕﯾد ﯽﮑﯾژﻮﻟﻮﯾﺰﯿﻓ و ﯽﮑﯿﻟﻮﺑﺎﺘﻣ يﺎﻫﺪﻨﯾاﺮﻓ رد ﻦﯿﺘﭙﻟ ،ﻦﯾا

دراد ﺶﻘﻧ ﻦﯿﻟﻮﺴﻧا ﻪﺑ ﺖﻣوﺎﻘﻣ و بﺎﻬﺘﻟا ،ﯽﺑﺮﭼ )

4 (.

تﺎﻘﯿﻘﺤﺗ مﺎﺠﻧا

ﺘﻓﺮﮔ ﻪ نﺎﺸﻧ هداد ﺪﻧا و تﻻﻼﺘﺧا ﻪﮐ ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﯽﻗﺎﭼ ﺪﻨﻧﺎﻣ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ

عﻮﻧ ﺖﺑﺎﯾد و 2

ﻦﯿﻨﭽﻤﻫ و ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﯽﺒﻠﻗ - دﺎﻘﻣ ﺶﯾاﺰﻓا ﺎﺑ ﯽﻗوﺮﻋ ﻦﯿﺘﭙﻟ ﯽﺷدﺮﮔ ﺮﯾ

هاﺮﻤﻫ ﺪﻧا ) 4 ، 5 (.

هوﻼﻋ ﺮﺑ ا ،ﻦﯾ تﺎﻘﯿﻘﺤﺗ مﺎﺠﻧا

ﺘﻓﺮﮔ ﻪ

نﺎﺸﻧ هداد ﺪﻧا ﻦﯿﺘﭙﻟ ﻪﺑ ﺖﻣوﺎﻘﻣ دﻮﺒﻬﺑ ﻪﮐ ﺖﺳا هاﺮﻤﻫ ﺰﯿﻧ ﻦﯿﺘﭙﻟ ﻪﺑ ﺖﻣوﺎﻘﻣ زا ﯽﺷﺎﻧ ﯽﻤﻨﯿﺘﭙﻟﺮﭙﯾﺎﻫ ﺎﺑ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ تﻻﻼﺘﺧا و ﯽﻗﺎﭼ ﻣ

ﯽ ﺪﻧاﻮﺗ

ياﺮﺑ ﯽﻧﺎﻣرد فﺪﻫ ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﺪﺷﺎﺑ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ )

5 (.

ﯽﻧﺎﻣرد تﻼﺧاﺪﻣ زا ﻢﻈﻨﻣ ﯽﺷزرو تﺎﻨﯾﺮﻤﺗ ﺮﺛﺆﻣ

و ﯽﻗﺎﭼ ياﺮﺑ ﺑﯿ

رﺎﻤ ي ﺎﻫ نآ ﺎﺑ ﻂﺒﺗﺮﻣ ﺖﺳا

دﻮﺒﻬﺑ ،نزو ﺶﻫﺎﮐ ﻪﺑ ﻪﮐ ﺖﺧﻮﺳ

زﺎﺳو ﻞﮐ

بﺎﻬﺘﻟا ﻦﯿﻨﭽﻤﻫ و ﻦﯿﻟﻮﺴﻧا ﻪﺑ ﺖﻣوﺎﻘﻣ دﻮﺒﻬﺑ ،نﺪﺑ ﺮﺠﻨﻣ

ﻣ ﯽ دﻮﺷ ،لﺎﺣ ﻦﯾا ﺎﺑ . تاﺮﯿﺛﺄﺗ

ﯽﺷزرو ﻦﯾﺮﻤﺗ عﻮﻧ ﻪﺑ ﯽﺷزرو تﺎﻨﯾﺮﻤﺗ ﻪﺘﺴﺑاو

ﺖﺳا

رد ﻪﮐ لﺎﺳ ﺎﻫ ي ﻻﺎﺑ تﺪﺷ ﺎﺑ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ ﺮﯿﺧا ﻪﺑ1

ناﻮﻨﻋ زا ﯽﮑﯾ ﺮﺗﺮﺛﺆﻣ ﯾ ﻦ شور ﺎﻫ ي نآ ﺎﺑ ﻂﺒﺗﺮﻣ نارﺎﻤﯿﺑ و قﺎﭼ داﺮﻓا ياﺮﺑ ﯽﻨﯾﺮﻤﺗ

ﺖﺳا هﺪﺷ ﻪﺘﺧﺎﻨﺷ )

9 - 6 ( . ﺎﺷ HIIT

ﻞﻣ ﻪﻠﻫو ﺎﻫ ي ﺎﺑ ﺪﯾﺪﺷ ﺖﯿﻟﺎﻌﻓ هرود

ﺎﻫ ي و ﺖﺳا ﺖﺣاﺮﺘﺳا زا ﯽﺻﺎﺧ

ًﻻﻮﻤﻌﻣ رد تﺪﺷ ﺎﻫ ﯽﯾ ﻦﯿﺑ 80 ﺎﺗ

100 مﺎﺠﻧا ﯽﻓﺮﺼﻣ نﮋﯿﺴﮐا ﺮﺜﮐاﺪﺣ ﺎﯾ ﻪﻨﯿﺸﯿﺑ ﺐﻠﻗ نﺎﺑﺮﺿ ﺪﺻرد ﻣ

ﯽ ﺮﯿﮔ د ) 6

، 7 ( .

تﺎﻘﯿﻘﺤﺗ ﻞﯿﻠﺤﺗاﺮﻓ

مﺎﺠﻧا ﮥﺘﻓﺮﮔ ﯽﻠﺒﻗ تاﺮﯿﺛﺄﺗ ﺶﻫﺎﮐ ،ﻦﯿﻟﻮﺴﻧا ﻪﺑ ﺖﻣوﺎﻘﻣ دﻮﺒﻬﺑ رد تﺎﻨﯾﺮﻤﺗ عﻮﻧ ﻦﯾا زا يﺪﯿﻔﻣ ةدﻮﺗ

ﯽﺑﺮﭼ ﻪﺑ وﯾ هﮋ

شراﺰﮔ ﯽﺴﻔﻨﺗ ﯽﺒﻠﻗ ﯽﮔدﺎﻣآ دﻮﺒﻬﺑ و يﺪﺒﮐ و ﯽﯾﺎﺸﺣا ﯽﺑﺮﭼ هدﺮﮐ

ﺪﻧا تاﺮﺛا ﯽﺘﺣ ﺞﯾﺎﺘﻧ زا ﯽﺧﺮﺑ ﻪﮐ گرﺰﺑ

ﺮﺗ ي ﺖﺒﺴﻧ تﺎﻨﯾﺮﻤﺗ عﻮﻧ ﻦﯾا زا

ﺎﺑ ﯽﻣواﺪﺗ ﻦﯾﺮﻤﺗ ﻪﺑ ﻂﺳﻮﺘﻣ تﺪﺷ

ﻪﺋارا2

هدﺮﮐ ﺪﻧا ) 8

، 9 ( رد . ﮥﻨﯿﻣز ﯽﻨﯿﻟﺎﺑ تﺎﻌﻟﺎﻄﻣ ،ﻦﯿﺘﭙﻟ مﺎﺠﻧا

هﺪﺷ نﺎﺸﻧ هداد ﺪﻧا ﺎﻨﯾﺮﻤﺗ عﻮﻧ ﻦﯾا ﻪﮐ ت

ﻦﯿﺘﭙﻟ ﺶﻫﺎﮐ ﻪﺑ ﺖﺳا ﻦﮑﻤﻣ ﺮﺠﻨﻣ

دﻮﺷ ؛ دﻮﺟو ﺎﺑ ﻦﯾا ﺶﻫوﮋﭘ يﺎﻫ تاﺮﯿﯿﻐﺗ مﺪﻋ ﺮﮕﯾد ﺮﯿﮕﻤﺸﭼ

شراﺰﮔ ار هدﺮﮐ

ﺪﻧا ) 10 ، 11 ( .

) نارﺎﮑﻤﻫ و ﯽﻔﻠﺧ ﻞﯿﻠﺤﺗاﺮﻓ 2020

ﻣ تﻻﻼﺘﺧا ﺎﺑ داﺮﻓا رد ﺰﯿﻧ ( ﺖﺳا ﻦﮑﻤﻣ ﻪﮐ ﺖﺳا هدﺮﮐ دﺎﻬﻨﺸﯿﭘ ﺰﯿﻧ ﯽﮑﯿﻟﻮﺑﺎﺘ

ﺶﻫﺎﮐ ﻪﺑ ﺮﺠﻨﻣHIIT

زا ﯽﻤﮐ داﺪﻌﺗ ﯽﻠﺒﻗ ﻞﯿﻠﺤﺗاﺮﻓ ،لﺎﺣ ﻦﯾا ﺎﺑ .دﻮﺷ ﻦﯿﺘﭙﻟ تﺎﻘﯿﻘﺤﺗ

مﺎﺠﻧا ﻪﺘﻓﺮﮔ تﺎﻌﻟﺎﻄﻣ ﻪﺑ ﺎﻬﻨﺗ ﻪﮐ دﻮﺑ پﺎﭼ

هﺪﺷ تﻼﺠﻣ رد ﻠﮕﻧا

ﯿ ﺴ ﯽ نﺎﺑز

دوﺪﺤﻣ دﻮﺑ ) 12 ( . ﺟو ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ تﻻﺎﻘﻣ ندﺮﮐ ﻪﻓﺎﺿا و ﺪﯾﺪﺟ ﯽﻨﯿﻟﺎﺑ تﺎﻌﻟﺎﻄﻣ دﻮ

پﺎﭼ هﺪﺷ ﯽﺳرﺮﺑ نﺎﮑﻣا ﯽﺳرﺎﻓ تﻼﺠﻣ رد ﻗد

ﯿ ﻖ ﺮﺗ ﺛﺄﺗ ﯿﺮ

ﺴﯾﺎﻘﻣ ﻦﯿﻨﭽﻤﻫ و ﻦﯿﺘﭙﻟ ﺮﺑ HIIT

ﮥ ﻞﮑﺗوﺮﭘ عﻮﻧ ود ﻦﯿﺑ ﺎﺑ HIIT

.ﺖﺳا هﺪﺷ ﻢﻫاﺮﻓ MICT

ازا ﯾ ﻦ ور فﺪﻫ ﻖﯿﻘﺤﺗ ﯽﺳرﺮﺑ ﺮﺿﺎﺣ ﺛﺄﺗ

ﯿﺮ

نوﺪﺑ و ﺎﺑ داﺮﻓا رد ﻦﯿﺘﭙﻟ ﯽﺷدﺮﮔ ﺮﯾدﺎﻘﻣ ﺮﺑHIIT

ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻦﻣﺰﻣ ﺖﺳا .

1 . High intensity interval training (HIIT)

2 . Moderate-intensity continous training (MICT)

(5)

ﯿﺘﭙﻟ حﻮﻄﺳ ﺮﺑ ﻻﺎﺑ تﺪﺷ ﺎﺑ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ ﺮﯿﺛﺄﺗ يرﺎﻤﯿﺑ نوﺪﺑ و ﺎﺑ داﺮﻓا ﺮﺑ ﯽﺷدﺮﮔ ﻦ

... ﻦﻣﺰﻣ يﺎﻫ 75

شور ﺳﺎﻨﺷ ﯽ ﺶﻫوﮋﭘ

ﺶﻫوﮋﭘ ﺮﺿﺎﺣ زا عﻮﻧ تﺎﻌﻟﺎﻄﻣ يروﺮﻣ مﺎﻈﻧ ﺪﻨﻣ هاﺮﻤﻫ ﺎﺑ ﻞﯿﻠﺤﺗاﺮﻓ ﺖﺳا

ﻪﮐ ﺮﺑ سﺎﺳا ﻦﯾﺮﮐﺎﮐ ﻞﻤﻌﻟارﻮﺘﺳد

1 و دراﻮﻣ ﯽﺤﯿﺟﺮﺗ رد شراﺰﮔ

يﺎﻫروﺮﻣ مﺎﻈﻧ

ﺪﻨﻣ و ﻞﯿﻠﺤﺗاﺮﻓ مﺎﺠﻧا2

ﺘﻓﺮﮔ ﻪ ﺖﺳا .

شور ﺖﺴﺟ ﻮﺟو ي هداد ﺎﻫ

ﺖﺴﺟ ﻮﺟو ي ﻊﻣﺎﺟ رد ﺎﭘﯾ هﺎﮕ ﺎﻫ ي ﯽﺗﺎﻋﻼﻃا

،ﺪﻤﺑﺎﭘ ،سﻮﭘﺎﮑﺳا ،ﺲﻨﯾﺎﺳ فآ بو ﯽﻫﺎﮕﺸﻧاد دﺎﻬﺟ ﺰﮐﺮﻣ

دﺎﻔﺘﺳا ﺎﺑ ناﺮﯿﮕﻣ و زا ه

ﻠﮐ ﯿ اوﺪ هژ ﺎﻫ ي

ﺎﺗ ﯽﺼﺼﺨﺗ ﺮﺒﻣﺎﺳد

2022 مﺎﺠﻧا .ﺖﻓﺮﮔ ﻠﮐ ﯿ هژاوﺪ ﺎﻫ ي ﻪﺑ رﺎﮐ ﻪﺘﻓﺮﮔ هﺪﺷ ﻞﻣﺎﺷ دراﻮﻣ ﺮﯾز :دﻮﺑ

"high intensity interval training" or "high intensity interval exercise" or "high intensity intermittent training"

or "high intensity intermittent exercise" or "aerobic interval training" or "aerobic interval exercise" or

"interval training" or "interval exercise" or "sprint interval training" or "sprint interval exercise" or "HIIT" or

"SIT" and "Leptin"

هوﻼﻋ ﺮﺑ ﺖﺳﺮﻬﻓ ،ﻦﯾا تﻻﺎﻘﻣ

جاﺮﺨﺘﺳا هﺪﺷ ﻪﺑ شور ﯽﺘﺳد ﺖﺴﺟ ﻮﺟو ﺪﺷ . ﺖﺴﺟ ﻮﺟو ي ﯾﺎﺳ رد ﯽﺘﺳد ﺖ

Google Scholar

ﺪﺷ مﺎﺠﻧا ﺰﯿﻧ .

تﻻﺎﻘﻣ ﻦﺘﻓﺎﯾ ياﺮﺑ ژاوﺪﯿﻠﮐ ﯽﺳرﺎﻓ

ه يﺎﻫ » ﻦﯾﺮﻤﺗ ﯽﺑوﺎﻨﺗ

«،

» ﺪﯾﺪﺷ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ

«،

» ﺎﺑ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ ﺷ

ﻻﺎﺑ تﺪ

«،

» ﻋﺮﺳ ﻦﯾﺮﻤﺗ ﯽﺘ

« و

» ﻦﯿﺘﭙﻟ

« .ﺪﺷ هدﺎﻔﺘﺳا ﺖﺴﺟ

و ﻮﺟ رد ﺎﭘ ﯾ هﺎﮕ ﺎﻫ ي ﯽﺗﺎﻋﻼﻃا ﻪﺑ

ترﻮﺻ ﻞﻘﺘﺴﻣ ود ﻂﺳﻮﺗ هﺪﻨﺴﯾﻮﻧ

م) ج

،پ ر س مﺎﺠﻧا (م ن ﺪﺷ

و ﻫ ﻪﻧﻮﮔﺮ

فﻼﺘﺧا ﺮﻈﻧ ﺎﺑ ترﻮﺸﻣ ﻖﯾﺮﻃ زا ﺪﻨﺴﯾﻮﻧ

ة .ﺪﺷ ﻞﺣ (خ م) مﻮﺳ

يﺎﻫرﺎﯿﻌﻣ دورو

و جوﺮﺧ

ﯽﺗﺎﻌﻟﺎﻄﻣ ﺎﺑ

وﯾ ﮔﮋ ﯽ ﺎﻫ ي ﺮﯾز دراو ﻞﯿﻠﺤﺗاﺮﻓ ﺮﺿﺎﺣ

ﺪﻧﺪﺷ : 1.

تﺎﻌﻟﺎﻄﻣ پﺎﭼ

هﺪﺷ رد تﻼﺠﻣ ﯽﺴﯿﻠﮕﻧا و

ﺳرﺎﻓ ﯽ نﺎﺑز

، 2 . تﺎﻌﻟﺎﻄﻣ ﺎﺑ

ﻧدﻮﻣزآ ﯽ ﺎﻫ ي نﺎﺴﻧا فﺮﺻ ﺮﻈﻧ ﺲﻨﺟ و ﻦﺳ ،ﯽﺘﻣﻼﺳ ﺖﯿﻌﺿو زا

، 3 . تﺎﻌﻟﺎﻄﻣ ﺳرﺮﺑ ﯽ ﺪﻨﻨﮐ ة ﺮﺛا

(HIIT)

ﺎﺑ ﻃ لﻮ ﮥﻠﺧاﺪﻣ ﺮﺘﺸﯿﺑ ﻪﺘﻔﻫ ود زا و

4.

ﺎﺑ تﺎﻌﻟﺎﻄﻣ هزاﺪﻧا

ﮔﯿ ﺮ ي رد .ﻦﯿﺘﭙﻟ ﯽﯾﺎﻤﺳﻼﭘ ﺎﯾ ﯽﻣﺮﺳ ﺮﯾدﺎﻘﻣ صﻮﺼﺧ

،تﺎﻌﻟﺎﻄﻣ عﻮﻧ تﻼﺧاﺪﻣ

زآرﺎﮐ ﯽﯾﺎﻣ ﯽﻨﯿﻟﺎﺑ ﺎﺑ و ﺪﺑ نو هوﺮﮔ لﺮﺘﻨﮐ

دراو .ﺪﻧﺪﺷ ﻖﯿﻘﺤﺗ رد

صﻮﺼﺧ عﻮﻧ ﻪﻠﺧاﺪﻣ

(HIIT)

ﻞﮑﺗوﺮﭘ ، ﯽﺷزرو

ﺖﺳا ﻪﮐ ﻪﺑ ﻪﻠﻫو ﺎﻫ ي ﺖﯿﻟﺎﻌﻓ ﯽﺷزرو ﺎﺑ ﺷ تﺪ ﻻﺎﺑ هرﺎﺷا دراد ﻪﮐ رد

ةدوﺪﺤﻣ 80 ﺎﺗ 100 ﺪﺻرد نﺎﺑﺮﺿ ﺐﻠﻗ ﻪﻨﯿﺸﯿﺑ

، ﺎﺑ هرود ﺎﻫ ي ﺖﺣاﺮﺘﺳا لﺎﻌﻓ

ﺎﯾ لﺎﻌﻓﺮﯿﻏ مﺎﺠﻧا ﺖﻓﺮﮔ ﯾﺮﻤﺗ . تﺎﻨ ﯽﺑوﺎﻨﺗ ﯽﺘﻋﺮﺳ

(SIT)

رد ﻢﻫ

ﻦﯾا ﻞﻣﺎﺷ ﻪﮐ ﺖﺷاد ﺶﻘﻧ ﺶﻫوﮋﭘ ﻪﻠﻫو

ﺎﻫ ي ﺖﯿﻟﺎﻌﻓ ﯽﺷزرو ﺎﺑ تﺪﺷ ﺮﺜﮐاﺪﺣ ﺎﯾ قﻮﻓ ﺮﺜﮐاﺪﺣ ﺎﺑ ناﻮﺗ هرود ﺎﻫ ي ﯽﺘﺣاﺮﺘﺳا لﺎﻌﻓ

و ﻏﯿ لﺎﻌﻓﺮ

ﺖﺳا ﻪﮐ ، ﻪﺑ ناﻮﻨﻋ ﯽﻋﻮﻧ زا تﺎﻨﯾﺮﻤﺗ دHIIT

ﻪﺘﺳ ﺪﻨﺑ ي رد .ﺪﺷ صﻮﺼﺧ ﻧدﻮﻣزآ

ﯽ ﺎﻫ ﺮﺑ ﯽﺘﯾدوﺪﺤﻣ ، داﺮﻓا ﯽﺘﻣﻼﺳ ﺖﯿﻌﺿو و ﺲﻨﺟ ،ﻦﺳ يا

.ﺪﺸﻧ لﺎﻤﻋا جاﺮﺨﺘﺳا هداد

ﺎﻫ

جاﺮﺨﺘﺳا هداد ﺎﻫ ﻪﺑ ترﻮﺻ عﻮﻧ ﺮﻫ و ﺪﺷ مﺎﺠﻧا هﺪﻨﺴﯾﻮﻧ ود ﻂﺳﻮﺗ ﻞﻘﺘﺴﻣ فﻼﺘﺧا

ﺮﻈﻧ ﺎﺑ ترﻮﺸﻣ ﻖﯾﺮﻃ زا ﺪﻨﺴﯾﻮﻧ

ة .ﺪﺷ ﻞﺣ مﻮﺳ تﺎﻋﻼﻃا

ﻊﻤﺟ روآ ي هﺪﺷ دﻮﺑ ﺮﯾز دراﻮﻣ ﻞﻣﺎﺷ :

1.

و ﯾ ﮔﮋ ﯽ ﺎﻫ ي تﺎﻌﻟﺎﻄﻣ ﻞﻣﺎﺷ عﻮﻧ ﻪﻌﻟﺎﻄﻣ و ﻢﺠﺣ ﻪﻧﻮﻤﻧ

، 2.

وﯾ ﮔﮋ ﯽ ﺎﻫ ي ﻧدﻮﻣزآ ﯽ ﺎﻫ ﻞﻣﺎﺷ ﻦﺳ و

ﺺﺧﺎﺷ دﻮﺗ ة ﯽﻧﺪﺑ (BMI)

، 3.

و ﯾ ﮔﮋ ﯽ ﺎﻫ ي تﻼﺧاﺪﻣ ﯽﺷزرو

ﻞﻣﺎﺷ عﻮﻧ

،ﻦﯾﺮﻤﺗ تﺪﺷ

،ﻦﯾﺮﻤﺗ تﺪﻣ

،ﻦﯾﺮﻤﺗ ﺮﺗاﻮﺗ تﺎﺴﻠﺟ ﯽﺷزرو رد

ﻪﺘﻔﻫ و لﻮﻃ تﻼﺧاﺪﻣ ﯽﺷزرو

و 4.

ﻦﯿﺘﭙﻟ ﺮﯾدﺎﻘﻣ شور و

هزاﺪﻧا ﮔﯿ ﺮ ي ﻦﯿﻨﭽﻤﻫ .نآ فاﺮﺤﻧا و ﻦﯿﮕﻧﺎﯿﻣ ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ مﺎﺠﻧا ياﺮﺑ

رد ﻦﯿﺘﭙﻟ ﺮﯾدﺎﻘﻣ دراﺪﻧﺎﺘﺳا ﻠﺣﺮﻣ

ﮥ ﭘﯿ ﺶ نﻮﻣزآ و ﺲﭘ ﻣزآ نﻮ فﻼﺘﺧا) تاﺮﯿﯿﻐﺗ ﻦﯿﮕﻧﺎﯿﻣ ﺎﯾ ﺲﭘ

نﻮﻣزآ ﺎﺑ ﭘﯿ ﺶ نﻮﻣزآ طﻮﺑﺮﻣ دراﺪﻧﺎﺘﺳا فاﺮﺤﻧا و (

،زﺎﯿﻧ ترﻮﺻ رد .ﺪﻧﺪﺷ جاﺮﺨﺘﺳا نآ ﻪﺑ هداد

ﺎﻫ ي زا هدﺎﻔﺘﺳا ﺎﺑ زﺎﯿﻧ درﻮﻣ مﺮﻧ

راﺰﻓا

Get data

جاﺮﺨﺘﺳا رادﻮﻤﻧ زا زﺎﯿﻧ ترﻮﺻ رد ﻦﯿﻨﭽﻤﻫ .ﺪﻧﺪﺷ

1 . Cochrane

2. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)

(6)

76

رﺎﻬﺑ ،لوا ةرﺎﻤﺷ ،ﻢﻫدﺰﻧﺎﭘ ةرود ،ﯽﺷزرو ﯽﺘﺴﯾز مﻮﻠﻋ 1402

هداد ﺎﻫ ي ﯽﮐرﺎﭼ فاﺮﺤﻧا ،ﻪﻧﺎﯿﻣ ﺮﯾدﺎﻘﻣ زا زﺎﯿﻧ درﻮﻣ .ﺪﻧﺪﺷ دروآﺮﺑ رﺎﯿﻌﻣ يﺎﻄﺧ و

هوﻼﻋ ﺮﺑ جاﺮﺨﺘﺳا ياﺮﺑ زﺎﯿﻧ ترﻮﺻ رد ،ﻦﯾا هداد

ﺎﻫ ﺎﺑ

ﺪﻨﺴﯾﻮﻧ ة ﺪﺷ ﻪﺒﺗﺎﮑﻣ تﻻﺎﻘﻣ ﻪﺑ طﻮﺑﺮﻣ لﻮﺌﺴﻣ )

رادﻮﻤﻧ 1(

.

ﯽﺑﺎﯾزرا ﺖﯿﻔﯿﮐ

تﺎﻌﻟﺎﻄﻣ

ﯽﺑﺎﯾزرا ﺖﯿﻔﯿﮐ تﺎﻌﻟﺎﻄﻣ هﺪﺷدراو ﻖﯿﻘﺤﺗ ﻪﺑ ﺮﺿﺎﺣ

ﺎﺑ هدﺎﻔﺘﺳا زا ﮏﭼ ﻟﯿ ﺖﺴ

Pedro

ﻂﺳﻮﺗ نﺎﮔﺪﻨﺴﯾﻮﻧ ﻪﺑ

ترﻮﺻ ﻞﻘﺘﺴﻣ ا مﺎﺠﻧ ﺖﻓﺮﮔ و

ﻪﻧﻮﮔﺮﻫ ﺾﻗﺎﻨﺗ و فﻼﺘﺧا ﺮﻈﻧ زا ﻖﯾﺮﻃ ﺪﻨﺴﯾﻮﻧ ﺎﺑ ترﻮﺸﻣ ة

ﻦﯾا .ﺪﺷ ﻞﺣ مﻮﺳ ﮏﭼ

ﻟﯿ ﺖﺴ ﻞﻣﺎﺷ 11 رﺎﯿﻌﻣ ﺖﺳا ﻪﮐ ﻌﻣ ﯿ ﺎﻫرﺎ ي رﻮﮐ ندﺮﮐ

ﺖﮐﺮﺷ نﺎﮔﺪﻨﻨﮐ و رﻮﮐ ندﺮﮐ ﻪﻠﺧاﺪﻣ ﺮﮔ ﻪﺑ ﻞﯿﻟد مﺪﻋ اﺮﺟا رد تﻼﺧاﺪﻣ ﯽﺷزرو

رﺎﻨﮐ ﺪﺷ ﻪﺘﺷاﺬﮔ )

13 ( . ﯽﺑﺎﯾزرا ﻦﯾاﺮﺑﺎﻨﺑ ﺖﯿﻔﯿﮐ

تﺎﻌﻟﺎﻄﻣ ﺎﺑ

هدﺎﻔﺘﺳا زا 9 رﺎﯿﻌﻣ ترﻮﺻ ﺖﻓﺮﮔ ﻪﮐ رد لوﺪﺟ 2 ﻪﺋارا هﺪﺷ ﺖﺳا .

ﻞﯿﻠﺤﺗاﺮﻓ فاﺪﻫا سﺎﺳا ﺮﺑ ﻖﯿﻘﺤﺗ

ﻞﻣﺎﺷ ﻞﻘﺘﺴﻣ ﻞﯿﻠﺤﺗ ود ﺮﺿﺎﺣ ﺛﺄﺗ

ﯿﺮ ﻪﺴﯾﺎﻘﻣ ﻦﯿﻨﭽﻤﻫ وHIIT

ﺛﺄﺗ ﯿﺮ ﺎﺑ ﯽﻣواﺪﺗ ﻦﯾﺮﻤﺗ ﺎﺑ HIIT

ﺮﺑ ﻂﺳﻮﺘﻣ تﺪﺷ

مﺎﺠﻧا ﻦﯿﺘﭙﻟ ﯽﺷدﺮﮔ ﺮﯾدﺎﻘﻣ ﺖﻓﺮﮔ

رد . صﻮﺼﺧ ﺛﺄﺗ

ﯿﺮ ياﺮﺑ .ﺪﻧﺪﺷ دراو هداد عﻮﻧ ود ﯽﻠﺒﻗ ﻞﯿﻠﺤﺗاﺮﻓ تﺎﻌﻟﺎﻄﻣ سﺎﺳا ﺮﺑ ،ﻦﯿﺘﭙﻟ ﺮﺑ HIIT

هوﺮﮔ ياراد ﻪﮐ ﯽﺗﺎﻌﻟﺎﻄﻣ ﺪﻧدﻮﺑ لﺮﺘﻨﮐ و HIIT

، هداد ﺎﻫ ي ﻪﺑ طﻮﺑﺮﻣ ﭘﯿ

ﺶ نﻮﻣزآ و ﺲﭘ نﻮﻣزآ تﺎﻌﻟﺎﻄﻣ ياﺮﺑ .ﺪﻧﺪﺷ دراو هوﺮﮔ ود ﺮﻫ

ﮏﺗ ﯽﻫوﺮﮔ ﺎﻬﻨﺗ ﮥﺴﯾﺎﻘﻣ ﺲﭘ نﻮﻣزآ ﺮﺑاﺮﺑ رد ﭘﯿ ﺶ نﻮﻣزآ هوﺮﮔ ياﺮﺑ .ﺪﻧﺪﺷ ﻞﯿﻠﺤﺗاﺮﻓ دراوHIIT

ةزاﺪﻧا ﮥﺒﺳﺎﺤﻣ ﺮﯾدﺎﻘﻣ ،ﺮﺛا

وSMD

ﮥﻠﺻﺎﻓ

نﺎﻨﯿﻤﻃا 95 ﺪﺻرد

(CIs)

زا هدﺎﻔﺘﺳا ﺎﺑ شور

لﺪﻣ ﺮﺛا ﯽﻓدﺎﺼﺗ ﻪﺒﺳﺎﺤﻣ .ﺪﺷ ﻪﺑ رﻮﻈﻨﻣ ﯽﺳرﺮﺑ نﻮﻣزآ زا ،تﺎﻌﻟﺎﻄﻣ ﺲﻧﺎﺠﺗ مﺪﻋ ﺎﯾ ﯽﻧﻮﮕﻤﻫﺎﻧ

I2

ا هدﺎﻔﺘﺳ ﺪﺷ ﻪﮐ ﯿﻠﺤﺗ ﻞ ﺮﯾدﺎﻘﻣ ﯽﻧﻮﮕﻤﻫﺎﻧ ﺮﺑ

سﺎﺳا ﻞﻤﻌﻟارﻮﺘﺳد ﺮﯾدﺎﻘﻣ ﻪﮐ ﺖﻓﺮﮔ ترﻮﺻ ناﺮﮐﻮﮐ

I2

زا ﺮﺘﻤﮐ 25

،ﻒﯿﻔﺧ ﯽﻧﻮﮕﻤﻫﺎﻧ ﺪﺻرد

زا ﺮﺘﺸﯿﺑ 25 زا ﺮﺘﺸﯿﺑ ،ﻢﮐ ﯽﻧﻮﮕﻤﻫﺎﻧ ﺪﺻرد 50

زا ﺮﺘﺸﯿﺑ و ﻂﺳﻮﺘﻣ ﯽﻧﻮﮕﻤﻫﺎﻧ ﺪﺻرد 75

ﺪﺻرد ﯽﻧﻮﮕﻤﻫﺎﻧ ﻻﺎﺑ

ﯽﻣ نﺎﺸﻧ ار داد

. ﻪﺑ رﻮﻈﻨﻣ

ﯽﺳرﺮﺑ يﺮﯿﮔﻮﺳ رﺎﺸﺘﻧا

زا ﻞﯿﻠﺤﺗ ﻧﻮﻓ يﺮﺼﺑ ﻞ

تﻼﭘ و1

ﮥﺠﯿﺘﻧ ﺖﺴﺗ

Egger

هدﺎﻔﺘﺳا ﺪﺷ ﻪﮐ ﺢﻄﺳ ﺎﻨﻌﻣ راد ي 01 /0

<

ﺮﻈﻧ رد P

ﺪﺷ ﻪﺘﻓﺮﮔ

) 13 ( ﺎﻤﺗ . م نﻮﻣزآ ﺎﻫ ي يرﺎﻣآ ﺎﺑ هدﺎﻔﺘﺳا زا

2

.ﺖﻓﺮﮔ ترﻮﺻCMA

ﯾ ﻪﺘﻓﺎ ﺎﻫ ي ﺶﻫوﮋﭘ

ﺞﯾﺎﺘﻧ ﺖﺴﺟ ﻮﺟو

عﻮﻤﺠﻣ رد 670

زا ﻪﻟﺎﻘﻣ ﺖﺴﺟ ﻮﺟو ي مﺎﻈﻧ ﺪﻨﻣ دراو ﻦﯾﺮﮑﺳا مﺎﺠﻧا ياﺮﺑ ﻪﮐ ﺪﻧﺪﺷ جﺮﺨﺘﺴﻣ مﺮﻧ

راﺰﻓا

End Note

ﻪﺨﺴﻧ 20 ﺷ زا ﺲﭘ .ﺪﻧﺪ

،يراﺮﮑﺗ تﻻﺎﻘﻣ فﺬﺣ 528

ﺖﯾﺎﻬﻧ رد ﻪﮐ ﺪﻧﺪﺷ ﻪﯿﻟوا ﻦﯾﺮﮑﺳا دراو ﻪﻟﺎﻘﻣ 432

اﻮﻨﻋ ﯽﺳرﺮﺑ زا ﺲﭘ ﻪﻟﺎﻘﻣ .ﺪﻧﺪﺷ فﺬﺣ هﺪﯿﮑﭼ و ن

ﺑ زا ﯿ ﻦ 96

ﻟﺎﻘﻣ ﮥ ﻗﺎﺑ ﯽ ﺎﻣ هﺪﻧ 74 ﻞﯾﻻد ﻪﺑ ﻪﻟﺎﻘﻣ هﺪﺷﺮﮐذ

رادﻮﻤﻧ رد 1

ﺖﯾﺎﻬﻧ رد .ﺪﻧﺪﺷ فﺬﺣ 22

ﺮﻓ دراو ﻪﻌﻟﺎﻄﻣ رادﻮﻤﻧ) ﺪﺷ ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗا

1 .(

ﯽﮔﮋﯾو ﻧدﻮﻣزآ ﯽ ﺎﻫ

عﻮﻤﺠﻣ رد 545

ﯽﻧدﻮﻣزآ زا 22 ﻪﻌﻟﺎﻄﻣ داﺮﻓا .ﺪﻧﺪﺷ ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ دراو رد ﺮﺿﺎﺣ

رﺎﻤﯿﺑ ﻞﻣﺎﺷ ﻖﯿﻘﺤﺗ ﺮﻣ و نز ﯽﺘﺑﺎﯾد نا

داﺪﻌﺗ ﻪﺑ د 87

د داﺮﻓا ،ﺮﻔﻧ و ﻪﻓﺎﺿا يارا

داﺪﻌﺗ ﻪﺑ (دﺮﻣ و نز) نز 183

ﺪﻧدﻮﺑ ﺮﻔﻧ ﻦﯿﻨﭽﻤﻫ . 85

ياراد نز ﺑﯿ

رﺎﻤ ي ﺎﻫ ي رﺪﻨﺳ و ناﺪﻤﺨﺗ م ﯽﻠﭘ

ﮏﯿﺘﺴﯿﮐ و

ﻼﺘﺒﻣ

ﻪﻨﯿﺳ نﺎﻃﺮﺳ ﻪﺑ ﺪﻧدﻮﺑ

. ﮥﻨﻣاد ﯽﻨﺳ ﻧدﻮﻣزآ ﯽ ﺎﻫ ﺮﻘﺗ ﯾًﺎﺒ 15 ﺎﺗ 61 و لﺎﺳ ﮥﻨﻣاد ﺎﻬﻧآ BMI

ﺮﻘﺗ ﯾًﺎﺒ 23 ﺗ ﺎ 36 .دﻮﺑ ﻊﺑﺮﻣ ﺮﺘﻣ ﺮﺑ مﺮﮔﻮﻠﯿﮐ

ﻧدﻮﻣزآ ﯽ ﺎﻫ ي هﺪﺷدراو ﺑ ﻪ ﻖﯿﻘﺤﺗ رو ﺖﯿﻟﺎﻌﻓ رد تﻼﺧاﺪﻣ عوﺮﺷ زا ﺶﯿﭘ ﺮﺿﺎﺣ ز

ﻧدﻮﺑ هدﺮﮑﻧ ﺖﮐﺮﺷ ﻢﻈﻨﻣ ﯽﺷ .ﺪ

1. Funnel plot

(7)

ﯿﺘﭙﻟ حﻮﻄﺳ ﺮﺑ ﻻﺎﺑ تﺪﺷ ﺎﺑ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ ﺮﯿﺛﺄﺗ يرﺎﻤﯿﺑ نوﺪﺑ و ﺎﺑ داﺮﻓا ﺮﺑ ﯽﺷدﺮﮔ ﻦ

... ﻦﻣﺰﻣ يﺎﻫ

77

ﻞﮑﺗوﺮﭘ ﺎﻫ ي ﻦﯾﺮﻤﺗ

تﺎﯿﺋﺰﺟ ﻞﻣﺎﮐ ﻞﮑﺗوﺮﭘ ﺎﻫ ي ﻦﯾﺮﻤﺗ رد لوﺪﺟ 1 ﻪﺋارا هﺪﺷ تﺎﻌﻟﺎﻄﻣ مﺎﻤﺗ .ﺖﺳا هﺪﺷدراو

ﺮﭘ زا ﺮﺿﺎﺣ ﻖﯿﻘﺤﺗ ﻪﺑ و

ﻞﮑﺗ هدﺮﮐ هدﺎﻔﺘﺳا HIIT

ﺪﻧدﻮﺑ زا ﯽﺷزرو تﻼﺧاﺪﻣ لﻮﻃ . ود

ﺎﺗ ﻪﺘﻔﻫ ﺶﺷ ﺑ هﺎﻣ زا تﺎﻌﻟﺎﻄﻣ ﯽﻣﺎﻤﺗ .ﺖﺷاد تﺎﻌﻟﺎﻄﻣ ﻦﯿﺑ رد ار راﺮﮑﺗ ﻦﯾﺮﺘﺸﯿﺑ ﻪﺘﻔﻫ ﺖﺸﻫ ﻪﮐ دﻮ ﻪﺳ

.ﺪﻧدﻮﺑ هدﺮﮐ هدﺎﻔﺘﺳا ﻪﺘﻔﻫ رد ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ ﻪﺴﻠﺟ

رادﻮﻤﻧ 1 . ﻮﻠﻓ ترﺎﭼ ﺖﺴﺟ ﻮﺟو

(8)

يرﺎﻤﯿﺑ نوﺪﺑ و ﺎﺑ داﺮﻓا ﺮﺑ ﯽﺷدﺮﮔ ﻦﯿﺘﭙﻟ حﻮﻄﺳ ﺮﺑ ﻻﺎﺑ تﺪﺷ ﺎﺑ ﯽﺑوﺎﻨﺗ ﻦﯾﺮﻤﺗ ﺮﯿﺛﺄﺗ ... ﻦﻣﺰﻣ يﺎﻫ

78

لوﺪﺟ 1 . ﯽﻧدﻮﻣزآ ﯽﮔﮋﯾو ﻞﮑﺗوﺮﭘ و ﺎﻫ

ﻦﯾﺮﻤﺗ يﺎﻫ

(9)

79

ﻞﯿﻠﺤﺗاﺮﻓ ﺛﺄﺗ ﯿ ﺮ ﻦﯿﺘﭙﻟ ﺮﺑHIIT

ﺰﯿﻟﺎﻧآ هداد ﺎﻫ ي 26 ﻠﺧاﺪﻣ ﻞﻣﺎﺷ ﻪ 335 هوﺮﮔ رد ﯽﻧدﻮﻣزآ و HIIT

105 لﺮﺘﻨﮐ هوﺮﮔ رد ﯽﻧدﻮﻣزآ ﺦﯾرﺎﺗ زا

2013 ﺎﺗ 2021 نﺎﺸﻧ داد ﻪﮐ

ﻪﺑHIIT

ﺶﻫﺎﮐ ﺎﻨﻌﻣ راد ي ﻦﯿﺘﭙﻟ ﯽﻣﺮﺳ ] 008 /0

=

)،P

07 /0 - ﺎﺗ 48 /0

- :

(CI

28 / 0 [-

ﺮﺠﻨﻣ ﻣ ﯽ دﻮﺷ رادﻮﻤﻧ) 1 ( ﺎﺑ . هدﺎﻔﺘﺳا زا نﻮﻣزآ

I2

ﯽﻧﻮﮕﻤﻫﺎﻧ ﯽﺳرﺮﺑ

ﺪﺷ و نﺎﺸﻧ ﺞﯾﺎﺘﻧ داد

ﻪﮐ ﺎﻧ ﯽﻧﻮﮕﻤﻫ ﯽﯾﻻﺎﺑ دﻮﺟو دراد ) 001 /0

= P

33,

/ 59

2=

.( I

يﺮﺼﺑ ﻞﯿﻠﺤﺗ ﺎﺑ رﺎﺸﺘﻧا يﺮﯿﮔﻮﺳ ﯽﺳرﺮﺑ

،دراد دﻮﺟو رﺎﺸﺘﻧا يﺮﯿﮔﻮﺳ ﻪﮐ داد نﺎﺸﻧ تﻼﭘ ﻞﻧﻮﻓ ﻟﺎﺣرد

ﯽ ﻪﮐ ﺖﺴﺗ ﺞﯾﺎﺘﻧ

Egger

ار نآ ﺄﺗ ﯿﯾ ﺪ ) دﺮﮑﻧ 16 /0 .(P=

ﻞﯿﻠﺤﺗ ﺖﯿﺳﺎﺴﺣ نﺎﺸﻧ

ﺎﺑ،داد هدﺎﻔﺘﺳا زا فﺬﺣ ﻪﺑ ﮏﺗ ﮏﺗ

،تﺎﻌﻟﺎﻄﻣ ﺖﻬﺟ

ناﺰﯿﻣ و ةزاﺪﻧا ﺮﺛا ﺮﯿﯿﻐﺗ .دﺮﮑﻧ ي

(10)

80 ﻠﻋ

رﺎﻬﺑ ،لوا ةرﺎﻤﺷ ،ﻢﻫدﺰﻧﺎﭘ ةرود ،ﯽﺷزرو ﯽﺘﺴﯾز مﻮ 1402

ﻦﯿﺘﭙﻟﺮﺑHIITﺮﺛاطﻮﺑﺮﻣ (Forest Plot )ﺖﺷﺎﺒﻧارادﻮﻤﻧ.2رادﻮﻤﻧ

ﮥﺴﯾﺎﻘﻣ ﺛﺄﺗ

ﯿ ﺮ ﺎﺑHIIT ﻦﯿﺘﭙﻟ ﺮﺑMICT

ﺰﯿﻟﺎﻧآ هداد ﺎﻫ ي 9 ﻪﻠﺧاﺪﻣ ﻞﻣﺎﺷ 99 هوﺮﮔ رد ﯽﻧدﻮﻣزآ وHIIT

93 هوﺮﮔ رد ﯽﻧدﻮﻣزآ ﺦﯾرﺎﺗ زاMICT

2015 ﺎﺗ 2021 ﻪﮐ داد نﺎﺸﻧ توﺎﻔﺗ

ﺎﻨﻌﻣ راد ي ﻦﯿﺑ

IT

وHI

دراﺪﻧ دﻮﺟو ﻦﯿﺘﭙﻟ ﯽﺷدﺮﮔ ﺮﯾدﺎﻘﻣ ﺮﺑ MICT

] 82 /0

=

)،P

27 /0 ﺎﺗ 34 /0

- :

(CI

03 / 0 رادﻮﻤﻧ) [-

2 ( . ﺎﺑ هدﺎﻔﺘﺳا زا

نﻮﻣزآ

I2

ﯽﻧﻮﮕﻤﻫﺎﻧ ﯽﺳرﺮﺑ

ﺪﺷ و نﺎﺸﻧ ﺞﯾﺎﺘﻧ داد

ﻪﮐ ﯽﻧﻮﮕﻤﻫﺎﻧ ﺎﻨﻌﻣ

راد ي دراﺪﻧ دﻮﺟو )

33 /0

= P

06,

/ 12

2=

.(I

ﺎﺑ رﺎﺸﺘﻧا يﺮﯿﮔﻮﺳ ﯽﺳرﺮﺑ

ﮐ داد نﺎﺸﻧ تﻼﭘ ﻞﻧﻮﻓ يﺮﺼﺑ ﻞﯿﻠﺤﺗ ،دراد دﻮﺟو رﺎﺸﺘﻧا يﺮﯿﮔﻮﺳ ﻪ

ﻟﺎﺣرد ﯽ ﻪﮐ ﺖﺴﺗ ﺞﯾﺎﺘﻧ

Egger

ار نآ ﺄﺗ ﯿﯾ ﺪ ) دﺮﮑﻧ 46 /0 .(P=

ﻞﯿﻠﺤﺗ

ﺖﯿﺳﺎﺴﺣ نﺎﺸﻧ

داد ﺎﺑ هدﺎﻔﺘﺳا زا فﺬﺣ ﻪﺑ ﮏﺗ ﮏﺗ

،تﺎﻌﻟﺎﻄﻣ ﺖﻬﺟ ناﺰﯿﻣ و ةزاﺪﻧا ﺮﺛا ﺮﯿﯿﻐﺗ .دﺮﮑﻧ ي

(11)

81

رادﻮﻤﻧ 3 . رادﻮﻤﻧ ) ﺖﺷﺎﺒﻧا Forest Plot (

طﻮﺑﺮﻣ ﮥﺴﯾﺎﻘﻣ ﺎﺑHIIT

ﻦﯿﺘﭙﻟ ﺮﺑMICT

ﻠﺤﺗ ﯿ ﻞ زﯾ ﻫوﺮﮔﺮ ﯽ

هوﺮﮔ ود ﺮﻫ) عﻮﻤﺠﻣ رد (لﺮﺘﻨﮐ وHIIT

295 رد ﯽﻧدﻮﻣزآ زﯾ

هوﺮﮔﺮ و ﻦﻣﺰﻣ نارﺎﻤﯿﺑ 138

رد ﯽﻧدﻮﻣزآ زﯾ

ﮔﺮ هوﺮ ﻦﻣﺰﻣ يرﺎﻤﯿﺑ ﺪﻗﺎﻓ داﺮﻓا

.ﺖﻓﺮﮔ راﺮﻗ ﺞﯾﺎﺘﻧ

ﻞﯿﻠﺤﺗ ﯽﻫوﺮﮔﺮﯾز سﺎﺳا ﺮﺑ

ﯽﺘﻣﻼﺳ ﺖﯿﻌﺿو ﻧدﻮﻣزآ

ﯽ ﺎﻫ د نﺎﺸﻧ دا ﻪﮐ ﺶﻫﺎﮐ ﻪﺑ HIIT

ﺎﻨﻌﻣ راد ﺎﺑ داﺮﻓا رد ﻦﯿﺘﭙﻟ

ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻣ ﻦﻣﺰ ﺮﺠﻨﻣ ﻣ ﯽ دﻮﺷ ] 001 /0

، )P=

19 /0 - ﺎﺗ 68 /0

CI: -

( 44 / 0 [ -

ﻟﺎﺣرد ﯽ ﻪﮐ ﻓ داﺮﻓا رد ﺪﻗﺎ ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﺎﻨﯾﺮﻤﺗ عﻮﻧ ﻦﯾا ﻦﻣﺰﻣ ت

تاﺮﯿﺛﺄﺗ ﺎﻨﻌﻣ راد ي ﺖﺷاﺪﻧ ] 93 /0

، )P=

32 /0 ﺎﺗ 30 /0

CI: -

( 01 /0 [.

تﺎﻌﻟﺎﻄﻣ ﺖﯿﻔﯿﮐ ﺎﺑ تﺎﻌﻟﺎﻄﻣ ﺖﯿﻔﯿﮐ ﯽﺳرﺮﺑ ﮏﭼ

ﻟﯿ ﺖﺴ

PEDRO

لوﺪﺟ رد 2

ا ﻦﯾا ﺮﺑ .ﺖﺳا هﺪﺷ ﻪﺋارا تﺎﻌﻟﺎﻄﻣ ،سﺎﺳ

هﺪﺷدراو د ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ ﻪﺑ يارا

ﻦﯿﺑ زﺎﯿﺘﻣا 3

ﺎﺗ 7 .ﺪﻧدﻮﺑ

لوﺪﺟ 2 . درﻮﻣ تﺎﻌﻟﺎﻄﻣ ﺖﯿﻔﯿﮐ ﯽﺑﺎﯾزرا ﻖﯿﻘﺤﺗ رد ﯽﺳرﺮﺑ

9 8 7 6 5 4 3 2 1 لﺎﺳ- ﻪﻌﻟﺎﻄﻣ

Point Measure

ﻞﯿﻠﺤﺗ ﻦﯿﺑ ﻫوﺮﮔ

ي

Intention to treat

(ITT )

85%

ﻧدﻮﻣزآ ﯽ

ﺎﻫ Assessors

blind

نﺎﺴﮑﯾ رد ندﻮﺑ ﭘﯿ ﺶ نﻮﻣزآ

ندﻮﺑ نﺎﻬﻨﭘ ﯽﻓدﺎﺼﺗ

ﯽﻓدﺎﺼﺗ

ندﻮﺑ دورو رﺎﯿﻌﻣ

✓ ✓ × ✓ × × × × ✓

و شﺎﺘﮐآ ،نارﺎﮑﻤﻫ 2019

) 14 (

✓ ✓ × ✓ × ✓ × ✓ ✓

و ﮓﻨﯿﻨﻤﻟآ ،نارﺎﮑﻤﻫ 2015

) 15 (

✓ ✓ × ✓ × ✓ × ✓ ✓

و رﻮﭘ ضﻮﻋ نارﺎﮑﻤﻫ

، 2021

) 16 (

✓ ✓ × ✓ × ✓ × ✓ ✓ 2020 ،ﯽﯾﺎﺑﺎﺑ

) 17 (

(12)

82 ﻠﻋ

رﺎﻬﺑ ،لوا ةرﺎﻤﺷ ،ﻢﻫدﺰﻧﺎﭘ ةرود ،ﯽﺷزرو ﯽﺘﺴﯾز مﻮ 1402

× ✓ × ✓ × ✓ × ✓ ✓ ، ﯽﺴﻧﺮﻘﻣ و ماﺮﻬﺑ

2012 ) 18 (

✓ ✓ × ✓ ✓ ✓ × ✓ ✓

و ﺮﺷﻮﻠﺑ ،نارﺎﮑﻤﻫ 2017

) 19 (

× ✓ × ✓ × ✓ × ? ✓

و ﺎﯾرﺪﻟﺎﮐ نارﺎﮑﻤﻫ

، 2018

) 20 (

× ✓ × ✓ × × × ✓ ✓

و ﺪﻟاﻮﻧود نارﺎﮑﻤﻫ

، 2019

) 21 (

✓ ✓ × ✓ × ✓ × ✓ ✓

و ﺎﺳوﺮﮔ نارﺎﮑﻤﻫ ،

2019 )2 2(

× ✓ × × × ✓ × ✓ ✓

و نﻮﺘﺴﯿﻫ نارﺎﮑﻤﻫ ، 20 20

) 23 (

✓ ✓ × ✓ × × × ✓ ✓

ﺪﻨﻤﺷﻮﻫ و مﺪﻘﻣ

ﮑﻤﻫ ،نارﺎ 2021

) 24 (

✓ ✓ × ✓ × ✓ × ✓ ✓

يراﻮﻧﺎﺧ و

نارﺎﮑﻤﻫ ، 2019

) 25 (

✓ ✓ × ✓ × ✓ × ✓ ✓

ﮓﻨﮐ و

،نارﺎﮑﻤﻫ 2016

) 26 (

✓ ✓ × ✓ ✓ × × ✓ ✓

ﻨﮐ و ﮓ

،نارﺎﮑﻤﻫ 2017

) 26 (

✓ ✓ × ✓ × × × ✓ ✓

و ﺎﮑﺳﻮﻟﺰﮐ ارﺎﮑﻤﻫ ،ن 2021

) 27 (

✓ ✓ × ✓ × ✓ ✓ ✓ ✓ ،نارﺎﮑﻤﻫ و ﯽﻟ

2015 ) 28 (

✓ ✓ × ✓ × ✓ × ? ✓

و ﺖﯿﮕﻟ ،نارﺎﮑﻤﻫ 2012

) 29 (

✓ ✓ × ؟ × × × ? ✓

و ﻦﺳﺪﻣ ارﺎﮑﻤﻫ ،ن 2015

) 30 (

✓ ✓ × ✓ × ✓ × ✓ ✓

داﮋﻧ ﯽﮑﻟﺎﻣ و

نارﺎﮑﻤﻫ ، 2019

) 31 (

✓ ✓ × ✓ × ✓ × ✓ ✓

و ﮏﯿﺒﻟﺪﯿﻣ ،نارﺎﮑﻤﻫ 2021

) 32 (

(13)

83

✓ ✓ × ✓ × ? × ✓ ✓

و ﯽﯾﺎﺿر ،نارﺎﮑﻤﻫ 2013

) 33 (

✓ ✓ × ✓ × ✓ × ✓ ✓

و نﺎﯿﺒﯿﺗﺮﺗ ،نارﺎﮑﻤﻫ 2016

) 34 (

✓ ✓ × ✓ × ✓ × ✓ ✓

رذآ ﯽﻋﻮﻠﻃ و

ارﺎﮑﻤﻫ ،ن 2018

) 35 (

و ﺚﺤﺑ ﺘﻧ ﯿ ﻪﺠ ﮔﯿ ﺮ ي

و ﯽﮑﯿﻟﻮﺑﺎﺘﻣ تﻻﻼﺘﺧا ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﻦﯿﺘﭙﻟ ﯽﻧﻮﺧ شدﺮﮔ ﺮﯾدﺎﻘﻣ ﺶﯾاﺰﻓا ﻪﺑ ﻦﻣﺰﻣ ﺮﺠﻨﻣ

ﻣ ﯽ دﻮﺷ ﻞﻗاﺪﺣ ﻪﮐ ، ﯽﺸﺨﺑ رد

ﻣ ﻣ ﻪﺑ طﻮﺑﺮ ﺖﻣوﺎﻘ

و ﺪﻨﯾاﺮﻓ ﻦﯾا دﻮﺒﻬﺑ ﻪﺑ ﺮﺠﻨﻣ ﺖﺳا ﻦﮑﻤﻣ ﯽﺷزرو تﺎﻨﯾﺮﻤﺗ ،ﻦﯾا دﻮﺟو ﺎﺑ .ﺖﺳا ﯽﻨﯿﺘﭙﻟ ﻪﺑ

ﺶﻫﺎﮐ نآ لﺎﺒﻧد ﻮﻫ ﻦﯾا

ﺧ رد نﻮﻣر ﻦﯾا ﺮﺑ .دﻮﺷ نﻮ

ﻪﮐ داد نﺎﺸﻧ ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ ﺞﯾﺎﺘﻧ ،سﺎﺳا يﺮﯿﮕﻤﺸﭼ تاﺮﯿﺛﺄﺗ HIIT

،دراد ﻦﯿﺘﭙﻟ ﺶﻫﺎﮐ ﺮﺑ ﻟﺎﺣرد

ﯽ ﻪﮐ ﺗوﺎﻔﺗ ﯽ ﻞﮑﺗوﺮﭘ ﻦﯿﺑ ﺎﺑ HIIT

.ﺪﺸﻧ هﺪﻫﺎﺸﻣMICT

هوﻼﻋ ﺮﺑ ،ﻦﯾا ﻢﻬﻣ ﺮﺗ ﯾ ﻦ ﯾ ﻪﺘﻓﺎ ﺎﻫ ي ﻪﮐ دﻮﺑ نآ زا ﯽﮐﺎﺣ ،ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ ﻘﻣ HIIT

داﺮﻓا رد ار ﻦﯿﺘﭙﻟ ﯽﻧﻮﺧ شدﺮﮔ ﺮﯾدﺎ

ﺎﺑ ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻦﻣﺰﻣ ﺶﻫﺎﮐ ﻣ ﯽ ﺪﻫد ، ﻟﺎﺣرد ﯽ ﻪﮐ ﺶﻫﺎﮐ ﻢﻟﺎﺳ داﺮﻓا رد نﺎﯾﺎﺷ

ﺘﻧ ﻦﯾا .ﺪﺸﻧ هﺪﻫﺎﺸﻣ ﻪﺟﻮﺗ داﺪﻌﺗ زا ﺞﯾﺎ

545 ﻪﮐ ﯽﻧدﻮﻣزآ ﺮﻔﻧ

203 ﺮﻔﻧ ﻪﺑ ﻼﺘﺒﻣ ﺎﻬﻧآ زا ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﻪﻠﻤﺟ زا ﻦﻣﺰﻣ ﺑﯿ

رﺎﻤ ي ﺎﻫ ي ﯽﺒﻠﻗ و ﯽﮑﯿﻟﻮﺑﺎﺘﻣ -

ﺪﻧدﻮﺑ ﯽﻗوﺮﻋ ﺑﻪ

ﺖﺳد .ﺪﻣآ

رد لﺎﺳ ﺎﻫ ي ﺮﺑ ﯽﺻﺎﺧ ﺰﮐﺮﻤﺗ ﺮﯿﺧا ﻓ ﻪﮐ ﻪﺘﻓﺮﮔ ترﻮﺻHIIT

ﻞﯿﻠﺤﺗاﺮ شراﺰﮔ ﯽﻠﺒﻗ يﺎﻫ هدﺮﮐ

ﺪﻧا تﺎﻨﯾﺮﻤﺗ عﻮﻧ ﻦﯾا ﻪﮐ تاﺮﯿﺛﺄﺗ

يﺪﯿﻔﻣ

ﺶﻫﺎﮐ ﺮﺑ ةدﻮﺗ

ﯽﺑﺮﭼ ﻪﺑ وﯾ هﮋ ﯽﺧﺮﺑ دﻮﺒﻬﺑ ،ﺪﺒﮐ و ﯽﯾﺎﺸﺣا ﯽﺑﺮﭼ يﺎﻫﺮﮕﻧﺎﺸﻧ

دﻮﺒﻬﺑ و ﯽﺑﺎﻬﺘﻟا ﺺﺧﺎﺷ

ﺎﻫ ي دراد ﯽﻤﺴﯾﻼﮔ )

36 ( دﻮﺟو ﺎﺑ .

رﺎﺛآ ،ﻦﯾا ردHIIT

ﻞﯿﻠﺤﺗاﺮﻓ يﺎﻫ .ﺖﺳا هﺪﺷ ﯽﺳرﺮﺑ ﺮﺘﻤﮐ ﯽﻠﺒﻗ رد ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ ﺞﯾﺎﺘﻧ

ﮥﻨﯿﻣز راﺬﮔﺮﺛا ي ،ﯽﺷزرو ﻦﯾﺮﻤﺗ فﺮﺻ

ﺮﻈﻧ عﻮﻧ زا

ﺎﺑ ،ﻦﯾﺮﻤﺗ ﯾ

ﻪﺘﻓﺎ ﺎﻫ ي ﻞﯿﻠﺤﺗاﺮﻓ دراد ﯽﻧاﻮﺨﻤﻫ ﯽﻠﺒﻗ يﺎﻫ )

8

، 9 ، 12 (.

ﻦﯿﻤﻫ رد صﻮﺼﺧ

تﻼﺧاﺪﻣ ﻪﮐ ﺪﻧدﺮﮐ شراﺰﮔ نارﺎﮑﻤﻫ و ﯽﻔﻠﺧ

و ﯽﺷزرو ﺬﻐﺗ

ﯾﻪ ا ي ﻦﯿﺘﭙﻟ ﯽﺷدﺮﮔ حﻮﻄﺳ ﺶﻫﺎﮐ ﻪﺑ ﺮﺠﻨﻣ

ﻣ ﯽ دﻮﺷ لﺎﺣ ﻦﯾا ﺎﺑ ، تﻼﺧاﺪﻣ

ﺬﻐﺗ ﯾﻪ ا ي ﺎﻔﯾا تاﺮﯿﯿﻐﺗ ﻦﯾا رد يرﻮﺤﻣ ﺶﻘﻧ

ﻣ ﯽ ﺪﻨﮐ . ﻪﺑ ﺮﻈﻧ ﻣ ﯽ ﺪﺳر نﺪﺑ نزو ﺶﻫﺎﮐ ﻪﮐ ﻪﺑ

وﯾ هﮋ ﺪﺷﺎﺑ ﻦﯿﺘﭙﻟ تاﺮﯿﯿﻐﺗ رد ﻢﻬﻣ ﻞﻣﺎﻋ ﺖﺳا ﻦﮑﻤﻣ ﯽﺑﺮﭼ هدﻮﺗ ﺶﻫﺎﮐ )

37 ( رد ﻦﯿﻨﭽﻤﻫ .

ﮥﻨﯿﻣز ﺮﺛا ،ﻦﯿﺘﭙﻟ ﺮﺑ HIIT

ﮥﻌﻟﺎﻄﻣ ﻗ ﻞﯿﻠﺤﺗاﺮﻓ ﺑ داﺮﻓا رد ﺎﻣ نارﺎﮑﻤﻫ ﻂﺳﻮﺗ ﯽﻠﺒ

ﺎ ﯽﮑﯿﻟﻮﺑﺎﺘﻣ تﻻﻼﺘﺧا تاﺮﯿﺛﺄﺗ

شراﺰﮔ ار يﺪﯿﻔﻣ هدﺮﮐ

ﺪﻧا

) 12 ((.

تﻻﺎﻘﻣ ﻦﯿﻨﭽﻤﻫ و ﯽﮑﯿﻟﻮﺑﺎﺘﻣ تﻻﻼﺘﺧا ﺎﺑ داﺮﻓا ،تﺎﻌﻟﺎﻄﻣ ﻢﮐ داﺪﻌﺗ ﻪﺑ دوﺪﺤﻣ ﯽﻠﺒﻗ ﻞﯿﻠﺤﺗاﺮﻓ لﺎﺣ ﻦﯾا ﺎﺑ پﺎﭼ

هﺪﺷ تﻼﺠﻣ رد

.دﻮﺑ ﯽﺴﯿﻠﮕﻧا ﯾ

ﻪﺘﻓﺎ ﺎﻫ ي شﺮﺘﺴﮔ ﻪﺑ ﺮﺠﻨﻣ ،ﺮﺿﺎﺣ ﻞﯿﻠﺤﺗاﺮﻓ ﯾ

ﻪﺘﻓﺎ ﺎﻫ ي ﺷ ﯽﻤﻬﻣ ﯽﻨﯿﻟﺎﺑ ﻦﯾا رد .دﻮﺑ هﺪﺸﻧ كرد ﯽﻠﺒﻗ تﺎﻌﻟﺎﻄﻣ رد ﻪﮐ ﺪ

ﻖﯿﻘﺤﺗ ﻪﺑ حﻮﺿو ﻪﮐ ﺪﺷ ﺺﺨﺸﻣ ﺎﺑ داﺮﻓا ردHIIT

ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻦﯿﺘﭙﻟ دﻮﺒﻬﺑ ﻪﺑ ﻦﻣﺰﻣ ﺮﺠﻨﻣ

ﻣ ﯽ دﻮﺷ ﯽﻨﯿﻟﺎﺑ ظﺎﺤﻟ زا ﻪﮐ ﻣ

ﯽ ﺪﻧاﻮﺗ ﺰﺋﺎﺣ رﺎﯿﺴﺑ

.ﺪﺷﺎﺑ ﺖﯿﻤﻫا ﻘﺤﺗ

ﯿ تﺎﻘ ناواﺮﻓ نﺎﺸﻧ هداد ﺪﻧا ﻪﮐ ﻗﺎﭼ ﯽ و ﻪﻓﺎﺿا نزو ﺐﺟﻮﻣ زوﺮﺑ ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻧﻮﮔﺎﻧﻮﮔ ﯽ نﻮﭽﻤﻫ رﺎﺸﻓﺮﭘ ﻧﻮﺧ ﯽ

، دﯾ ﺖﺑﺎ عﻮﻧ

2،

زوﺮﻠﮑﺳاوﺮﺗآ

، اﺰﻓا ﯾ ﺶ ﻼﺘﺑا ﻪﺑ ژﺮﻟآ ي ﻒﻌﺿ ، رد ﻣﺮﺗ ﯿ ﻢ ﺰﯿﻧ و ﺖﺣاﺮﺟ ﺳ

ﯿ ﻢﺘﺴ ﺒﺼﻋ ﯽ - ﻧﻮﻣرﻮﻫ ﯽ ﻣ ﯽ دﻮﺷ ) 38 (.

ﯾﮑ ﯽ زا ﻢﻬﻣ ﺮﺗ ﯾ ﻦ ﻻد ﯾ ﻞ رﺎﺛآ ﻗﺎﭼ ﯽ و ﻪﻓﺎﺿا نزو ار ﻪﺑ اﺰﻓا ﯾ ﺶ ةدﻮﺗ ﺑﺮﭼ ﯽ نﺪﺑ و اﺰﻓا ﯾ ﺶ ﺖﻈﻠﻏ ﻣﺮﺳ ﯽ ﺘﭙﻟ ﯿ ﻦ ﺖﺒﺴﻧ ﻣ ﯽ ﺪﻨﻫد ﺪﻫاﻮﺷ .

زﯾ دﺎ ي دﻮﺟو دراد ﻪﮐ نﺎﺸﻧ ﻣ ﯽ ﺪﻫد اﺰﻓا ﯾ ﺶ ﺳﺎﺴﺣ ﯿ ﺖ ﺘﭙﻟ ﯿ ﻦ ﺐﺟﻮﻣ ﻟﻮﺗ ﯿﺪ ﯾ ﮏ ﺗﻮﻨﻓ ﯿ ﭗ ﺮﻏﻻ و موﺎﻘﻣ ﻪﺑ ﻗﺎﭼ ﯽ ﻣ ﯽ دﻮﺷ .ا ﯾ ﻦ تاﺪﻫﺎﺸﻣ نﺎﺸﻧ

ﻣ ﯽ ﺪﻫد ﻪﮐ ﺘﭙﻟ ﯿ ﻦ ﻊﻧﺎﻣ از اﺰﻓا ﯾ ﺶ نزو ﻣ ﯽ دﻮﺷ و اﺰﻓا ﯾ ﺶ ﺳﺎﺴﺣ ﯿ ﺖ ﺘﭙﻟ ﯿ ﻦ رد ﻪﻠﺑﺎﻘﻣ ﺎﺑ ﻗﺎﭼ ﯽ ﺮﺛﺆﻣ ﺖﺳا ) 39 (.

ازا ﯾ ﻦ ور ﻦﯿﺘﭙﻟ ﺶﻫﺎﮐ ﻪﺑ

لﺎﺒﻧد

ﺖﺳا ﻦﮑﻤﻣ ﯽﺷزرو تﻼﺧاﺪﻣ رﺎﮐوزﺎﺳ

ﯽﺧﺮﺑ ﻦﯿﻨﭽﻤﻫ .ﺪﺷﺎﺑ ﯽﺷزرو تﺎﻨﯾﺮﻤﺗ ﺪﯿﻔﻣ رﺎﺛآ ياﺮﺑ ﯽﻟﺎﻤﺘﺣا تﺎﻘﯿﻘﺤﺗ

نﺎﺸﻧ داد ه ﺪﻧا ،ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ

ار ﻦﯿﺘﭙﻟ حﻮﻄﺳ ﻪﻧ

ﻂﻘﻓ ﻪﺑ ﺶﻫﺎﮐ ﺐﺒﺳ ةدﻮﺗ

ﺶﻫﺎﮐ ،ﻦﯿﺘﭙﻟ ﺖﯿﺳﺎﺴﺣ ﺶﯾاﺰﻓا ﻖﯾﺮﻃ زا ﻦﯿﻨﭽﻤﻫ ﻪﮑﻠﺑ ،ﯽﺑﺮﭼ ﻣ

ﯽ ﺪﻫد ) 40 (.

،ﺮﮕﯾد فﺮﻃ زا يﻮﻘﻠﺣ تﺎﻔﺴﻓﻮﻨﻣ ﻦﯾزﻮﻧدآ

ﺪﺒﮐ و ﯽﺑﺮﭼ ﺖﻓﺎﺑ رد1

ﻪﺑ ﺳو ﯿﻠ ﮥ زﻼﮑﯿﺳ تﻼﯿﻧدآ ﻢﯾﺰﻧآ 1

ﻮﺗ ﺪﯿﻟ ﻣ ﯽ دﻮﺷ ﻢﯾﺰﻧآ ﻦﯾا .

يور و هدﺮﮐ ﻞﻤﻋATP

ﻮﺗ ار تﺎﻔﺴﻓوﺮﯿﭘcAMP