受賞者講演要旨 《農芸化学奨励賞》 - 日本農芸化学会

X

! !"#$%%&'( )

*+ X,)-. !#/+#0 '( 1"20 #$3%!'4 56# &+'7 8()#9 )!'1+6 : ; #<=>?@

*A-#0B'(+6,C-D EFGHIJKL M : ; #% X, )2' )!'1+.N O( +/P6 ,C-D%Q0!'(

1. !"

,CA12 RS: ; #3465S$

TUVWXYZ[\ 6]78&#92^9&:_9

`+._9;<=a > bc&#9R?9&

:_9` _9` @dAeOfghZ78 i\jH&

BCkDE2'i\jH& =a#9F/#GlH 0'( 1,C-DIJ!',C-D (sulfotransferase)+mno'( ,C-D&

KC/Jp\³῍-YTYJqrf\^-5῍-YTY sZtuKv^(PAPS),C-D!'IJ!'(

,C-D .wx9A1&y+zZ{L,7y M6B'( A1&y,C-DN&+

+$ zZ{L,7y,C-D @d|i\jH&

&++'( OP1o 6,C-DS A1&y+}~TQ65,C-D³R S zZ{L,7y+€vzZ{26j‚\,C 7TƒU65,C-D²RS,„…&',C- D+†‡o'i\jH&²RS3%B O( 1o)Aˆ0O,C-D<=>?

@%V‰!'(

2. #$%&'()*)+,-.)/0+1.)23145 (EST)^X

ESTWX^33,000ŠY9i\jH&6 €v6Z

Q6 }~T6Z[\6]‹'( JHŒiK

&^9YZ[\6&'ŽTvV\³turKZ ,C-D!'IJ R_`O&/

&+!'( -D2$&ŽTvV\_9a

‘ ŠY9-b-'(

,C-D+’c) EST, JHŒ

iK&6&'^b-ŽTv‚{“KZ^(E2) PAPS kT^PAP3'7+ˆ0O( .,” EST ^a/b+0S$ E2 PAP+/i\jH&

M+"9d‡o'()6,7O( &,7+e ,7%#-0Ov\•Z#0S$ &+e -.o–oRi\jH&2f0B —_

96 ORg+˜1+-hi6B'( jklK!#^E2m ESTnlK9Jp rC-^E2od0'+p™E2qr³

turKZ+¹⁷KC EST^Lys106+ His108, Asn86-.o–oK,7O( O-0 ESTlK9sš›t+K,7qu20 &

vw#x+uœ3'+žŸo'( PAP5῍+³῍y%E\C+8K,7+Jq>

\E\g+8Ti ¡\g,7 ¢Phe229+^Trp53£ 2 0z¤:oO(3῍E\CPAP, PAPS{¥!|

x'OEST-^{PAP, PAPS}}~!'&

O0 1K,7-F/6&'+žŸo'(

3. 67&8+9:1. ^N-;<=>145^/N-)/

0+1.)23145¹ !"?@A.^(NST1) X

j‚\,C^N-qJŒ¦‚KL^/N-TZYv‚\Ttu‚K L^(NDST-1) j‚\,C7TƒUS N-JŒ

¦ZgZ§sp\JŒ¦ZJpr¨x© :, C-D!'IJ!'6&'( OP €v NDST-1TZYv‚\Ttu‚KLX<W\^(NST1) …6]‹:ª TZYv‚\Ttu‚KL_9«&'i\

jH&€O( 1i\jH&^PAP+'7()6,

`ˆ Se-MettO^MAD"6s€

3%O( NST1/^a/b6&0O( 4. B!"@CDEF

NST1, EST+jk2¬O^PAPS,7

­O/6&0O(O-0F®7‡ª20 PAPSm!'sm!#x¯°‚±!'1+-6B EST 6ƒh:o'_9² NST1b6m5'1 +6 NST1_9²ƒh!'1+-6BO( { ,C -D„D()³¬!#+žŸo'^ESTῌ

PAPῌvanadata'7+F®7‡ª20

ESTS_9²6&'+žŸo'Lys48, Lys106, His 108.o–om NST 1Lys 614, Lys 676, Glu642-…xO(

NST1^Lys614 EST^Lys48+M+"9pe

pe§\Y<Kf´\6|xS$ p†Gl ¢PAPS ,C+⁵῍E\C+8µE {C¨Vv\

¶‡£ '1+-·¸:o'( NST1^Lys676 EST^Lys106+M¹p†#x&$ ,C„D() Sº%`'+žŸo'( NST1^Glu642 ,C--D:o'+žŸo'x+K,76B'… x'( GluVv\ˆ‰+5B˜'JprC 6&'1++ EST^His108+p†&m!'V v\ˆ‰+Gl'+žŸo'(

G

ˆŠP»¼/P ½`‹ŒŠ 21

^{NST1 EST}

!"#$%

"&'()*+, -*"#./

01 2 .3$45678'&'(

9:;<#=

> .3?@AB CDEFD!G H ABI*#< ABJK .3?@

LMNONPQRS(TUVWX!G P YOZPZ[)\S(]^AB_)`abc

&'(= d1 efg .3?@)h'&AB*

ij&kl mno\pj& qrCD!s ABij&'(=

AB tu`D`DvDABv NIEHS/NIH (USA),

kwx`y`D`DvDABv)k'&z+<#*{|

l AB}~&€;l ‚ƒ„ ƒ '

#€a…#tu`D`DvDABv!† ‡ˆ‰

NIEHSŠ‹Œ"C `y`D`DvDABv#Ž

ˆ‰)‘wlm’'#…S= AB AB“

HDC P”MAB•–$)w(*{|l )

—˜%™š…S= …# DC›œwlABƒ„'#

€'#&'`D()ˆ‰žŸ*+,C)m’'#…S= NIEHS)k'&CD ¡¢£)h'&ƒ„'#€'

#-¤¥./¦ qr§¨)h'&ƒ„'#€'#^Lars Pedersen/¦)m’'#…S=k+l) ©0ª)ƒ«¬

€;'…#­®D~¯1°23]±²³C!x )ƒ°´µl…#¶C)—˜%™š…S=

ῌ ²² · ­®D©0ª ¸ ¹ªº»¼4½