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C. Remesy, and A. Scalbert, BioFactors, 22, 241῎243 (2004).

2) H. Ito, M.P. Gonthier, C. Manach, C. Morand, L. Mennen, C. Remesy, and A. Scalbert, Br. J. Nutr., 94, in press (2005).

3) L. Y. Rios, M. P. Gonthier,, C. Remesy, I. Mila, C. Lapi- erre, S. A. Lazarus, G. Williamson, and A. Scalbert,Am.

J. Clin. Nutr.,77, 912῎918 (2003).

4) >? @ABC 0 D EF? G HI 56782005 !8 JK"L 5) L. Y. Foo, Y. Lu, A. B. Howell, and N. Vorsa,J. Nat. Prod.,

63, 1225῎1228 (2000).

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1) K. Kimura and T. D. H. Bugg:Nat. Prod. Rep.(Review), 20, 252῎273 (2003).

2) S. Kagami, Y. Esumi, M. Nakakoshi, M. Yoshihama and K. Kimura:J. Antibiot.,56, 552῎556 (2003).

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1) Mari Yotsu-Yamashita, Robert L. Haddock, and Take- shi Yasumoto,J. Am. Chem. Soc.,1993, 115, 1147῍1148.

2) Mari Yotsu-Yamashita, Takeshi Yasumoto, Shunichi Yamada, Fe Farida A. Bajarias, Mirriam A. Formelozsa, Marc Lawrence Romero, and Yasuo Fukuyo,Chem. Res.

Toxicol.,2004, 17, 1265῍1271.

3) Mari Yotsu-Yamashita, Tetsuya Seki, Valerile J. Paul, Hideo Naoki, and Takeshi Yasumoto,Tetrahedron Lett., 1995, 36, 5563῍5566.

°¦ Fe F. A. Bajaria, Mirriam A. Formelosza ±²

³ ´46µ¶·¸H9¹º»¼{ p. 671῍676 (2004).

5) Louis Barriault, Serge L. Boulet, Kenshu Fujiwara, Akio Murai, Leo A. Paquette and Mari Yotsu-Yamashita, Bioorg. & Med. Chem. Lett.,1999, 9, 2069῍2072.

Fig. 1 The structures of polycavernoside congeners and their ESI-MS/MS fragmentation patterns (aῌd)