WORKSHOP:
An Introduction
to Mathematical Modeling for Systems Biology
18-19 February 2009
Presented by
DR. ROELAND MERKS
Netherlands Institute for Systems Biology The Netherlands
Tentative Schedule
Day 1
8:30 a.m. – 9:00 a.m.
Registration of Participants 9:00 a.m. – 9:30 a.m.
Welcome Address 9:30 a.m. – 10:30 a.m.
Introduction to Systems Biology and Mathematical Modeling
10:30 a.m. – 11:00 a.m.
Coffee Break
11:00 a.m. – 12:30 p.m.
Dynamics of Single-Cell Behavior 12:30 p.m. – 2:00 p.m.
Lunch break
2:00 p.m. – 4:30 p.m.
Hands-on session: Cell-based Modeling 4:30 p.m. – 5:00 p.m.
Tea Break
Day 2
9:00 a.m. – 10:30 a.m.
Cell-Based Models of Multicellular Phenomena - Animal Development
10:30 a.m. – 11:00 a.m.
Coffee Break
11:00 a.m. – 12:30 p.m.
Cell-Based Models of Multicellular Phenomena - Plant Development
12:30 p.m. – 2:00 p.m.
Lunch Break
2:00 p.m. – 4:30 p.m.
Hands-On Session: Cell-based Modeling 4:30 p.m. – 5:00 p.m.
Conclusion, Q&A and wrap-up Tea Break
Institute of Systems Biology (INBIOSIS)
Universiti Kebangsaan Malaysia Bangi
Institute of Systems Biology
(INBIOSIS)
Name:
Institution:
Address:
Tel: Fax:
Email:
Signature:
Attendance confirmation should be made before 16 February 2009 and sent to Institute of Systems Biology (INBIOSIS),
Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor Darul Ehsan or
faxed to 03-89213398
Workshop fees: RM 100.00
Registration fee covers workshop materials, tea and lunch must be paid in full prior to or on the day of registration.
Method of Payment:
Check Money Order Postal Order
All payment made payable to “Bendahari Universiti Kebangsaan Malaysia”
Abstract
DR ROELAND MERKS
Netherlands Institute for Systems Biology (CWI The Dutch National Center for Mathematics
and Computer Science) Amsterdam, The Netherlands
Experiences
2008-Present : Project Leader ‘Biomodeling and Biosystems Analysis’
2007-2008 : Young Leader, Flanders Institute for Biotechnology (VIB) and Ghent University,
Belgium
2005-2007 : Postdoctoral fellow, VIB/Ghent University (Marie Curie Intra-European fellowship)
Department of Plant Systems Biology 2003-2004 : Postdoctoral researcher, Indiana University Bloomington, Biocomplexity Institute and Department of Physics, Indiana University,
Bloomington, USA Research Areas Theoretical Biology
Systems Biology Computational Biology
Enquiries:
Nur Hasrina Mohar Tel: 03-89214558 / 4549
Email: [email protected] / [email protected]
Plant organs, including leaves and roots, develop by means of a complicated, multi-level cross-talk between gene regulation, patterned cell division and cell expansion, and tissue mechanics. In contrast to the cells in many animal tissues, plant cells cannot migrate and, with very few exceptions, they cannot slide past each other. Consequently, plant morphogenesis depends entirely on patterned cell division, cell expansion, and cell differentiation. Thus plant development requires different cell-centered models than those developed for animal development, in which cell migration and tissue folding play a primary role.
We will present a cell-centered computer-modeling framework for plant tissue morphogenesis, and show its application to the development of a Virtual Leaf model. Eventually, the Virtual Leaf should provide insight into gene function in the context of a growing leaf. Thus it should help plant researchers understand how the genetic knock-out or overexpression of a developmental gene will alter the normal course of development.
We will illustrate the current use of the Virtual Leaf model with examples of auxin-driven vasculature development, determination of leaf shape, and meristem growth.
Guest Speaker Registration
Details Date : 18-19 February 2009
Venue : Centre for Gene Analysis and Technology Institute of Systems Biology (INBIOSIS) UKM, Bangi
