CHAPTER I INTRODUCTION
C. Recommendations
1. In view of the data generated on rat serology and histopathology in mice exposed to T. gondii suggestive of the existence of avirulent/low virulent and virulent parasite strains in R.
norvegicus and R. rattus mindanensis, the isolation and gene analysis of parasite DNA is worth undertaking.
2. In vitro cultivation as well as, in vivo maintenance of T.
gondii parasites in mice isolated from R. norvegicus and R.
rattus mindanensis is worth doing to provide a ready source of parasites for use in experimental and immunologic studies.
3. To extend the serologic survey to other species of rodents, and R. norvegicus and R. rattus mindanensis from other collection sites.
4. Histopathologic evaluation should be extended to organs not covered in the present study, such as the kidneys, intestine and lymph nodes.
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A P P E N D I C E S
APPENDIX A
Life cycle of Toxoplasma gondii
APPENDIX B
Serologic assay for the presence/absence of anti- T. gondii antibodies (Abs) in field-collected rats