Organic Chemistry 1 (คม251)

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คณะวิทยาศาสตร์ มหาวิทยาลัยแม่โจ้

Organic Chemistry 1 ( คม 251)

อาจารย์ ดร.วชิระ ชุ่มมงคล

Referents

Organic Chemistry, 8^th (2012) and 7^th (2008) Edition John McMurry.

http://www.4shared.com/office/VbLzueBV/McMurry_Organic_Chemistry_8th_.htm Organic Chemistry, 4^th (2000) Edition

Francis A. Carey.

http://www.4shared.com/office/ca4aCoED/ORGANIC_CHEMISTRY_4th_ed_-_Fra.htm Organic Chemistry, 7^th (2010) Pearson International Edition

Leroy G. Wade, JR.

http://www.demonoid.ph/files/details/2658511/002130706434/

Atomic structure, hybridization, chemical bonding, stereochemistry, classification, nomenclature, synthesis, reaction mechanisms, physical and chemical properties of

1) Alcohols and Phenols (7 %) 2) Ethers and Epoxides (7 %) 3) Aldehydes and Ketones (7 %)

4) Carboxylic acids and their derivatives (7 %)

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Overview of Organic Reaction

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Nucleophile (Nu

^-

)

Electrophile (E

⁺

) Acids (H

⁺

donors) Bases (H

⁺

acceptors)

Leaving Group (L)

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Alcohols and Phenols

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1 Steric effect

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2 Electronic effect

- Inductive effect

- Resonance effect

Phenol

p-Nitrophenol

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Hydration of alkenes

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1) BH

₃

/THF 2) NaOH/H

₂

O

₂

1) Hg(Oac)

₂

/H

₂

O 2) NaBH

₄

1) OsO

₄

/pyridine 2) NaHSO

₃

/H

₂

O

1) mCPBA/DCM

2) H

₃

O

⁺

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Reduction of carbonyl Groups by Hydride Donors

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Ester reaction

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Dess-Martin periodinane

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