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Literature survey for Federated Learning in Medical COVID-19 Applications 55

CHAPTER 2: LITERATURE REVIEW

2.4 What are the current distribution challenges for the SARS-CoV-2 treatment taken the

2.5.2 Federated Learning for Medical COVID-19 Applications

2.5.2.1 Literature survey for Federated Learning in Medical COVID-19 Applications 55

FL is a wide concept bringing the code to data rather than the data to the code and offers solutions to basic issues associated to data discretion, localisation and ownership. Federated fundamentals with ML have attracted considerable interest and have been used in many fields, especially in the medical sector. The frequency of their use has considerably increased after the outbreak of the SARS-COV-2 pandemic. Thus, patient data sharing and privacy have become main concerns.

Table 2.3 lists the eight studies that explored the use of FL for COVID-19 applications.

Table 2. 3 Literature Survey for Federated Learning in Medical COVID-19 Applications Author & Year Contribution Case Study Federated

Fundamental

Yang, Xu et al. (2020)

This study proposed a novel federated semi-supervised learning

technique (with or without

annotations) for effectively utilising available data in addressing

variability in both data and annotations.

Chest computed tomography

Federated and semi- supervised learning as traditional ML

Akhil Vaid and Suraj K Jaladanki et al.

(2021)

This study aimed to use federated learning technique to prevent local accumulation of raw clinical information across several institutions and forecast death in hospitalised COVID-19-positive

Electronic Health Records

Least absolute shrinkage and selection operator federated

Multilayer

perceptron federated as traditional ML

patients within 7 days.

Liwei Ouyang, Yong Yuan and Yumeng Cao et al. (2021)

The authors

proposed a

collaborative early warning style associated to blockchain and smart contracts for COVID-19, and the

goal was

crowdsourcing early warning

errands to

distributed stations in medical

institutions, people and other social strata.

Early warning for COVID-19 based on blockchain and smart contracts

The strategy combines the monitoring results of two screening methods, medical federation screening based on federated learning and social association screening based on the learning markets method to alert new cases as traditional ML

Wang, Xu, Ma, Talha, Al-Rakhami and Ghoneim et al. (2021)

This study proposed a 5G-enabled auxiliary diagnosis architecture based on federated learning for many institutions and central cloud cooperation to enable the sharing

of high

generalisation performance diagnosis models

5G-enabled federated learning auxiliary diagnosis of COVID-19

COVID-19 severity classification

Experiments were run on a central cloud and three edge cloud servers to ensure that the suggested architecture and model cognition technique were effective similar to traditional ML

Kumar, Khan, Zhang, Yang, Golilarz, Zakria, Ali, Shafiq

This study proposed a framework that collects a limited quantity of data from various sources (different hospitals) and uses

COVID-19 detection using CT imaging

Deep learning

and Wang et al.

(2020)

blockchain-based federated learning to train a global deep learning model

(Pang, Huang, Xie, Li and Cai et al. (2021)

This study proposed a framework that combines digital twins (DTs) of cities with federated learning to provide a

novel collaborative paradigm that enables numerous city DTs to share local

strategies and status quickly

City DTs to share local strategies and status quickly

Federated learning central server manages local updates from multiple

collaborators (city DTs), generating a worldwide

framework focused

on manifold

iterations at various city DT policies until the framework learns associations among different response stratagems and contamination trends, such as traditional ML (Zhang, Zhou, Lu,

Wang, Zhu, Sun, Wang, Lo, Wang, et la., 2021)

This study proposes a novel federated learning

approach based on dynamic fusion for medical diagnostic imagery analysis to diagnose

Coronavirus comorbidities.

COVID-19 Detection using Dynamic Fusion- based Federated Learning

DYNAMIC FUSION-BASED FEDERATED

LEARNING as

traditional ML

Feki, Ammar,

Kessentini, and Muhammad et al.

(2021)

This study proposed a federated learning system that allows several medical organisations to

apply deep

knowledge to scrutinise the virus from chest X-ray

Screening COVID-19 from chest X-ray images

Federated learning of a deep CNN model

imagery while maintaining

confidentiality.

As shown in Table 2.3, eight articles focused on the use of FL in medical applications, such as COVID-19 detection using CT imaging, early warning for coronavirus based on blockchain and shrewd comparison and local strategy and status share of city DTs. Federated fundamentals well suited and widely used with ML models. Six of eight studies contributed to traditional ML, and the remaining studies contributed to deep learning that overcome the first obstacle of privacy (data sharing issue). However, no research explored prioritisation challenges. In other words, the second challenge cannot be addressed, which requires a precise decision-making approach to resolve the three prioritisation issues outlined. This situation is considered a research gap.

2.5.3 Point of view for Multicriteria decision making & Treatment Distribution

Apart from analysis, MCDM is regarded as a solution that assists experts in organising and solving any prioritisation issue (M. A. Alsalem et al., 2021). MCDM is defined as a decision theory extension covering any decision with multiple objectives and is a technique for evaluating options according to several contradictory criteria and for merging them into a single inclusive evaluation (M. A. Alsalem et al., 2021). Therefore, MCDM provides great benefits as a decision science support technique and has been used in the context of SARS-COV-2 along with a variety of applications. Identifying the prioritisation issue (second challenge) of SARS-COV-2 treatment recipients as an MCDM issue has been discussed in the literature. T. J. Mohammed et al. (2021) proposed an intelligent framework based on the MCDM context and successfully addressed patients’ prioritisation issue in distribution hospital networks and issues in the transfusion of

efficient CP from donors to the most critical SARS-COV-2 patients as an early treatment (i.e. pre- vaccination stage). However, this framework relied on sharing donors’ and patients’ data in all hospitals (distribution hospitals) and combined them in a decision matrix for donors and in another decision matrix for SARS-COV-2 patients for prioritisation and matching. The privacy and sensitivity of patients’ and donors’ openly used data were ignored.

To date, no study has integrated the federated fundamental with MCDM techniques for SARS- COV-2 treatment. To bridge this gap, integration is essential to characterise the supply of anti- SARS-CoV-2 mAbs in distribution hospitals. Therefore, the formulation of a new federated fundamental concept called ‘Federated-Decision Making Distributor (FDMD)’ is necessary to overcoming challenges towards ensuring the privacy of health SARS-COV-2 data and prioritising anti-SARS-CoV-2 mAb recipients in distribution hospitals.