In vitro evaluation of parasitostatic activity of Asafoetida oleoresin on bloodstream Trypanosoma brucei brucei. In vitro evaluation of the parasitostatic activity of asafoetida oleoresin on bloodstream Trypanosoma brucei brucei. Determination of the half-maximum effective concentration (EC50) using the Alamar Blue survival assay: the metabolic function of the cells is shown using Alamar Blue (Resazurin NaCl dye).
Determination of treatment efficacy in mitochondrial membrane potential by flow cytometry: Tetramethyl-rhodamine ethyl ester (TMRE) staining determines changes in mitochondrial membrane potential as an indicator of metabolic toxicity of freshly harvested protozoa as previously described (31-33 ). The cell growth curve showed exposure time- and concentration-dependent inhibition after recovery. Cell cycle analysis used DNA propidium iodide fluorescence of fixed cells to measure cellular DNA content fluorescytometrically after treatment.
The results of this study showed promising trypanostatic activity of the natural plant oleoresin asafoetida. A high EC50 may indicate the necessity of studying the effect of the purified active ingredients of the extract.
Original Article
Adhesive Capsulitis and Its Predictors in Saudi Diabetic Patients
It is also clear that the non-dominant shoulder in patients is somewhat more likely to be affected by AC and commonly affects the contralateral side years after the onset of symptoms in the first shoulder(1,4,5). This group will be more likely to develop diabetic complications, including AC, which is one of the least easily recognized complications of DM. The study consecutively included all DM patients (type 1 and 2) who sought treatment at the center's Diabetic Outpatient Clinic (OPD).
The Arabic version of the SPADI questionnaire used was previously validated in Saudi Arabia by Alsanawi(13). Although we account for the full range of motion of the shoulder, we focus on limited external rotation of the shoulder because there are few conditions that cause this limitation that is (glenohumeral arthritis, locked shoulder dislocation, separated head fracture) and can be excluded from the simple shoulder. radiography. Regarding the type of treatment, we found that 33.3% of patients receiving insulin and oral hypoglycemic drugs (OHD) for glycemia.
Out of the 411 patients with diabetes who were interviewed, 7.5% had AC, confirming our hypothesis that the prevalence of AC in DM patients will be in a higher range compared to international reference. Furthermore, most of the investigated cases in this study were found to be unilateral. Therefore, the independent measurement of the level of disability in diabetic patients with AC is quite important.
Programs promoting AC awareness are strongly encouraged to be organized for diabetic patients periodically, especially if they are women, to provide them with information about its increasing prevalence among this segment of the population, its risk factors, as well as clinical presentation of AC. Nevertheless, this study was the first study in Saudi Arabia to evaluate the prevalence of AC in the northern part of the kingdom. Cross-cultural adaptation and psychometric properties of an Arabic version of the shoulder pain and disability index.
Effectiveness of a New Approach to Student-Led Seminars in a Saudi Medical College: Student Perceptions.
Effectiveness of the New Approach of Student-led Seminars in a Saudi Medical College: Students’ Perceptions
The subject is part of the content of a specific course, which is not covered by other educational activities. The process included explanations of the changes to students and faculty with an emphasis on using the rubrics in the preparation and evaluation of presentations. However, almost a third of Group B students felt that the former approach was better in helping them improve their research skills and.
In this study, students believed that the new approach increased the educational benefits of SLS; specification of objectives reduced their workload and helped them better focus their research and preparation. In addition, half of the students felt that presenting information already covered in other teaching methods was very helpful for learning concepts. Regarding the supervisory approach, 57.0% of respondents agreed that feedback through counseling was helpful in better focusing on specific skills.
Nearly one third of the students (34.0%) from group B stated that the previous approach helped them better to improve their search skills. This study was funded by Qassim University, Saudi Arabia; as part of the authors' work duties. Women with epilepsy are more likely to experience menstrual disorders related to infertility, with one-third of women with epilepsy experiencing them compared to one-seventh of women in the general population (1,2).
Of the 60 patients, there were idiopathic generalized epilepsy (GE) and symptomatic localization-related focal epilepsy (LRFE). All 15 control subjects had regular menstrual cycles, normal basal cycle hormone levels, and normal ovarian pelvic ultrasound results. Of the 60 patients with epilepsy, 38 had regular menstrual cycles and normal basal cycle hormone levels and normal pelvic ovarian ultrasound findings.
In our study, we found significantly lower estradiol and DHEA-S levels in the 25 treated patients without reproductive hormone disorders compared to the healthy controls in the early phase of the basal cycle. Abdelmgeed and Ali were involved in the conceptualization and design of the study and writing of the manuscript. A study of the polycystic ovary syndrome on the Greek island of Lesvos: hormonal and metabolic profile.
Case Report
Adult Attention Deficit Hyperactivity Disorder: A Case Report
He was given oral sodium valproate 1000 mg once daily (OD) and quetiapine 300 mg PO at bedtime and still showed little sign of improvement. In the second meeting with the patient and his wife, more details about his childhood were gathered, and he had a positive history of attention problems, hyperactivity, and impulsivity. This pattern started in childhood, although the patient showed some improvement while taking medication, becoming less impulsive and hyperactive.
In general, he was disorganized, unable to manage tasks or keep things in order, and also lost things easily. The patient was always restless, unable to sit still and unable to perform any activity quietly. The patient was carefully screened positive for ADHD using the Adult ADHD Self-Report Scale (ASRS-v1.1) Symptom Checklist.
Regarding his symptoms, the patient was diagnosed as adult ADHD with a comorbid presentation, according to DSM 5, with a high score on ASRS-v1.1. Not meeting BPD criteria, he was started on Concerta 18 mg (methylphenidate) and showed great improvement in hyperactivity and attention, but he also complained of liptics, which resulted in discontinuation (DC) before lowering the sodium valproate dose. We started atomoxetine up to 80 mg PO once daily and the patient showed more improvement.
Since then, the patient has started to taper the dose of sodium valproate down to DC. However, the family began to complain that he was easily irritated and hot-tempered. It is unlikely that the patient has BPD because he has never had manic or depressive episodes, or hypomanic symptoms, and was not episodic in nature and did not improve with mood stabilizers.
The patient met criteria for ADHD because he had persistent symptoms of inattention that were inconsistent with his developmental level; it had direct negative effects on his social and academic/professional functioning; he can't pay attention to specifics or done.
AUMJ Comprehensive Instructions For Authors and Reviewers
Simultaneous scientific implication of the case ('suspected minor plagiarism'), also judged by reviewers and editors. All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content , (3) final approval of the version to be submitted. List all affiliations with a superscript Arabic number immediately after the author's name and before the appropriate address.
For parametric data, variance should be reported as 95% confidence limits or standard deviations rather than as standard error of the mean. The statistical analysis used should be appropriate for the objectives of the study and the type of data analyzed. This should explore the significance, interpretation and reasoning of work results vs.
Acknowledgments and Funding Collect the acknowledgments in a separate section at the end of the article before the references. The aim of the mini-review is to provide a concise and highly up-to-date summary. High-quality manuscripts are peer-reviewed by at least two experts in the same field together with a biostatistician if the study requires it.
A one-month review process cycle is the goal of the journal from submission to final acceptance. Continued open peer review after publication is highly recommended by submitting comments to the editor on any published article that will appear with the author's reply in the next issue of the journal. The Editor-in-Chief of the journal will have sole authority to make the final decision on acceptance or rejection in any dispute.
Please score the manuscript from 0 to 4 (highest) for each of the following items and sum up the total score. The corresponding author will be provided, at no cost, a PDF file of the article via email (the PDF file is a watered down version of the published article and includes a cover sheet with the image of the journal cover and a disclaimer outlining the terms and conditions of use). I understand that material to be published in the Aljouf University Medical Journal will be included in any reprint of the published article.
Manuscript Submission and Copyright Transfer Form
