Objectives: We present a review of articles published on intravitreal steroid implants in the treatment of diabetic macular edema to examine the rationale, advantages, and disadvantages of using these implants. Cost-effectiveness of ranibizumab versus aflibercept in the treatment of visual impairment due to diabetic macular oedema: a UK healthcare perspective. Efficacy and safety results of 0.19 mg fluocinolone acetonide implant after pretreatment with 0.7 mg dexamethasone implant in patients with diabetic macular edema.
Clinical Review Report: Dexamethasone (Ozurdex): (Allergan Inc.): Indication: For the treatment of adult patients with diabetic macular edema who have pseudophakia. Combined phacoemulsification and intravitreal dexamethasone (Ozurdex®) implant in diabetic patients with concomitant cataract and diabetic macular edema. Combined intravitreal dexamethasone implant and micropulse yellow laser for the treatment of anti-vegf resistant diabetic macular edema.
A meta-analysis of the effect of an intravitreal dexamethasone implant versus intravitreal anti-vascular endothelial growth factor treatment for diabetic macular edema. Ozurdex® intravitreal dexamethasone implant in naïve and refractory patients with different subtypes of diabetic macular edema. Health-related quality of life, visual function, and treatment satisfaction after intravitreal dexamethasone implant for diabetic macular edema.
Original Article
Conformal CT Planning vs. Conventional Planning for Supra- Clavicular Lymph Nodes Irradiation in Egyptian Patients with
Globally, breast cancer is the most common cancer and the leading cause of cancer death in women; it accounts for 23% of all cancer cases and 14%. Changes in practice have been documented in surveys conducted by the National Breast Cancer Center Radiation Oncology Expert Advisory Group regarding SCF field size, treatment parameters, and depth (6). The protocol of this study was approved by the Bioethics and Scientific Ethics Committee of Zagazig University Faculty of Medicine.
For breast cancer adjuvant radiotherapy we used two conventional plans; 6MV photons prescribed to 1.5 cm (Dmax, 6MV-1.5) or to 3 cm depth (6MV-3.0) together with a 3rd plan that combined 6MV and 15MV photons manually optimized to cover the target volume with 90 % of the prescribed dose for comparison. These results are consistent with Liengsawangwong et al's study, where the conformal plan was the most successful for all BMI groups, while the conventional 6MV-3.0 generated the most frequent hotspots and reached an average of 105% of the prescribed dose(10). Houshyari et al study stated that although the coverage of the 2½D 6MV-3.0 plan was accepted in all BMI classes, it had hotspots that reached 120% of the prescribed dose.
There were no changes from baseline in 45.1% of patients, and none of the patients suffered from a grade 4 skin reaction. The 3D conformal radiotherapy planning for SC LNs provides better coverage of the target and offers more dose homogeneity than the conventional 2½D planning to 1.5 cm or 3 cm depth from the skin surface across different BMI classes. This study was funded by Zagazig University, Zagazig, Egypt as part of the authors' employment obligation.
Impact of postmastectomy radiation on loco-regional recurrence in breast cancer patients with 1-3 positive lymph nodes treated with modern systemic therapy. Treatment optimization using computed tomography-delineated targets should be used for supraclavicular irradiation of breast cancer. Optimizing the tangential technique and supraclavicular fields in 3-dimensional conformal radiotherapy for breast cancer.
CT-based three-dimensional assessment of supra-clavicular and infra-clavicular joints and calculation of administered dose. Radiation pneumonitis in breast cancer patients who received radiotherapy using the partially wide tangent technique after breast conserving surgery.
Unmet Needs of Depression among University Students: A Northern Saudi Cross-Sectional Study
Therefore, this study was designed to assess the prevalence of depression among students at Jouf University and to determine the unmet needs of depression and its predictors among the study population. To the best of our knowledge, there is no research available in Saudi Arabia that has assessed unmet needs for depression among college students. A Chi-Square test was performed to identify risk factors for depression and logistic regression analysis was performed to identify risk factors of unmet needs.
Of the 400-sample studied participants were diagnosed as having some form of depression as checked by the PHQ-9 questionnaire. Further analysis was done among 85 people who were depressed to look for unmet and fulfilled depression needs. In the current study, 36 students (42.4%) of the total who suffered from any form of depression had an unmet need for depression (Table 3).
Even the theme of World Mental Health Day in 2019 was focused on suicide prevention, which is one of the biggest consequences of depression(33). This can be achieved not only by assessing the extent of depression, but also by assessing unmet needs for depression. In contrast to our current study, a study conducted in Malaysia by Nahas et al(35) in 2019 found that 36.4% of public university students suffered from some form of depression.
Age group < 20 years, students who did not have health care, hosts and daily smokers had significantly higher unmet needs for depression. Therefore, we recommend screening for depression among all university students at the entry level and subsequent screening each year to detect depression and its unmet needs. Prevalence and associated factors of depression among the general population in Al-Ahsa, Kingdom of Saudi Arabia: a community-based survey.
Prevalence and associated factors of depression in patients with diabetes in Saudi Arabia's Jazan province: a cross-sectional study. Prevalence of depression and its association with socio-demographic factors in patients with chronic pain: a cross-sectional study in a tertiary care hospital in Saudi Arabia.
The use of an Electronic Augmentative Communication Device to assess the needs of Mechanically Ventilated
Thus, ICU nurses appear to require comprehensive training and educational support to maintain effective and efficient communication with IMV patients. Thus, the main purpose of this study was to determine the needs of IMV patients during the use of an electronic AAC device during the IMV period. The collected data can be considered a basic study in the field of communication with IMV patients.
Descriptive design was used due to its benefit in obtaining empirical information addressing the most common needs of IMV patients when using electronic AAC. Prior to the introduction of AAC devices to patients, training was conducted for nurses on the importance of communicating with IMV patients and how to operate the electronic AAC device. The needs of IMV patients integrated into that application included basic physiological needs such as eating, drinking and toileting.
Findings from the current study showed that the third most reported needs of IMV patients were to change position (37%), change the height of the head of the bed (31%), and suction (35%). It is well documented in the literature that patients with IMV feel suffocated and most patients with IMV report discomfort from oral secretions (16,17,19). The patients with IMV who reported dyspnea in this study are in agreement with the findings of Karlsson et al., that patients with IMV consistently reported difficulty breathing.
For this reason, 31% of the IMV patients in the current study asked to listen to the Qur'an. In view of this, an accurate assessment of the spiritual needs of IMV patients could improve effective spiritual care(22). The findings of this study demonstrated the effectiveness of using the "Be My Voice" application installed on an AAC device to facilitate communication between ICU nurses and IMV patients.
Improving communication with IMV patients can lead to appropriate management of problems and fulfillment of patient needs. In addition, the low response rate as some IMV patients could not use electronic AAC devices due to computer illiteracy can be considered another limitation for this study.
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