Y HOC VIET NAM THANG 3 - SO 1/2012
NGHIEN CQU DAC DIEM LAM SANG U TUYEN NUlOrc BOT
T O M T A T
U tuyen nu'dc bot la mot nhom benh quan trpng trong benh hgc dau co noi chung va benh ciia tuyen nUdc bot noi rieng. U tuyen nu'dc bot chii yeu gap 6 cac tuyen nu'dc bpt chinh. Myc tieu. Nghien cii'u cac dac diem lam sang ciia u tuyen nUdc bot Doi tu'dng va phu'dng phap nghien cu'u: gdm 65 benh nhan du'dc chan doan va dteu tri tai Benh vien Tai mui hong trung iTpng tir thang 1/2007 den thang 11/2008.
Phu'dng phap nghien CLTU mo ta hdi cii'u. Ke't qua:
28 nam (41,5%) va 37 (58,5%) nQ vdi ty le nU/nam la 1,4/1, tuoi trung binh la 39,4. Thu'dng gap d nhom 21-60 tuoi (73,8%). U tuyen mang tai (63,1%), u tuyen nUdc bgt phu 24,6%. Trieu chu'ng thu'dng gap nhat la sUng phong tai vung tuyen 58,8%. Kich thu6c u hay gap nha't trong khoang 2-4cm (78,6%). Ket luan: lam sang u tuyen nUdc bot da dang, benh cd the xay ra 6 nhieu vi tri khac nhau d vung dau co.
SUMMARY
Salivary gland tumours compnse an important group of lesions in head and neck pathology.
Ojectives: study on chnical features of salivary gland tumours. Patients and methods: A retrospective study of 65 salivary glands tumours operated from 1/2007 to 11/2008 in National ENT hospital. Results:
Of these, 28 (41,5%) were male, 37 (58,5%) female (ratio of 1:1,4). The ages ranged from 9 - 7 0 with mean age of 39,4. Most of the tumours accurred at the age group of 21 - 60 (73,8%). 63,1% of tumor originated from the parotid, 24,6% from the minor salivary glands. Swell of glands were the most frequent symptom. Conclusions: Clinical aspects of salivary gland tumours varied considerably, many sites at head and neck were affected.
I.
OAT VANof
U tuyen nu'dc bpt la mdt nhdm benh quan trong trong benh hpc dau co ndi chung va benh ciia tuyen nu'dc bpt ndi rieng.
U tuyen nu'dc bot chii yeu gap d cac tuyen
Le Minh K y * , Pham Trung K i e n * *
nu'dc bpt chinh, trong dd tuyen mang tai ia khoang 70%, tuyen du'di ham la 8%, edn iai 22%
gap d tuyen du'di lu'di va cac tuyen nu'dc bpt phu.
Cd den 7 5 % u tuyen mang tai la lanh tinii, 50%
u tuyen du'di ham va 8 0 % u tuyen nu'dc bpt phy du'dc tim thay la ae tinh [ 2 ] .
Mac dii tuyen nu'dc hot nam d vi tri de phat hien tuy nhien benh nhan thu'dng den muon vi the qua trinh dieu tri trd nen khd khan. Su' phan bd khap ndi ciia cac u tuyen nu'dc bpt phu lam khd khan cho viec ehan doan. Chiing tdi tien hanh de tai vdi myc tieu: Nghien cdu cac dac diem lam sang cCia u tuyen nudc bot.
II. OOI TUONG VA PHUONG PHAP NGHIEN CCTU 2 . 1 . Ooi tu'dng nghien cii'u: 65 benh nhan u tuyen nu'dc bpt du'dc dieu tri tai Benh vien Tai mui hpng trung u'dng tu" thang 01/2007 den thang 11/2008.
a Tieu chuan chpn lua: Benh nhan ed dii chan doan du'a tren cac trieu ehimg lam sang, can lam sang, cd ket qua giai phau benh dii tieu chuan.
Khdng phan biet tudi, gidi, nghe nghiep.
2.2. Phu'dng phap nghien cu'u;
2 . 2 . 1 . Thiet ke nghien cii'u: Phu'dng phap nghien ciru md ta hdi ciru
2 . 2 . 2 . Cach thu'c tien hanh
Thu thap cac sd lieu ve dac diem lam sang;
Tudi, gidi. Thdi gian ke tir khi cd trieu chu'ng dau tien den khi vao vien (tinh theo thang), Trieu chirng xuat hien dau tien, trieu chu'ng ban dau (ly do vao vien), Cac dau hieu lam sang, vi tri va ti'nh chat u: mat dp, ranh gidi, kich thu'dc, dp di dpng, tinh trang xam lan ra md xung quanh. Cac trieu chutig di kem: Liet VII ngoai bien, dau tai u...
2 . 2 . 3 . Xir ly so lieu: Sd lieu du'dc xii ly bang phan mem SPSS 15.0.
III. KET QUA 3 . 1 . Tuoi, gfdi Bang 3.1. Tudi benh nhan
Nhom tuoi
< 20
Lanh tinh N
8 14,8
%
Ung thir N
1 9,1
%
^ BVTai MOI hong; * * Benh vien Hdu nghi Viet Xo Phan bien khoa hgc: PGS.TS. Nguyin Dinh Phuc
Y HOC VIET NAM THANG 3 - SO 1/2012
2 1 - 4 0 4 1 - 6 0
> 60 Tonq
22 19 5 54
40,7 35,2 9,3 100
2 5 3 11
18,2 45,4 27,3 , 100 Tudi mac benh trung binh la 39,4 ± 16,36, thap nhat: 9 tuoi, cao nhat 70 tuoi. Nhdm tud'i thu'dng gap nhat 21 - 60 tudi chiem 73,8%, Tuoi trung binh ciia nam la 37,7, ciia nij' la 49,7. Tudi trung binh ciia nhdm lanh tinh la 37,85±15,66, nhdm ung thu' la 47,27±18,22. Tuy nhien s\i khac biet ve tud'i giu'a hai nhdm la khdng cd si/ khac biet cd y nghTa thdng ke vdi p>0,05.
Bang 3.2. Gld'i tinh
Lanh ti'nh Ung thif Tonq
Nam N 25 2 27
38,4
%
3,1 41,5
Nif N 29 9 38
»/o 44,7 13,8 58,5
Tonq N 54 11 65
83,1
%
16,9 100 Trong 65 benh nhan cd 27 nam va 38 nti' chiem ty le tu'dng uTng la 4 1 , 5 % va 58,5%. Vdi ty le Nam/Nij' 1:1.4. NiJgap nhileu hdn nam ca d u lanh va a c t i n h . Tuy nhien su' khae biet nay khdng cd y nghTa thdng ke vdi p>0,05.
3.2 Cac dac d i e m lam sang:
3.2.1. Trieu chu'ng iuc vao vien:
Bang 3.3. Trieu ehiing luc vao vien Trieu chu'ng
U tar tuyen Dau tai tuyen Nuot vUdnq Liet mat Kho nuot Tneu chLftiq mui Khan tieng Tonq
Lanh tinh 31
4 12 0 1 5 1 54
Unq thir 4 1 3 3 0 0 0 11
Tong 35
5 15 3 1 5 1 65
Trieu chifng thu'dng gap nhat khien benh nhan phai nhap vien la su'ng phdng tai viing tuyen 58,8%. 3 tru'dng hdp cd Net mat thi deu bi ung thu'. 5/11(45,5%) benh nhan ung thu' cd tien sir bi benh tru'dc dd 6\i6c dieu tri ngoai khoa trong khi dd vdi t^ le do d u lanh chi cd 6/54 (11,1%). S\i khac biet nay cd y nghTa thdng ke vdi p<0,05.
3.2.2. Vi tri u tuyen nu'dc bgt;
Bang 3.4. Phan bo vi t r i u.
V j t r i
Tuyen mang tai Tuyen dudi ham Tuyen dUdi lUSi Tuyen nUdc bot phu Tonq
Lanh tinh N 33 6 2 13 54
80,5
%
100 100 81,2 83,1
Ung N 8 0 0 3 11
thiT
"la 19,5
0 0 18,8 16,9
Tonq N 41 6 2 16 65
100
%
100 100 100 100 U tuyen nu'dc bpt chii yeu gap d tuyen mang tai (63,1%), tuyen nu'dc bpt phu (24,6%), it gap d tuyen du'di ham (9,2%), va hiem gap d tuyen du'di lu'di (3,1%). Khdi u ac ti'nh gap 11/65 tru'dng hdp va chi gap d tuyen mang tai va tuyen nu'dc bpt phy. Trong cac khdi u d tuyen mang tai cd 80,5% la lanh tinh, 19,5 la ac ti'nh. Tuyen du'di ham, va tuyen du'di lu'di 100% lanh tinh, trong khi dd 81,2%
khdi u lanh du'dc tim thay d tuyen nu'dc bpt phu, 18,8% la ung thu'.
Y HOC VIET NAM THANG 3 - SO 1/2012
3.2.3. Kicfi thu'dc u tuyen nu'dc bgt Bang 3.5. Kich thu'dc u
<2cm 2-4cm
>4cm Tonq
TNB chinh N 2 40 7 49
4,1
%
81,6 14.3 100 3,2±l,13cm
TNB phu N 5 11 0 16
31,3
%
68,7 0 100 2,4±0,92 cm
Tonq N 7 51 7 65
10,8
%
78,4 10,8 100 3,0±1,14 cm Kich thu'dc trung binh tren lam sang ta 3,0±1,14 cm, d u tuyen nu'dc bot chinh la 3,2 cm, u tuyen nu'dc bpt phy la 2,4cm. Sy' khae biet giu'a kich thUde trung binh giu'a 2 loai nay khdng cd y nghTa thdng ke p>0,05. Kich thi/dc u hay gap nhat trong khoang 2-4cm (78,6%), u tuyen nu'dc bpt phu khdng gap tru'dng hdp nao kieh thu'dc >4cm.
3.2.4. I^oilien quan giffa dac diem u va tinh chat u.
Bang3.6. ¥IQ\ iien quan qiij'a dac diem u va tinh chat u.
Dac diem u
l^atdo
Ranh gicli Dl dong
Da, niem mac tren u
Mem Chac Cifnq Ro Khonq De Han che Khonq Binh thudng Tham nhiem
Lanh tinh N = 54
24 30 0 39 15 34 17 3 52 2
44,4
%
55,6 0 72,2 27,8 63 31,5 5,5 96,3 3,7
Ung N = 11
2 8 1 5 6 2 8 1 9 2
t h u 18,2
%
72,7 9,1 45,5 54,5 18,2 72,2 9,1 81,8 18,2 Mat dp chac chiem ty le 58,5%, mat dp
mem 40%, chi cd 1,5% mat dp ciTng. Cd 36 tru'dng hdp khdi u di ddng de va 25 tru'dng hdp di ddng han che chiem ty le tu'dng u'ng la 55,4%
va 38,4%, chi cd 6,2% la khdng di ddng. Hau het be mat da va niem mac tren khdi u la binh thu'dng (93,8%), cd 4 tru'dng hdp cd tham nhiem, ciiay mau.
IV. BAN LUAN 4 . 1 . Tuoi, gidi
Theo nghien ciru ciia chiing tdi cho thay tud'i trung binh la 39,4. Tud'i thap nhat la 9, cao nhat la 70. Chidzonga va cpng sy' khi nghien cu'u 282 tru'dng hdp thay tudi mac benh la 35, trong khoang 10-71 tud'i [6]. Trong nghien ciru ciia chung toi nhdm tudi hay gap nhat la tir 21-60 tuoi chiem ty le 73,8%. Cac ket qua cung phit hdp vdi cac tac gia khac [1,5],
Khdi u tuyen nu'dc bpt lanh tinh thu'dng xuat hien d ngu'di tre trong khi cac khdi u ac tinh thu'dng xuat hien d ngu'di ldn tud'i hdn. Trong nghien ciru nay chung tdi thay nhdm tudi thu'dng gap d u lanh tir 21-60 (75,9%), cdn ddi vdi u ac
tinh ldn hdn 40 (72,7%). Tud'i mac benh trung binh ciia hai nhdm lan lu'dt la 37,9 ddi vdi u lanh va 47,3 ddi vdi u ac. Ket qua nay cting phii hdp vdi nghien ciru ciia Han Thi Van Thanh [5].
Trong sd 65 benh nhan chiing tdi gap 27 nam (41,6%) va 38 nU (58,5%), vdi ty le nam;
nu' la 1:1,4. Jones va cdng sy" khi nghien cu'u 741 tru'dng hdp u tuyen nu'dc bot thay ty le nam:nii' la 1:1,4 [7]. Ket qua nay cung tu'dng ty" vdi Chidzonga (1:1,3) [ 6 ] .
4 . 2 . Trieu chu'ng u tuyen nu'dc b p t : Khdi su'ng phdng tai tuyen ddn thuan la trieu chirng xuat hien dau tien d 67,7% ciia u tuyen nddc bpt ndi chung va 100% u tuyen nu'dc bpt chinh. Ty le nay tu'dng tu'vdi nghien ciru ciia tac gia Han Thi Van Thanh (100%) [5], Tran Thanh Cu'dng (98,2%) [2]. Ty ie nay xuat hien d cac khdi u lanh va ac ti'nh fan Iddt ta 66,7% va 72,7%.
Nudt vu'dng la trieu chiTng thu'dng gap d u tuyen nu'dc bpt phu, Trong nghien ciru ciia chiing tdi trieu chiTng nay gap d 2 3 , 1 % toan the u tuyen nu'dc bpt va 62,5% u tuyen nu'dc bpt phu. Cd 7,7% benh nhan cd trieu chirng ngat
Y HOC VIET NAM THANG 3 - SO 1/2012 mui va chay mau mui trong dd tap trung d cac
khoi u d vdm hong, hdc mui.
Nhij'ng trieu chiTng nay cung la ly do den kham ciia hau het cac benh nhan. Oac biet cd 3 tru'dng hdp bi liet V I I ngoai bien trong nghien ciTu ciia chung tdi vdi ty le chung la 4 , 6 % thi tat ca deu la ung t h u tuyen nu'dc bpt mang tai. Gia tri ciia trieu chiTng lam sang tren la mdt dau hieu gdi y u ae tinh d tuyen nay [ 6 ] .
Trieu chu'ng dau ia trieu chiTng kha quan trpng trong benh hpc u tuyen nu'dc bpt. Trong nghien ciTu nay ciia chiing tdi dau la trieu chiTng ciia 7,4% u lanh va 9 , 1 % u ae tfnh. Theo nghien eu'u cua Chidzonga [6] thi ty le nay d nhdm u ac la 30% cao hdn trong nghien ciTu ciia chiing tdi.
Cd sir khac biet dang ke nay cd the do sd lu'dng benh nhan ciia chiing tdi chu'a cao, mat khac dau la trieu chiTng chii quan cua benh nhan nen viec khai thac thdng tin phan nao bj han che.
Khdi u thuy sau tuyen mang tai khi phat trie'n cd the gay tneu chiTng khd nuot tren lam sang. Chiing tdi phat hien du'dc 1 tru'dng hdp (1,5%) khdi u thuy sau gay khd nudt va khi tham kham thy'c the cd trieu chu'ng u day phong man hau va amydal khau eai, thanh ben hpng nhu' mpt khdi u khoang ben hong. Vu Duy Dung (2004) [3] khi nghien ciTu cac khoi u quanh hong thay cd 5,3% la u tuyen mang tai.
Trieu chiTng toan than ciia khdi u nu'dc bpt ngheo nan va rat It gap trong nghien cu'u cua chung tdi. Chi cd mdt BN cd bieu hien gay siit (1,5%). Tuy nhien nghien ciru khdng the khang djnh du'dc dau hiey gay siit d BN nay cd phai do u gay ra hay khdng.
4 . 3 . Vj t r i u
Sif phan bo ciia u tuyen nudc bpt da dang tirng vi trf tuyen va khac nhau d cac nghien ciTu.
Trong nghien ciTu ciia chiing tdi, u tuyen du'di ham gap d 9,2% tru'dng hdp.
Nghien cifU ciia chiing tdi chi ra rang khdi u xuat phat tir tuyen mang tai chiem mdt ty le ldn nhat (61,3%), nd cung tu'dng tu'vdi cac nghien ciiU ciia nhieu tac gia [1,7]. Cd nhieu nghien ciriJ thay u tuyen nu'dc bot iTiang tai chiem ty le 85-90% [6].
Cac nghien d My va chau Au thay u tuyen nu'dc bpt phu chiem khoang 2 0 % [ 7 ] . Trong nghien ciTu nay khoi u tuyen nu'dc bpt phu chiem t ^ l e 24,6%.
U tuyen nu'dc bot phu cd the gap d rat nhieu vj tri nhu' niem mac mieng, ma, mdi, vdm khau cai, vdm hpng, ldi mdi, man hau,. [ 2 ] . Trong nghien cu'u nay chiing tdi gap 11 tru'dng hdp
(68,75%) u d viing khau cai, d vdm hpng la 3 tru'dng hdp (18,75%). Jone va cdng su khi nghien cu'u 455 tru'dng hdp u tuyen nude bpt phu thay 51,5% d vdm khau cai, 23,5% d mdi, 1 2 , 1 % d niem mac ma va 1,5% d vdm hpng [ 7 ] .
4 . 4 . Oac diem khdi u
Kich thu'dc u trung binh tren lam sang theo nghien ciTu ciia chiing tdi la 3,0cm. Kich thu'dc be nhat 1cm va ldn nhat 6cm. Kich thu'dc khdi u gap nhieu nhat trong khoang 2-4cm. Odi vdi u tuyen nu'dc bpt ehinh ki'ch thu'dc khdi u trung binh la 3,2cm gap chii yeu trong khoang 2- 4cm (81,6%). Ngu'dc lai u tuyen nu'dc bpt phu kich thu'dc trung binh la 2,4em, khong gap tru'dng hdp nao cd kich thu'dc Idn hdn 4cm. Kfch thu'dc trung binh ciia u ac la 3,3em khdng cd sir khac biet dang ke nao so vdi u lanh (3cm).
A/af do u chac trong nghien ciTu ciia chung tdi la 58,5%, mat dd mem 40%. Khdi u ac tydng irng la 72,7% va 18,2%. Khdi u lanh tinh 55,6%
va 44,4%. Cd 1 trUdng hdp mat dp ciTng thi dd la cua u ac tinh. Tuy nhien theo mdt sd tac gia [2,5] cho rang mat dp u khdng cho phep khang djnh ban chat md benh hpc ciia nd.
Danh gia dac diem raniigidi u la rat quan trpng trong tham kham lam sang. Ranh gidi u ro trong nghien cirli chiem ty le 67,7%. Ciing t / le nay d u lanh la 72,2%, u ac la 45,5%. Ranh gidi khdng ro d u ac la 54,5%, cua u lanh la 27,8%.
Tinh chat di dgng ciia khdi u la mdt dau hieu quan trpng khi kham. Trong nghien ciTu nay ty le khdi u di dpng chiem cao nhat 55,4%, han che di dpng 38,4% va 6,2% la khdng di ddng. Di ddng han che va khdng di ddng d nhdm u ac ti'nh la 81,8%, d nhdm u lanh tinh ty le nay la 37%.
Nhu'ng tru'dng hdp u lanh tinh cd ranh gidi khong ro (27,8%), di dpng han che va khdng phan nhieu la nhu'ng tru'dng hdp u tai phat da du'dc dieu tn phau thuat tru'dc d d , u tuyen nu'dc bpt phy va u khoang ben hpng.
Dau hieu tham nhiem da va niem mac gap 4 tru'dng hdp trong dd 2 tru'dng hdp ung thu' tuyen mang tai, 1 tru'dng hdp la u tuyen nu'dc bot phu d man hau va 1 la u tuyen mang tai. Day cung la mpt dau hieu gdi y den sir ac tinh ciia mpt khdi u ac.
V. K I T LUAN
Qua nghien CCTU 65 benh nhan u tuyen nu'dc bpt di/dc chan doan va dieu tri tai benh vien Tai miii hpng trung u'dng chiing tdi cd mdt sd ket
Y HOC VIET NAM THANG 3 - SO 1/2012 luan: Tudi mac benh trung binh la 39,4, u tuyen
nu'dc bot chinh 38,3, u tuyen nu'dc bot phu 42,8.
Hay gap nhdm tudi 21-60 (73,8%). NiJ-gap nhieu hdn nam, ty le nam/nir la 1:1,4. Trieu chiTng lam sang ngheo nan, chu yeu thay khoi su'ng phdng tai tuyen (68%). Nudt vUdng la trieu chirng chii yeu eua u tuyen nu'dc bpt phy (62,5%). Benh gap u d tuyen mang tai (63,1%), u tuyen nUde bpt phu 24,6%, ft gap u tuyen nu'dc bpt du'di ham (9,2%) va u tuyen nu'dc bpt dudi lu'di (3,1%).
TAI UEU THAM KHAO
1. Nguyen Duy Cu'dng (2003) "Nghien CLTU dac diem lam sang, mo benh hoc vS ket qua dieu tri cua u tuyen di/di ham tai benh vien K", Luan van tdt nghiep bac sy ngi tru benh vien chuyen nganh ung thu', TriTdng dai hpc y Ha noi. Ha ngi.
2. Tran Thanh Cu'dng, Nguyen Hong Ri, Tran Van Thiep (1999), "BUdu lanh tuyen mang tai: Dich te hoc-Chan doan-Oieu tri", Y hoc thanh phd HCM - Phu ban chuyen de ung bu'du hoc, 3(4), tr. 125-135.
Vu Duy Dung^ (2004), "Nghien cirtj dac diem lam sang va chan doan hinh anh u khoang quanh hpng gap tai benh vien Tai mui hong trung i/Ong tir 1999-2004", Luan van tdt nghiep bac sy noi tru chuyen nganh Tai mui hgng, Dai hpc y Ha ngi, IHa ngi.
Pham Kim Khanh (1995), "Ung thU tuyen mang tai dieu tn tai benh vien K tir nam 1980-1990", Tap chi Y hoc thu'c hanh - chuyen san ung tiiW hoc thang 11/1995, tr. 26-27.
Han Thj Van Thanh (2001), "Nhan xet dac diem lam sang, mo benh hpc va ket qua piiau thuat CUB u tuyen nUcfc bot mang tai d Benh vien Ktir 1996-2001", Luan van Thac sy y hoc cliuyen nganh ung thu", Tru'dng Dai hoc y Ha Noi, Ha npi.
Chidzonga M.M, Lopez Perez V.M, A. PortiJIa Alvarez A.L (1995), 'Safivary glandtumours in Zimbabwe' report of 282 cases", Int 3. Oral Maxillofac Surg, (24), pp. 293-297.
Jones AV, Craig GT, Speight PM, Franklin CD (2007), 'The range and demographics of salivary gland tumours diagnosed in a UK population" Oral Oncology, (44), pp. 407-417.
NGHIEN CUU TAC DUNG LAM RUNG HOAI TUBONG CUA MO ACID SAUCYUC 40%
D o Kim Stfn*, Tran Ngoc T u a n "
TOM T A T
Nghien ciTu tien hanh tren 30 benh nhan bong sau (23 benh nhan nam, 7nQ'), tuoi tir 2 den 67. Dap thudc nghien ciru duoc ben hanh tir ngay thd 7 den ngay thii 8 sau bong khi hoai tir da chuyen thanh hoai tii kho. Ket qua nghien CLTU cho thay: nhom nghien ciru dap m9 acid salicylic 40% thdi gian rung hoai tiT 6 tre em la 12 ± 2,5 ngay, thdi gian xuat hien mo hat:15
± 2,5 ngay. Vdi ngudi ldn co th6i gian rung hoai tir la 16 ± 2,5 ngay, thdi gian xuat hien mo hat la 18 ± 2,5 ngay. Trong khi do viing chu'ng du'pc dieu tri bang SSD 1 % CO thdi gian ryng hoai tiT va xuat hien mo hat d tre em la 15 ± 2,5 ngay va 19 ± 2,5 ngay. Va tren ngu'di ldn la 23 ± 2,5 ngay va 26 ± 2,5 ngay. Thdi gian ghep da sau bong d ca hai nhom la 22 - 24 ngay Da ghep bam sdng tdt, SU phat trien ciia vi khuan tai be mat vet thu'dng bong cung dUdc danh gia.
Tirichoa: m9 salicylic 40%; vet thu'dng bong.
ABSTRACT
THE STUDY EFFECTIVELY TO FALL NECROZED TISSUE OF OILMENT ACID SALICYLIC 4 0 %
Surgical means of wound management like
* Vien Bong Qudc gia; ** Hoc vien Quan y
tangential excision is not always feasible. Topical wound therapy and dressing remain the mainstay of treatment. In the War Word 2 oiiment acid salydlic had used to cured injuries. Now products still uses in Dermatology widely.A prospective study on 30 patients with full thickness burns treated with acid salicylic 40%. Included 23 male and 7 female. Ages from 2 to 67 years eld. The study carried out at 7* to 8*
postburn when dry necrozed tissue formed. In the cases of full thickness burns treated with acid salicylic 40% showed that: in children necrozed tissue begins to fall away at 12 ± 2,5 days while health granulation tissue appeared at 15 ± 2.5 days. And adult are 23 ± 2.5 days and 26 ± 2.5 days. In the control group treated with SSD 1 % it took 15 ± 2.5 days and 19 ± 2.5 days in children. The number are 23 ± 2.5 days and 26 ± 2.5 days in adultThe role of oilment acid salycihc 40% product as an effective unburn remedy on the bacterial isolates from the wounds of patients were discussed also.
Keywords: oilment acid salycilic 40%; bum wounds.
