chan - canh tay va cac yeu to co lien quan: Hpi nghi noi bet va dai thao dudng toan quoc lan thif VI.
. hiint K.;]., Resendez R. G., Williams K. et ai.
(2004), "National Cholesterol Education Program versus Vi/orld Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study", Circulation, 110(10), pp. 1251-7.
. Parameswaran G. I., Brand K., Dolan ], (2005), "Pulse oximetry as a potential screening tool for lower extremity arterial disease in asymptomatic patients with diabetes mellitus"
Ardi Intern Med, 165(4), pp. 442-6.
. Lee I. T., Lee W. J., Sheu W. H. (2010),
"Metabolic syndrome exacerbating ankie-lDrachiai index in asian type 2 diabetic patients", Angiology.
61(5), pp. 482-6.
DANH GIA TY LE SONG THEM 5 NAM THEO DAC DIEM VI THE KHOI U CUA BENH NHAN UNG THU* DAI T R A N G DIEU TRI BANG P H A U THUAT
KET Hgp HOA CHAT THEO P H A C DO F0LF0X4
L8 Quang Minh*
T O M TAT
D?t van de: Ung thu dai trang dang trd thanh mot van de ciia y te epng dorig, ngay cang dupc quan tam bdi ty le mac va tu' vong cao tren toan the gidi.
0 ^ vdi benh nhan un^ thu dai trang tif sau giai doan I I cd ncjuy cd cao, phau thuat ket hdp vdi phac do iioa (jhat ho trd F0LF0X4 dUdc xem la dieu tri tieu chuan.
O Viet Nam cac nghien cifu danh gia kit hdp phau thuat va hoa chat bo trp theo phac do F0LF0X4 chUa nhieu. Phu'dng phap nghien cufu: Nghien ciiu mo ta CO theo doi phan tfch sau can thiep. Ket qua: Danh gia ty le song them toan bd theo dac diem vi the khoi u ciia 69 benh nhan ung thU dai trangdieu tri bang phau thuat ket hdp hoa chat theo phac do F0LF0X4 tai Benh vien da khoa tinh Ha Nam tif 3/2011 den 3/2016 cotudi mac benh trung binh 60,5 ± 9,7. Nam gidi chiem 55,1%. Kiidi u d DT phai 47,8%, DT trai 52,2%. Kfch thudc khdi u tren 5em chiem 62,3 %, dudi 5cm 37,7%. Ty le benh nhan u giai doan III chiem 71%. Ty le song tliem toan bg sau 5 nSm 30,5%.Thdi gian sdng trung btnh ciia nhdm nghien cifu 36,7 ± 3,2 thang.Ty le sdng them toan bg va song them khong benh 5 n3m ciia benh nhanung thu dai trang cd giai doan benh muon, ung thU bieu mo tuyen khong biet hda hoac do biet hoa thap, dp ac tfnh cao, cd di cin hach giamcd y nghla thdng ke. Ket luan: Giai floan b|nh muon, ung thU bleu mo tuyen khong biet hoa hoac dg biet hoa thap, dp ac tinh cao, ed di c3n hachia nhiJng yeu td tien lUdng giamty le song them 5 n3m 6 benh nhan ung thu dai trang.
TlT khoa: Ung thif dai trang, thdi gian song them 5 nam, phac do F0LF0X4.
SUMMARY
REVIEW THE ASSOCIATION BETWEEN 5- YEAR SURVIVAL RATE W I T H
*Benh viin da khoa tinh Ha Nam Chju trach nhi^m chfnh: Le Quang Minh Email: [email protected] Ngay nhan bai: Zllfliill Ngay phan bipn khoa hoc: 5/2/2017 Ngay duyet bai: 27/2/2017
HISTOPATHOLOGICAL CHARACTERISnCS OF COLON CANCER PATIENTS WAS SURGICAL AND TREATMENT BY COMBINED
CHEMICAL F 0 L F 0 X 4 REGIMEN Background: Colon cancer is becoming a matter of public health, is increasingly eoncemed by tlie incidence and mortality worldwide. For colon cancer patients with higherlevel I I grade, surgery combined with support regimen F0LF0X4 chemicals are considered standard treatment. In Vietnam, the combination studies evaluating surgical and chemical adjuvant F0LF0X4 regimen is not much.Method: The study describes the analysis of follow-up after the intervention. Results: Review the whole survivaltime with relation of tumor features of 69 colon cancerpatients treated with surgery combined regimen F0LF0X4 chemicals in General Hospital of Hanam Province beetwenMarch, 2011 and March, 2016;
average age 60.5 ± 9.7. The proportion accounted fbr 55.1% of men. Tumor location: 47.8% on the right colon and 52.2% on the left. Above 5cm tumor size accounted for 62.3% and 37.7% had less tiian 5cm.
The percentage of patients with stage III tumors dominated 7 1 % . Survival rate after 3 years ware 47.5%. Survival rate after 5 years ware 30.5%. The average survival time of 36.7 ± 3.2 months. The rate of whole survival timeand disease-freesun/lval time after 5 yearsof colon cancer patientswith with late stage of disease, giand carcinoma or undifferentiated low grade, high malignant degree, lymph node metastasis has decreased with statistical significance.
Conclusions: l.ate stage disease, gland carcinoma or undifferentiated low grade, high malignant degree, witti lymph node metastasis were prognostic factors reduce the 5-year survival rate in patients with coton cancer.
Keywords: Coton cancer, the 5-year sun/ival, F0LF0X4 chemicals.
I. Di^T VAN OE
Ung thu* dai trang (UTDT) dang trcf thanh mot van d l cua y te cdng dong, ngay cang du'^c quan tam bdi ty !e mac va tif vong cao tren toan the gidi [ 6 ] . Sif ket hdp giifa phau thuat va hoa
TAP CHI Y HOC VIET NAM TAP 453 - THAHG 4 - SO 2 - 2017 chat trong dieu tri ung thu' dai trang da du'dc the
hien trong eac khuyen cao dieu tri hien nay. Ddi vdl benh nhan ung t h u dai trang tif sau giai doan I I cd nguy edeao, phau thuat ket hdp vdi phac do hoa chat hd trd F0LF0X4 diidc xem la dieu trj tieu chuan. Cf Viet Nam eae nghien eifu danh gia ket hdp phau thuat va hda chat bo trd theo phac dd F 6 L F O X 4 chu'a nhieu va mdi ehi ddng lai d mdt giai doan nhat djnh ciia benh va thudng du'dc trien khai d eac irung tam y te Idn.
Tai Ha Nam phan tdn benh nhan UT-DT den vien da d sau giai doan I I va difdc phau thuat theo nguyen tac co gang loai bd hoan toan khdi u theo ehi tieu RO va nao vet hach, tap tai lu'u thdng tieu hda dong thdi xac dinh miic do tan rdng di can eiia khdi u tdi eac tang trong 6 bung trong liic p h l u thuat. Sau dd benh nhan diidc ap dung phac do dieu tri hda chat F0LF0X4 theo khuyen eao. Vi vay ctiung toi tien hanh nghien cifu nay nham muc tieu: "Danh gia ty te sdng them 5 nam theo dac diem vi the khdi u cua benh nhan ung thU dai trang dieu t n bang phau thuat ket hdp lida ehat theo phac do F0LF0X4 tai Benh vien da khoa tfnh Ha Nam".
IL €)dl TU'ONG VA PHU'aNG PHAP NGHIEN CU'U 2.1. Odi hi'tfng nghien ciJfu: Bao gom 69 benh nhan ung tiiu' dai trang du'dc phlu thuat va III. KFT QUA NGHIEN CU'U
Bang 3.1. Dac diem chung ciia benh nhan nghien cui/
dieu tri hda ehat bd trd phac dd F0LF0X4 tai Benh vien da khoa tinh Ha Nam tif 3/2011 den 3/2016:
2.1.1. TiSu chuan l&a chgn benh nhan - Benh nhan du'dc ehan doan xae dinh la ung thu' bieu md dai trang bang md benh hpc.
- Du'dc phau thuat va dieu tri hda ehat bd trd phac do F0LF0X4 dil ehu ky tai Benh vien Da khoa tinh Ha Nam.
- Khdng mac cac benh cap tfnh hoac tram trpng khae phoi hdp (suy tim, suy gan, suy than...).
- Danh gia sau md d giai doan I I ed nguy cd cao va giai doan I I I .
- Benh nhan ed ho sd tuU triJ', ddng thcfi cd du cac thdng tin theo ddi dap uhg muc tieu nghien cifu.
2.1.2. TiSu chua'n loai tr&: Benh nhan mac cae tienh ung thU pha hdp khac. Benli nhan bj tif vong khdng lien quan den benh UTDT.
2.2. Phu'dng phap nghien cu'u 2.2.1. Thiet ke nghien c&u: Nghien cifu md ta ed theo ddi phan tfch sau can thiep.
2.2.2. X& ly sdlieu: Sd lieu dUde thu thap rieng eho tdng tru'dng hdp theo mdt mau benh an thdng nhat, dUdc nhap va xii ly bang plian mem SPSS 16.0 for Vi/indows vdi eac thuat toan thdng ke thfeh hdp. Tfnh thdi gian sdng them ciia toan bd 69 benh nhan, theo phu'dng phap Kaplan-I^eyer, dUdc kiem nghiem bang phu'dng phap Hdi quy vdi Test Log-Rank.
Tong so benh nhan Tuoi trung binh Nam qidi (n,%) Vi t r i i<h6i u: £)ai trang phai
Bai tranq trai Kfch thirdc I(h6i u: <5 cm
> 5 c m Hinh the i<hoi u: The siJi
The loet The siJi va loet The tham nhiem Mu'c do xam lan: T2
73 T4
Phu'dng phap phau thuat: Cat dai trang phai Cat doan dai trang ngang
Cat dai trang trai Cat dai trang Sigma Cat dai trang md rong Phau thuat Hartman Thdi gian song them toan bp (Trung binh, 95% CI)
Sau 1 nam Sau 2 nam Sau 3 nam
69 60,5 ± 9,7 38 (55,1%) 33(47,8%) 36 (52,2%) 26 (37,7%) 43 (62,3%) 25 (36,2%) 11 (15,9%) 28 (40,6%) 5 (7,2%) 14 (20,3%) 24 (49,3%) 31 (21,4%) 24 (34,8%) 13 (18,8%) 8 (11,6%) 14 (20,3%) 4 (5,8%) 6 (8,7%) 36,7 ± 3,2 thang (30,4 - 42,9)
62 (89,1%) 43 (52,6%) 41 (47,5%)
Sau 4 nam Sau 5 nam
39 (40,7%) 37 (30,5%) Bang 3.2. So sanh tyieBNty le song them 5 nam theo giai doan benh
Giai doan I I Ilia Illb IIIc
So benh nhan (N = 6 9 ) 20 14 21 14
OS - 5 nam % 100 90,2 68,7 40,0 P = 0,000
DFS - 5 nam % 85,0 75,0 52,6 30 P = 0.000 OS: song them toan bo, DFS: song them khong benh
Bang 3.3 So sanh t^ le BN song them S nam theo themd benh hoc Mo benli hoc
U T B i ^ biet hda thap UTBMT biet hda vira UTBMT bi§t hoa cao LTTBM tuyen nhay UTBM khonq biet hoa
So benh nhan (n = 6 9 ) 14 34 9 10 2
OS - 5 n a m % 21,4 58,8 100 50,0 0 P = 0,012
DFS - 5nam % 0 50,0 88,9 20,0 0 P = 0,003 OS: sdng them toan bo, DFS: sdng them khong benh Nhan xet: Dp biet hda eang thap thi ty le sdng them khdng benh va song them toan bp eang giam vdi p < 0,05. UTBM tuyen nhay la dang ed dp ac tfnh tu'dng ddi eao cd ty te sdng them khdng benh va song them toan bp 5 nam tUdng ifng chi dUdc 20% va 50%. UTBt^l tuyen khdng blet hoa co dd ac tfnh cao nhat, khdng cd benh nhan nao sdng qua 5 nam.
Bang 3.4. So sanh ty le BN sdng thSm 5 nam theo do ac tinh
Dp ac tinh So benh nhan (n = 6 9 ) OS - 5nam % F D S - S n a m % D d a c t i n h eao 26
Dp ac tfnh thap 67,4
OS: sdng them toan bg, DFS: sdng them khong binh Nhan xet: Dp ac tfnh cao ed thdi gian sdng them thap hdn vdi p < 0,05.
Bang 3.5. So sanh ty le BN sdng thSm 5 nam theo tinh tranff di can hjach Tinh trang di can hach I So benh nhan ( N = 6 9 ) OS - 5nam % FDS - 5 nam %
20 80,0
P = 0,000
OS: sdng them toan bg, DFS: sdng them khong binh
Thdi gian (thang)
Bieu dS: Ty le BN song them toan bg theo theo tinh trang di can hach Nhan xet: Wic dp di "can hach cang nhieu ty le sdng them khdng 'benh va sdng them toan bo cang giam vdi p < 0,001.
IV. BAN LUAN
Nghien cifu ciia chung tdi eho thay tudi trung binh mac UTDT la 60,5 ± 9,7, tudi tjiap nhat 39 tuoi, tudi cao nhat 79 tudi, nhdm tuoi hay g§p ta
50 den 69 ehiem 6 8 , 1 % . Ket qua nay ciing ptiiJ hdp vdt phan tdn cac nghien cifu trong nu^c kliac nhu* Tif Thi Thanh Hu'dng cung cdng sy (2012) [ 4 ] . Theo UCQ ty le UTDT tang dan tu sau tuoi 40 va dinh cao d dp tudi 50- 70.
TAP CHi Y HOC VlgT NAM TAP 453 - THANG 4 - SO 2 - 2017 Ve gidl thay LJTDT gap d ea hai gidi. Trong
nghien eifu nay nam gidi chiem 5 5 , 1 % , nU gidi ehiem 44,9%, ty le nam/nu" la 1,26. Oa sd cae tac gia trong nude ghi nhan nam mae UTDT nhieu hdn nu', ty le nay dao dpng tif 1,0 den 1,4.
Nghien euXi cua Tu" Thj Thanh Hu'dng (2012) Benh vien K ty te nam/nif la 1,32. Nhdm benh nhan < 40 tudi ty' le nam nhieu hdn nil'; nhdm >
40 ty te nam ni? tu'dng du'dng. Tuy nhien sif khac biet ehu^ ed y nghla thdng ke [4].
Trong nhien cu'u eua ehung tdi thay the sui chiem 36,2%, the loet chiem 15,9%, the siii loet chiem 40,6%, the tham nhiem 7,2%. Cac ket qua nghien euli trong nu'dc khae ket hdp the sui loet thanh the siii thi ket qua cung tudng tif.
Trong tong so 69 benh nhan nghien eifu thay ty te khol u xam tan den tdp thanh mac (T3) va vu'dt qua thanh mac xam tan ra to chifc xung quanh (T4) la 49,3% va 30,4%. Cd 20,3% sd benh nhan cd khdi u xam lan den tdp cd (T2) va khdng cd benh nhan nao khol u cdn khu trii d Idp niem mac ( T l ) . Dao Thi Tlianh Binh nghien CLfu tai Benh vien K thay giai doan T2 chiem 14,4%, T3 44,4%, T4 40%, chi cd 1 benh nhan (0,01%) d gial doan T l do kham sifc l<hde djnh ky phat hien ra [0]. Cac tac gia nu'dc ngoai eung eho rang mifc dd xam tan u ed gia tri tien lUdng dpc lap [6] [7]
Cho den nayphau thuat ta bien phap ehu yeu de dieu tri UTDT. Nguyen tac phau thuat UTDT la lay het to chifc ung thu, dam bao dien cat an toan, nao vet hach vimg, lap lai lu'u thdng tieu hda. Tiiy theo vi trf khoi u, tinh trang maeh mau, tinh trang hach ma phau thuat vien quyet djnh cat doan dai trang, eat niia dai trang hay cat toan bp dai trang. Theo do phau thuat vien se phai cat khdi u sao cho dien cat each xa khdi u ft ntiat 5 cm va phai nao vet hach theo cudng mach. Ngay nay dieu t n phau thuat UTDT dang cd nhieu thay doi va ap dung nhieu ky thuat mdi, nhu'ng xu hu'dng la tang cu'dng dieu t n bao tdn va dieu trj ket hdp vdi hda trj, m i l n djch va lieu phap nham triing dfch. Trong nghien cifu cua Chung toi toan bd so benh nhan du'dc phau thuat triet can, da sd la cat doan dai trang, ty t | cat dai trang phat cao nhat, cd 23,2% phai md cap cdli tam hau mdn nhan tao sau do md lai thi hai.
Cd 6 tru^dng hdp (8,7%) phai phau thuat Harmann do khdi u dai trang Sigma lan rdng. Sd lu'dng benh nhan phai cat dai trang md rdng thap chi cd 4 tru'dng hdp.
Ty le benh nhan song t h e m 5 nam theo giai do^n benh: Giai doan benh cang eao thi
thdi gian song them cang giam. Ty te song them 5 nam d giai doan I I dat 100%, giam dan d giai doan I l i a , I l l b , IIIc lan lu'dt la 90,2%, 68,7%, 40%,. Sif khae biet ed y nghia thong ke vdi p=
0,000. Tifdng tif ty le sdng them khdng benh 5 nam d benh nhan giai doan I I dat 85,0%, giai doan I l l a la 75,0%, I l l b la 52,6%, IIIc la 30,0%.
Sif khac biet cd y nghTa thdng ke vdi p= 0,000.
Theo y van giai doan I I (tu'dng du'dng DuttesB) ty te sdng tren 5 nam dat 76%; giai doan I I I (tu'dng du'dng Dukes C) t^ le sdng tren 5 nam dat 48%. Phan Van Duyet (2002) bang phu'dng phap theo ddi trife tiep tai Benh vien Viet Tiep Hal Phdng eung xac nhan thdi gian sdng them 3 nam benh nhan giai doan Dukes B dat 63,6%, gia doan Dukes C dat 47% va khdng ed benh nhan Dukes C nao sdng them diidc 3 nam [3].
Pham Hiing CUdng hdi cifu ho sd 213 tru'dng hdp ung thu' dai trang toai earcindm tuyen du'dc dieu tri phau thuat va hda tri tai Benh vien Ung Bu'du Thanh pho Hd Chi Minh tif 10/1995 den 10/2000, ty le sdng edn 5 nam du'dc tfnh bang phu'dng phap Kaplan-I^eier. Ket qua: ti te sdng edn toan bd 5 nam chung cho tat ea mpi giai doan la 56%, ti le sdng edn 5 nam cua cac benh nhan gial doan Dukes B, C va D theo thif t u ta 73%, 39% va 34%. Tac gia cung cho rang giai doan lam sang va phu'dng phap phau thuat la quan trpng nhat quyet djnh den thdi gian sdng them ciia benh nhan [2].
Ty le benh nhan sding them 5 nam theo the mo benh hgc: Nhan djnh ve moi lien quan giiJa the md benh hoc vdi ket qua sdng them Chung tdi thay the khdng biet hda cd ket qua xau nhat, khdng cd benh nhan nao sdng du'dc 5 nam. Ung thu' bieu md tuyen nhay cung cd ket qua tu'dng doi xau, ty le sdng 5 nam chl du'dc 50%. Trong so benh nhan ung thu" bieu md tuyen thi thay ty te sdng toan bp va song khdng benh deu tang dan theo dp biet hda te bao. Khdi u cd dp biet hda cang cao thi dp ac tfnh cang thap va ngUde tai. Dao Thj Thanh Binh nhan djnh khdi u ed dp ac tfnh cang cao thi kha nang tai phat di can cang tdn [0]. Cae tae gia nu'dc ngoai eijng eho rang the md benh hpc va dp biet hda te bao la mpt trong nhiJng yeu t d cd gia trj tien tu'dng dpc tap [6].
Ty Ie benh nh3n sding th§m 5 nam theo mu'c do di can hach: Tuy cd khac nhau ve ket qua sdng them theo mifc dp dt can hach nhu'ng tat ca eac tac gia deu cd chung mpt nhan djnh mu'c dp di can hach ta yeu t d tien tu'dng quan trgng anh hu'dng den ket qua dieu t n . Sd lu'dng
hach phau tfch dutfc sau phau thuat eung la yeu t d can thiet danh gia ehi'nh xae giai doan va tien ludng benh, ddng thdi anh hu'dng den quyet djnh phae dd dieu tri eho benh nhan sau ptiau thuat.
V. KET L U A N
- Tudi mac benh trung binh 60,5 ± 9,7. Ty ie nam gidi chiem 5 5 , 1 % .
- V| h-f khdi u: DT phai 47,8%, DT trai 52,2%.
- Kieh thude khdi u tren Sem chiem 62,3 %, du'di 5cm 37,7%.
- Ty le benh nhan u giai doan I I I chiem ehu yeu (71%).
- Ty le sdng them toan bd sau 5 nam 30,5%.
- Thdi gian song trung binh cua nhdm nghien eifu 36,7 ± 3,2 thang.
- Ty le sdng them toan bd va sdng them khdng benh 5 nam cua benh nhanung thu' dai trang cd giai doan benh mupn, ung thu* bieu md tuyen khdng biit hda hoae dp biet hda thifp, dp ae tfnh cao, CO dl can hach giam a5 y nghTa thong ke.
TAI Ll|U THAIVl K H A O
1. BSo Thj Thanh Binh (201(i),Nhan xet dSe diem lam sanp can lam sang va mot ^ yeu td nguy cd trai phat dl can trong ung thd dai trang tai Benh
Vien K, luan van Thac sy chuyen nganh Ung thtc, Dai hpcY JHa Ngi.
2. Pham Hiing C u ^ g (2003), Caranom dai trang ket qua song con va cac yeu to tten lUdng. Tap diiv hoc Thanh pho Ho OiiMlnh, 7-2003, pp. 172-177.
i. Phan Van Duyet (2002), Nghiai cuU dac di&n lam sang va mot sdhien phap nang cao chat ludng di&j a ngoai Idioa ung did dai tiang iai Benh vi&i Vxt Tiep Haiphong, Luan an Tien sy y hoc. Hoc vien quan y 4. TCr Thj Thanh Hu'dng (2012), Die diem ISm
sang, can lam sang va tac dung phu khong mong mu6n_benh nhan ung ttiU dai trang giai doan III da phau thuat triet can dUde dieu trj bd trd hoa trj phac do F0LF0X4. Tap chi ung thd hoc Viet Nam, 2-2012, pp. 121-124.
5. Nguyen Thanh Tam (2010), Nghiin cuU ton thudng hach trong ung thd hieu mo dai trdc bang dddc phau thuat triet can, Luan an Tien sy y hoc, Hgc vien quan y.
6. Dispell M (2014), How histopathology affiects ttte management of the multidisciplinaiy team,Colorectal Cancer: Diagnosis and Clinical Management, John Wiley & Sons, pp. 69-83.
/ . Nordlinger B, Sorbye H, Debois M, et al.
(2008), Perioperative chemotherapy with F0LFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. THE LANCET, 9617, pp. 1007-1016.
DANH GIA KET QUA PHAU THUAT PLOMBAGE DIEU TRI HO RA M A U DO U NAM PHOI ASPERGILLUS
T O M TAT
Myc tiiu: Danh gia hieu qua ciia phlu thuat Plombage dieu trj ho ra mau do u nam phdi Aspergillus. Ddi ti/^ng va phu'dng phap nghien cuti: Nghien cifu tien cihj tren 66 benh nhan ho ra mau do u nam phoi Aspergillus dirt?c phau thuat Hombage tai Benh vien Pham Ngoc Ttiacti trong thdi gian 5 nam tif 2011 - 2015. Ket qua: Ty le nam/nif la: 3.7, do tudi trung binh la 53,5, thdi gian mo trung binh la^2,33 gid, co 1 tnfdng hdp tif vong ngay thif 10 sau phau thuat do suy ho hap, sau 12 thang eo 96,9%
tnfdng hdp het ho ra mau. Ket lu$n: Phau thuat Plombage la phUdng phap mo an toan, ft bien chuhg nen dUde lUa ehpn ddi vdi nhUng benh nhan cd chifc nang ho hap kem, the trang yeu iiay hinh anh ton
*B$nh vi$n Ph^m Nggc Thach - TP HCI
**B?nh vi4n Quan y 103 Chju trach nhiem ctii'nh: Le Tien Dung Email: [email protected] Ngay nh|n bai: 26/1/2017 Ngay phan bien khoa hoc: 20/2/2017 Ngay duyet bai: 6/3/2oi7
L6 Tien Dung*, Nguyin Van Nam**
thudng bOT CT scanner thupc dang qua phifc tap ma khong the c§t frfia dutfc hc^e ngiy cd ohau thuat qua cao.
T&kh6a:\i nam phoi, phau thuat Plombage SUMMARY
EVALUATE RESULTS OF PLOMBAGE TECHNIQUE FOR TREAT HEMOPTYSIC CAUSED BY PULMONARY ASPERGILLOMA
Objective: Evaluations of outcome of Plombage surgery for treatment of hemoptysis caused by pulmonary aspergilloma. Material and method:' Prospective study on 66 parents with hemoptysis caused by pulmonary aspergilloma were treated with Plombage technique at Pham Ngoc Thach hospital during 5 years from 2011 - 2015. Results; The rate of male/female: 3,7, mean age: 53,5 years, mean operative time : 2,33 hours. The outcome: one patient died postoperatively on day 10*^ because respiratory failure, 96,9% patients with good outcome postoperation 12 month. Conclusion: Plombage technique is safety, small numbers of complications should be apply to patients in poor general condition, diminished respiration or complicated characters on chest CT scan.
/fey worab.'Pulmonaiy aspergiltama, Plombage surgeiy
