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879 November 2015, Vol. 105, No. 11 NOVEMBER 2015 VOL. 105 NO. 11

GUEST EDITORIAL

881 Vaccination saves lives – dare we allow the anti-vaccine lobbyists to prevent it?

L Baker

882 EDITOR’S CHOICE CORRESPONDENCE 884 Modelling cost-effective therapies

R P Abratt

884 Junior medical researchers: A neglected community with great academic potential J Bovijn, A Jacobs, M T Boswell, E du Bruyn, L Bovijn, N Berkowitz

IZINDABA

886 Motsoaledi on ‘tide-turning’ new HIV treatment guidelines 887 Medical aids often their own worst enemies with fraud

889 Council for Medical Schemes braves the tightrope between funders and the poor 890 Private hospitals could turbo-boost public sector reform

BOOK REVIEW

891 The Practitioner’s Guide to Medical Malpractice in South African Law SAMJ FORUM

COCHRANE CORNER

892 Interventions for improving childhood vaccination coverage in low- and middle-income countries

C S Wiysonge, T Young, T Kredo, M McCaul, J Volmink HEALTHCARE DELIVERY

894 Appropriate indications for positron emission tomography/computed tomography:

College of Nuclear Physicians of the Colleges of Medicine of South Africa M Sathekge, J M Warwick, A Doruyter, M Vorster

CLINICAL ALERT

897 Efavirenz as a cause of ataxia in children M P K Hauptfleisch, D P Moore, J L Rodda OPINION

899 Child research in South Africa: How do the new regulations help?

A E Strode, C M Slack EDITORIALS

901 Screening for childhood hearing impairment in resource-constrained settings:

Opportunities and possibilities L Petersen, L Ramma

902 Time for ‘basic antenatal care plus’ in South Africa?

G J Hofmeyr, L Mentrop

904 Family planning in South Africa: Missing essentials and desirables N D Goldstuck

905 Patents and the quality, safety and efficacy of medicines K du Toit, W du Preez, S Padayachee

REVIEW

907 Pre-exposure prophylaxis for South African adolescents: What evidence?

L-G Bekker, K Gill, M Wallace RESEARCH

912 School-based human papillomavirus vaccination: An opportunity to increase knowledge about cervical cancer and improve uptake of screening

G Dreyer, F H van der Merwe, M H Botha, L C Snyman, D Constant, C Visser, J Harvey

SAMJ

EDITOR-IN-CHIEF

Janet Seggie, BSc (Hons), MD (Birm), FRCP (Lond), FCP (SA)

DEPUTY EDITOR

Bridget Farham, BSc (Hons), PhD, MB ChB EDITORS EMERITUS

Daniel J Ncayiyana, MD (Groningen), FACOG, MD (Hon), FCM (Hon) JP de V van Niekerk, MD, FRCR ASSOCIATE EDITORS

Q Abdool Karim, A Dhai, N Khumalo, R C Pattinson, A Rothberg, A A Stulting, J Surka, B Taylor, M Blockman HMPG

CEO AND PUBLISHER Hannah Kikaya

Email: [email protected] MANAGING EDITOR Ingrid Nye TECHNICAL EDITORS Emma Buchanan Paula van der Bijl NEWS EDITOR

Chris Bateman | Email: [email protected] PRODUCTION MANAGER

Emma Jane Couzens DTP & DESIGN Carl Sampson

HEAD OF SALES AND MARKETING Diane Smith | Tel. 012 481 2069 Email: [email protected] JOURNAL ADVERTISING Charles Duke Benru de Jager Reneé van der Ryst Ladine van Heerden ONLINE SUPPORT

Gertrude Fani | Tel. 072 635 9825 Email: [email protected] FINANCE

Tshepiso Mokoena HMPG BOARD OF DIRECTORS Prof. M Lukhele (Chair), Dr M R Abbas, Dr M J Grootboom, Mrs H Kikaya, Adv. Y Lemmer, Prof. E L Mazwai, Dr M Mbokota, Mr G Steyn, Dr G Wolvaardt

ISSN 0256-9574

SAMA website: www.samedical.org Journal website: www.samj.org.za

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1) Pompeo ACL, et al. A randomised, double blind study comparing the effi cacy and tolerability of controlled release Doxazosin and tamsulosin in the treatment of benign prostatic hyperplasia. Int J. Clin Pract Oct 2006;60(10):1172- 1177. 2) Kirby RS, et al. A Combined analysis of double-blind trials of the effi cacy and tolerability of doxazosin-gastrointestinal therapeutic system, doxazosin standard and placebo in patients with benign prostatic hyperplasia. British Journal of Urology International 2001 Feb;87(3):192-200. 3) Carzin XL package insert. 4) Vs. Doxazosin XL originator 4 mg modifi ed release formulation. Department of Health website.http://www.mpr.gov.za - Accessed 21/05/2015.

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880 November 2015, Vol. 105, No. 11

Zebra mother and foal.

Photo: Susan Flegg

917 Missed opportunities for immunisation in health facilities in Cape Town, South Africa*

N Jacob, D Coetzee

922 A profile of anti-vaccination lobbying on the South African internet, 2011 - 2013*

R J Burnett, L J von Gogh, M H Moloi, G François

927 Age of diagnosis of congenital hearing loss: Private v. public healthcare sector*

I R T Butler, D Ceronio, T Swart, G Joubert

930 Evaluation of fetal MRI in a South African referral centre*

A Daire, S Andronikou, A Boutall, S Constantatos, C Stewart, S E Candy

934 Depressive and post-traumatic stress symptoms following termination of pregnancy in South African women: A longitudinal study measuring the effects of chronic burden, crisis support and resilience*

U Subramaney, G E Wyatt, J K Williams, M Zhang, H H Liu, D Chin 939 Childhood cancer incidence in South Africa, 1987 - 2007*

D C Stefan, D K Stones, R D Wainwright, M Kruger, A Davidson, J Poole, G P Hadley, D Forman, M Colombet, E Steliarova-Foucher

CONTINUING MEDICAL EDUCATION GUEST EDITORIAL

948 Adolescent health Q Abdool Karim REVIEW

948 Improving adolescent maternal health C Baxter, D Moodley

ARTICLES

952 Understanding and responding to HIV risk in young South African women:

Clinical perspectives*

R Dellar, A Waxman, Q Abdool Karim

953 Adolescent antiretroviral management: Understanding the complexity of non-adherence*

K Naidoo, A Munsami, M Archary

953 Adolescent HIV treatment issues in South Africa*

H Dawood

954 Human papillomavirus (HPV) vaccination of adolescents in the South African private health sector: Lessons from the HPV demonstration project in KwaZulu-Natal*

N Tathiah, M Naidoo, I Moodley

*Full article available online only.

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