1
May 2006
Hugh-George Patterton, Ph.D.
Abridged Curriculum Vitae
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1. Professional affiliation and contact details
Department of Biotechnology University of the Free State PO Box 339
Bloemfontein 9300 South Africa
Telephone: +27 51-401-2274 Facsimile: +27 51-444-3219 e-mail: [email protected]
2. Education
B.Sc. (Chemistry and Biochemistry), University of Pretoria, 1981
B.Sc. (Hons) (Biochemistry), University of Pretoria, 1982
M.Sc. (Biochemistry), University of Pretoria 1984
Ph.D. (Biochemistry), University of Cape Town, 1991 3. Post-doctoral training
National Institute of Digestive and Degenerative Kidney Diseases (NIDDKD), National Institutes of Health, 1992 - 1996
Department of Biochemistry and Molecular Biology, Pennsylvania State University, 1997 – 1998 4. NRF Rating (2004-2008): B3
5. Prestigious awards
Wellcome Trust International Senior Research Fellow in Biomedical Science, 2000-2004 6. Employment
University of the Free State Associate Professor 2005-present
University of Cape Town Wellcome Trust International Senior Research Fellow and Associate Professor 2000 - 2005
University of the Free State Senior Lecturer 1998 - 2000 Pennsylvania State University Research Associate 1996-1998 7. Grants
Total internationally competitive grants awarded to date: R5,937,000
2
Total of currently active grants awarded: R1,100,000 8. Research supervision
Students graduated as chief supervisor: B.Sc. (Hons): 9; M.Sc.: 4; post-doctoral fellows trained: 2
Students graduated as co-supervisor: B.Sc. (Hons): 2; M.Sc.: 5; Ph.D.: 2 Current students main supervisor: M.Sc.: 4; post-doctoral: 2
9. Teaching experience
Undergraduate: Introduction to DNA (2nd year, quarter course), Molecular biology (3rd year, semester course), Eukaryotic gene regulation (3rd year, quarter course)
Post-graduate: Introduction to bioinformatics, (B.Sc. Hons module), Saccharomyces cerevisiae genetics (B.Sc. Hons module), Writing scientific papers (3 day post-graduate workshop)
10. Bibliography
Peer reviewed papers: 14, average journal impact factor 4.5, average number of citations: 12 Book chapters: 1
Selection from bibliography:
1. Schäfer,G., Smith, E.M. & Patterton, H.G. (2005) The Saccharomyces cerevisiae linker histone Hho1p with two globular domains, can bind to two four-way junction molecules simultaneously. Biochemistry 44, 16766-16775. Journal Impact Factor: 5
2. Chang, C.F., Wai, K.M. & Patterton, H.G. (2004) Calculating the statistical significance of physical clusters of co-regulated genes in the genome: the role of chromatin in domain-wide gene regulation. Nucleic Acids Res. 32, 1798-1807. Journal Impact Factor: 6.6
3. Boa, S., Coert, C. & Patterton, H.G. (2003) Saccharomyces cerevisiae Set1p is a
methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression.
Yeast, 20, 827-835. Journal Impact Factor: 2.0
4. Patterton, H.G. & Graves, S. (2000) DNAssist: the integrated editing and analysis of molecular biology sequences in Windows. Bioinformatics, 16, 652-653. Journal Impact Factor: 6.7
5. Patterton, H.G., Landel, C.C., Landsman, D., Peterson, C.L. & Simpson, R.T. (1998) The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J. Biol. Chem. 273, 7268-7276. Journal Impact Factor: 6.5 6. Patterton, H.G. & Simpson, R.T. (1994) Nucleosomal location of the STE6 TATA box
and Mat2p-mediated repression. Mol. Cell. Biol. 14, 4002 - 4010. Journal Impact Factor: 8.1
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