1. Nurdjanah S. Sirosis Hati dalam Buku Ajar Ilmu Penyakit Dalam , edisi IV
jilid II, Jakarta, Pusat penerbitan Departemen Ilmu penyakit dalam FK UI.,
2006 hal 445-448
2. Kusumobroto O Hernomo, Sirosis Hati, dalam buku ajar Ilmu Penyakit
Hati, edisi I, Jakarta, Jayabadi, 2007, hal 335-345
3. Sohara N, Takagi H, Kakizaki S, Sato K, Mori M, Elevated plasma
adiponectin concentrations in patients with liver cirrhosis correlate with
plasma insulin level, Liver International 2005 ; 25: 28-32
4. Tietge , J.F.Uwe, Boker HW Klaus, Manns P Michael, Bahr J Matthias ,
Elevated circulating adiponectin levels in liver cirrhosis are associated with
liver function and altered hepatic hemodynamics, Am J Physiol Endocrinol
Metab, 2004; 287 : E84-E89
5. Bermejo Lopez Abel, Botas Patricia, Funahashi Tohru et al Adiponectin,
hepatocellular dysfunction and insulin sensitivity, Clinical Endocrinology
(2004) 60, 256-263
6. CK Hui, HY Zhang, NP Lee, et al. Serum adiponectin is increased in
advancing liver fibrosis and declines with reduction in fibrosis in chronic
hepatitis B. Journal of Hepatology August 2007;47(2): 191-202.
7. Kaser S, Moschen A, Ludwiject O, Circulating adiponectin reflects severity
of liver disease but not insulin sensitivity in liver cirrhosis, Journal of
8. Picardi Antonio, D’Avola Delia, Vespasiani umberta et al, Diabetes in
chronic liver disease: from old concepts to new evidence, Diabetes Metab
Res Rev; 2006; 22: 274-283
9. Diez J Juan, Iglesias Pedro, The role of the novel adipocyte-derived
adiponectin in human disease, European Journal of endocrinology (2003)
148; 293-300
10. Perin, PC, Casseder M, Bozzo C, et al, Mechanism of insulin resistance in
human liver cirrhosis. Evidence of a combined receptor and post receptor
defect, J Clin Invest May 1985; 75: 1659-1665
11. A.Bahar, F.Azizi, Insulin resistance and β cell function in patients with chronic hepatitis and impaired glucose tolerance, Int J Endocrinol Metab
2007; 4: 179-187.
12. Bugianesi Elisabetta, McCullough J Arthur, Marceshini G, Insulin
resistance: A Metabolic Pathway to chronic Liver Disease, Hepatology
2005; 42: 987-1000
13. Letiexe MR, Schreen AJ, Gerhard L Paul et al, Insulin secretion,
clearance and action on glucose metabolism in cirrhotic patients. Journal
of clinical endocrinology and metabolism 1993; 1263-1266
14. Arita Y, Kihara S, Ouchi N et al, Paradoxical decrease of an adipocyte
specific protein, adiponectin, in obesity, Biochemical and Biophysical
15. Erding Hu, Peng Lian, and Bruce M. Spiegelman, AdipoQ Is a Novel
Adipose-specific Gene Dysregulated in Obesity, the journal of biological
chemistry, 1996, Vol. 271, No. 18, Issue of May 3, pp. 10697–10703
16. Claudia Menzaghi, Vincenzo Trischitta, and Alessandro Doria, Genetic
influences of adiponectin in insulin resistance, and cardiovascular disease,
Diabetes 2007;56:1198–1209,
17. Ding Xiaokun, Saxena K Neeraj, Lin Songbai et al, The role of leptin and
adiponectin, a novel paradigm in adipocytokine regulator of liver fibrosis
and stellate cell biology, American Journal of Pathology, 6 June 2005, vol
166; 6:1655-1669
18. Kadowaki Takashi, Yamauchi Toshimasa, Adiponectin and adiponectin
receptors Endocrine review ; 2005; 26 (3) : 439-451
19. Petrides.S.Alexander, Vogt Christop, Berge SD, Matthews D, Strohmeyer
G, Pathogenesis of Glucose Intolerance and Diabetes Mellitus in
Cirrhosis, Hepatology; 1993,19: 616-627
20. Kaser S, Moeschen A, Adiponectin and its receptors in non-alcoholic
steatohepatitis, Gut 2005; 54; 117-121
21. Singhal A, Jamieson Nigel, Adiponectin Predicts Insulin resistance but not
endothelial function in Young, Healthy Adolescents, The Journal of Clinical
Endocrinology & Metabolism 90(8) : 4615-4621
22. Taura Naota, Ichikawa Tatsuki, Hamasaki K, et al, Association Between
Liver Fibrosis and Insulin Sensitivity in Chronic Hepatitis C Patients,
23. Alizadeh MHA, Fallahian Farrahnaz, Alafian MS et al, Insulin Resistance
in Chronic Hepatitis B and C, Indian Journal of Gastroenterology 2006 Vol
25:286-288
24. Pegano Claudia, Soardo Giorgio, Esposito Walter et al, Plasma
adiponectin is decrease in nonalcoholic fatty liver disease, European
Journal of endocrinology (2005) 152: 113-118
25. Bugianesi Elisabetta, Pagotto Uberto, Plasma Adiponectin in Nonalcoholic
Fatty Liver is Related to Hepatic Insulin Resistance and Hepatic Fat ontent,
not to Liver Disease Severity, The Journal of Clinical Endocrinology &
Metabolism 90 (6): 3498-3504.
26. Yagmur Eray, Weiskirchen Ralf, Gressner M A, Trautwein C, Tache Frank,
Insulin Resistance in Liver Cirrosis is Not Associated With Circulating
Retinol Binding Protein 4, Diabetes Care volume 30, number 5: 1168-1172.
27. Matsuzawa Y, Funahashi T, Kihara S, Shimomura I. Adiponectin and
Metabolic Syndrome. Arterioscler Thromb Vasc Biol 2004;24:29-33
28. Tacke Frank, Wuetefed T, Horn Rudger et al, High Adiponectin in chronic
liver disease and cholestasis suggest biliary route of adiponectin
excretion in vivo, Journal of Hepatology; 42 (2005) 666-673
29. Kadowaki T, Yamauchi T, Kubota N et al, Adiponectin and adiponectin
receptors in insulin resistance, diabetes, and the metabolic syndrome, the
30. Compean Garcia Diego,Quintana JOJ, Garza MH, Hepatogenous
Diabetes, Current views of an ancient problem, Annals of hepatology,
2009, 8; 13-20
31. Motoshima H, Wu Xiangdong, K Mahdur et al, Differential Regulation of
Adiponectin Secretion from cultured Human Omental and Subcutaneous
Adipocytes: Effects of Insulin and Rosiglitazone, The Journal of Clinical
Endocrinology & Metabolism 87(12):5662–5667
32. Goldstein BJ, Scalia R. Adiponectin: A Novel Adipokine Linking
Adipocytes and Vascular Funtion. J Clin Endocrinol Metab 2004;
89(6):2563-2568.
33. Chandran M, Philips SA, Ciaraldi T, Henry RR. Adiponectin : More than
Just Another Fat Cell Hormone?. Diabetes Care 2003;26(8):2442-2450.
34. Daimon M, Oizumi T, Saitoh T, et al. Decreased Serum Levels of
Adiponectin are a Risk Factor for the Progression to Type 2 Diabetes in
the Japanese Population. Diabetes Care 2003;26:2015-2020
35. Petrides A, Stanley T, Matthews ED et al, Insulin resistance in Cirrhosis :
Prolonged reduction of hyperinsulinemia normalizes insulin sensitivity,
Hepatology, 1998; 28; 1: 141-149
36. Compean D, Quintana JOJ, Gonzales Alberto J, Garza MH, Liver
Cirrhosis and diabetes : Risk factor, pathofisiology clinical implication and
management , World J Gastroenterol 2009, 21 ;15: 280-288
37. Kadowaki T, Yamauchi T. Adiponectin and Adiponectin Receptors.
38. Knobler H, Zhornicky T ,Sandler A et al Tumor Necrosis Alfa induced
insulin resistance may mediate the hepatitis C virus, Diabetes association,
American journal of gastroenterology, 2003; 98, 12: 2751-2756
39. Hotta K, Funahashi T, Arita Y, et al. Plasma Concentrations of a Novel,
Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients.
Arterioscler Thromb Vasc Biol 2000;20:1595-1599.
40. Tsocatzis E, Papatheodoridis VG, Archimandritis JA, The Evolving Role
of Leptin and Adiponectin in chronic Liver Diseases, Am J Gastroenterol
2006;101:2629–2640
41. Lihn AS, Pederson BS, Adiponectin, action,regulation and association to
. LAMPIRAN 2