each group contains of 5 mices. The population used in this experimen is male mices (Rattus norvegicus) that fullfil the inclution criteria, the sample used in this experimen is 25 male mices. Independent variable used is PegaganLeaves sari doses and the dependent variable used in this experimen is the quantity of direct, indirect, and total bilirubin. PagaganLeaves sari is given everyday in the whole 4 weeks orally using small straw, while CCl4 is given through
subcutaneus injection once in two days for 4 weeks.