*Corresponding author. Tel.:#880-721-750041-3118; fax:#880-721-750064.
1Visiting Scientist, National Cancer Institute, Federick, USA
E-mail address:lcc@swadesh.net (M. A. Mosaddik).
Biochemical Systematics and Ecology 28 (2000) 1039}1040
Goniothalamin from
Bryonopsis laciniosa
Linn
(Cucurbiataceae)
M. Ashik Mosaddik
*
, M. Ekramul Haque, M. Abdur Rashid
1
Department of Pharmacy, University of Rajshahi, Rajshahi 6205, BangladeshReceived 11 October 1999; accepted 8 February 2000
Keywords: Bryonopsis laciniasa; Cucurbiataceae; Goniothalamin; Chemotaxonomy
1. Subject and souce
Bryonopsis laciniosaLinn (Cucurbiataceae) is a rare climbing plant, locally known as Shromony (Kirtikar and Basu, 1984; Rahman, 1996). The plant was collected during September 1998 near the village Kakon hat of Borind tract of Rajshahi district, Bangladesh. The plant was identi"ed by Prof. N. Zaman, Dept. of Botany, University of Rajshahi, Bangladesh and a voucher specimen (Voucher specimen no DACB 9400) has been deposited at the Bangladesh National Herbarium.
2. Previous work
No work has been reported on this genus.
3. Present study
The dried whole plant powdered (750 g) was extracted with methanol in a Soxhlet apparatus. The MeOH extract was subjected to fractionation with petroleum ether
(50 ml]5), chloroform (50 ml]3) and ethyl acetate (40 ml]5) successively. From the ethyl acetate fraction goniothalamin (58 mg) was isolated by washing with diethyl ether and "nally puri"ed by PTLC of the ether-solubles on silica gel eluting with toluene : ethyl acetate 1 : 3 followed by recrystallization. The structural elucidation of goniothalamin (C
13H12O2) was con"rmed by comparing the above spectroscopic
data with an authentic sample (Hasan et al., 1995).
4. Chemotaxonomic signi5cance
This is the"rst report on the occurrence of goniothalamin in the genusBryonopsis
of the Cucurbiataceae. Goniothalamin was previously isolated from the bark of
Cryptocarya caloneura(Lauraceae) (Hlubucek and Sizer, 1967), fromGoniothalamus andersonii(Annonaceae) (Jewers et al., 1972), fromGoniothalamus macrophyllus (An-nonaceae) (El-Zayat and Musa, 1985) and from Goniotahlamus sesquipedalis (An-nonaceae) (Hasan et al., 1995).
Acknowledgements
The authors are grateful to Dr. Abdul Gafur, Chairman, Department of Pharmacy, University of Rajshahi for providing lab facilities during the research work.
References
El-Zayat, A.A.E., Musa, A.H., 1985. Tetrahedron 26, 966.
Hasan, C.M., Hussain, M.A., Mia, M.Y., Rashid, M.A., 1995. Fitoterapia 16 (4), 378. Hlubucek, J.R., Sizer, M., 1967. Aust. J. Chem. 20, 2199.
Jewers, P.J., et al., 1972. Phytochemistry 11, 2025.
Kirtikar, K., Basu, R., 1984. Indian Medicinal Plants, Vol-II, Bishen Singh & Mahendra Pal Singh, Dohra Dum-24801, India, 883 pp.
Rahman, M.O., 1996. Bang. J. Plant Tax. 3 (1), 58 pp.
