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: RABU,9 APRIL
2008
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Halaman t / J
S C A N :
Blood pressure
drugs can
prevent heart attack,
stroke even in the elderlv
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S- -"^fr" of *utrn"nt wiih eiiher combo brought blood pres$u€ to an acceptable range ior ?3 pereent oipatients. The ljndinss could shape treatment guidelines due to be rcviewed in a f€s'months, said Dr Daniel Jones. a Universitv of Mississippi blood pressuF specialist and president of the Amedcan Hesri Association.
Docto$ can start with a combination, but few do, part ]y iorlack ofevidence, he said.
Guidelincs also may change to refleci a second studv that found dramatic benefirs fo. ireaiing people in thef 80s, an age when blood pressul€ drugs {ere not known to be sale ''The o!cr-80s arc the most mpidlv expanding segment of ourpopuhlion, and the preva-lenc€ of blood p.essurc dses as peoplc agc. Bcckctt noted.
H i s s t u d \ l s s i g n e d 3,845 older people in Eufope, cbina and s€veml oth$ coun!des to iake the diurtlr. indapamide or dumrny pills plus lhe ACE inhjlritor perindopnl as need-ed to t€ach a goal of 150/80
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lvl'"E9lElr"s!Et-The siudy was stopped last July aft€r monitoN saw that those on the diuretic had 39 percent fewer fatal strckes and 2L percent fewer dearhs from any cause - benefits far exceecling what res€archers
Jones called ii one of the most important studies at the cafttiology meetine and a key advance ior older people. The study did noi includ€ lmil oldcr people in nu$ing homes, who might reap less benefit than healthier peopte,
Also at the conJer€nce ivas the diabetcs drug Actos, whjch sbrulk al1er)' buildups that can lead to heart disease when tested againsi glimepirlde, an older diabeies dne, in a sludy ol 360 diabetics led by Cleveland Clinic cadioloaist Sieven Nis$n
