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Evaluation Pre-hypertension As A Risk Factor Of Acute Coronary Syndrome.

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EVALUATION PRE-HYPERTENSION AS A RISK

FACTOR OF ACUTE CORONARY SYNDROME

Disampaikan di 11thintemational congress-asian society of clinical pathology and laboratory medicine 7th national congress-indonesian association of clinical pathologists,

Jakarta 2010

Sylvia Rachmayati, I da Parwati, Nanan Sekarwana, Rachmat Soelaeman

Bagian Patologi Klinik

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Evaluation Pre-hypertension as a Risk Factor of Acute Coronary Syndrome Sylvia Rachmayati* , Ida Parwati* , Nana Sekarwana* * , Rachmat Soalaeman* * *

* Department of Clinical Pathology – Dr. Hasan Sadikin General Hospital Bandung * * Department of Pediatric - Dr. Hasan Sadikin General Hospital Bandung * * * Department of Internal Medicine - Dr. Hasan Sadikin General Hospital Bandung

The Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment of Hypertension (JNC-7) introduced pre-hypertension (PHT) as a new category defined as systolic blood pressure (SBP) of 120 to 139 mmHg or diastolic blood pressure (DBP) of 80 to 89 mmHg in young adults aged 25 years or older. Acute Coronary Syndrome (ACS) is a cardiovascular disease, divided into 3 types: ST elevation Myocardial Infarction (STEMI), Non-STEMI, and Unstable Angina Pectoris f(lAP), base on Electrocardiogram (ECG), Creatine Kinase-MB(CKMB), and Troponin T. Individuals with PHT are at high risk of developing clinical hypertension than those lower BP levels, and also associated with increased incidence of cardiovascular disease, including ACS. The aim of this study was to evaluate PHT as a risk factor of ACS.

This preliminary descriptive study was using 60 patients with ACS. The result from this study found 6 adults patients (4 men and 2 women) with PHT, aged 42 to 52 years old conducted during April to August 2010. The type of ACS, BP, waist circumference, High Density Lipoprotein-cholesterol (HDL-c), Triglyceride (7U), and fasting blood glucose (FBG) were collected. From 6 patients with ACS, 5 patients had STEM! and 1 patient had UAP. BP among 6 PHT patients were similar (120/ 80 mmHg). High waist circumference only found in 2 women. Low HDL-c found in 3 patients. High TG is not found in all patients. High FBG found in 1 patient.

Conclusion: The possibility of ACS in PHT will be increased If accompanied with another risk factor.

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