Research Area Natural Product Chemistry and Organic Synthesis

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Research Area

Natural Product Chemistry and Organic Synthesis

Exploration of Natural Bioactive Compounds and Natural Product Synthesis

Natural Product Chemistry and Organic Synthesis group has been derived from the interest area of organic chemistry. The research was based on the uniqueness of natural organic compounds that show significant bioactivities and functions. Our project mainly isolates naturally occurring bioactive compounds and determines their structure and bioactivities. Some isolated compounds were partially modified. Later, we also followed another approach to get some new compounds synthetically to gain their activity.

Research Area:

Natural Product Chemistry

(Isolation natural product from Indonesian plants and bioassay)

Research Area:

Natural Product Chemistry

(Isolation natural product from Indonesian plants and antitumor bioassay)

Research area:

1. Synthesis of chalcones and coumarine derivatives 2. Natural products transformation

3. Development of alkene reduction by homogeneous hydrogen transfer

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Research area:

Semi Synthesis of Aceclidine, Natural Product Transformation

Research Roadmap

Research Projects

No Year Project

1 2020 The Potential Use of Active Phenolic Compounds from Jackfruit Plants (Moracea) as Anticancer

2 2020 Dihydrocalcone synthesis through transfer hidrogenation: development of environmentally benign in molecule organic synthesis

3 2019 Synthesis of Active Compounds from Cryptocarya morotaienses (Lauraceae) as Antitumor

4 2019 The Potential Active Compounds of Muntingia calabura plant as antioxidants and antitumor

5 2019 Synthesis of Hantzsch ester, key reagent for transfer hydrogenation reaction on chalcone derivatives

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6 2018 Synthesis of Active Compounds from Cryptocarya morotaienses (Lauraceae) as Antitumor

7 2017 Potential Active Compounds of Legundi Leaves (Vitex trifolia L) as Antioxidants and Antitumor

8 2017 Synthesis of diazoquinolone derivatives as DSSCs

9 2016 Antibacterial-Based Bioactive Compounds from Medang Leaves (Cryptocarya konishii Hayata) for Standardized Herbal Medicine Applications 10 2015

Phytochemicals study and cytotoxic properties of secondary metabolites of Vitex pinnata plant (Verbenaceae) potential food as antitumor model compounds

11 2014

Phytochemicals study and cytotoxic properties of secondary metabolites of Vitex pinnata plant (Verbenaceae) grow in Pangandaran as antitumor model compounds

Publications

N o

Yea

r Title Name of

Journal

Quart

il Category* URL/DOI

1 202 1

Two flavonoid derivatives from the wood of 2Nangkadak (3Moraceae)

AIP Conferenc

e Proceedin

gs

Q4 Conferenc e Proceedin

gs

https://doi.org/10.1063/5.004 1840

2 202 1

Green synthesis of chalcones derivatives

AIP Conferenc

e Proceedin

gs

Q4 Conferenc e

Proceedin gs

https://doi.org/10.1063/5.004 2002

3 202 1

A simple synthesis of Hantzsch esters derivatives as proton donors in the

hydrogenation transfer reaction

AIP Conferenc

e Proceedin

gs

Q4 Conferenc e

Proceedin gs

https://doi.org/10.1063/5.004 2003

4 202 0

Flavonoid derivatives from the leaves of Muntingia calabura l.

Journal of Physics:

Conferenc e Series

Q4 Journal

https://doi.org/10.1088/1742- 6596/1485/1/012030

5 202 0

Two chalcone derivatives from the tree bark of Cryptocarya morotaiense

Research Journal of Chemistry

and Environme

nt (RJCE)

Q4 Journal https://www.worldresearchers associations.com/Archives/R

JCE/

Vol(24)2020/March2020.aspx

6 202 The effect of Rasayan Q2 Journal http://dx.doi.org/10.31788/

(4)

N o

Yea

Journal

Quart

0 various phenolics in p- TsOH-catalyzed solvent-free microwave- assisted synthesis of 4- methyl coumarin derivatives

Journal of Chemistry

RJC.2020.1335808

7 202 0

Five 7-amino-4- methyl-2(1H)- quinolone

derivatives and their

antibacterial and antifungal

evaluation

and Environme

nt (RJCE)

JCE/

Vol(24)2020/April2020.aspx

8 202 0

Microwave- assisted

synthesis of 7- hydroxy-4- methyl coumarin

and its

bioactivity against acne- causing bacteria

IOP Conferenc

e Series:

Materials Science

and Engineerin

g

gs

9 201 9

Kurzichalcolacto ne A and B, two chalcone derivatives from Indonesian Cryptocarya

Journal of Physics:

Conferenc e Series

Q4 Journal https://doi.org/10.1088/1742- 6596/1402/5/055081

10 201 9

Antioxidant and Cytotoxic of α- pyrones from Cryptocarya konishii Hayata

and Environme

nt (RJCE)

JCE/

Vol(23)2019/December2019.

aspx 11 201

9

Synthesis of tannin phenol formaldehyde (Tpf) copolymer from ethyl acetate extract of green tea leaf (Camellia sinensis) as bioadhesive

AIP Conferenc

e Proceedin

gs

https://doi.org/10.1063/1.509 8290

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N o

Yea

Journal

Quart

wood 12 201

7

Cytotoxic chalcones from some

Indonesian Cryptocarya

AIP Conferenc

e Proceedin

gs

https://doi.org/10.1063/1.499 1189

13 201 7

Isolation, amplification and

characterization of foodborne pathogen

disease bacteria gene for rapid kit test

development

AIP Conferenc

e Proceedin

gs

https://doi.org/10.1063/1.499 1181

14 201 0

Phenolic

compounds from Cryptocarya konishii: their cytotoxic and tyrosine kinase inhibitory properties

Journal of Natural Medicines

Q1 Journal https://doi.org/10.1007/s1141 8-009-0368-y

*) Category: Journal/ Conference proceedings