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Accreditation No.: 30/E/KPT/2018

atom indonesia

Exist for publishing the results of research and development in nuclear science and technology EDITOR IN CHIEF

Dr. Julwan Hendry Purba MANAGING EDITOR Drs. Budi Prasetyo, M.T.

EDITORS

Prof. Dr. Zaki Su’ud Nuclear Physics and Reactor Safety, Bandung Institute of Technology, Indonesia Prof. Dr. Terry Mart Theoretical Nuclear and Physics, University of Indonesia, Indonesia

Prof. Dr. Muhayatun Santoso Radiochemistry; Nuclear Analytical Techniques, National Nuclear Energy Agency, Indonesia Prof. Dr. Evvy Kartini Material Science; Neutron Scattering; Condensed Matter Physics, National Nuclear Energy Agency,

Indonesia

Prof. Dr. Mukh. Syaifudin Biomedicine Division, Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency, Indonesia

Dr. Hendig Winarno, M.Sc. Radiation; Pharmaceutical Chemistry, National Nuclear Energy Agency, Indonesia Edy Giri R. Putra, Ph.D. Neutron Scattering, Soft Condensed Matter, National Nuclear Energy Agency, Indonesia

Dr. Abu Khalid Rivai, M.Eng Materials; Corrosion and Nuclear Reactor Technology, National Nuclear Energy Agency, Indonesia Imam Kambali, M.Phil., Ph.D. Radiochemistry and Radioisotopes, National Nuclear Energy Agency, Indonesia

Dr. Darmawan Darwis Biomaterials, Radiation Processing of Polymers, Radiation Sterilization and Decontamination of Pharmaceuticals and Healthcare, National Nuclear Energy Agency, Indonesia

Prof. Dr. Malcolm F. Collins Neutron Scattering; Magnetism; Glasses, McMaster University, Hamilton, Canada

Prof. Dr. Shane J. Kennedy Neutron Scattering; Superconductor; Superionic Materials, Australian Nuclear Science and Technology Organization, Australia

Prof. Dr. Philip K. Hopke Nuclear Analytical Methods (XRF, INAA); Environmental Analysis, Clarkson University, New York, USA Prof. Dr. Takashi Sakuma Solid State Physics, Ibaraki University, Japan

Sugawara Takanori, Ph.D. Nuclear Reactor Physics, Japan Atomic Energy Agency, Japan

Prof. Dr. T. Kamiyama Neutron Instrumentation and Materials Energy, High Energy Accelerator Research Organization, Japan Prof. Dr. Shahidan Radiman Nanomaterials and Their Applications, National University of Malaysia, Malaysia

Prof. Dr. Kell Mortensen Head of X-Ray and Neutron Science, Niels Bohr Institute, University of Copenhagen, Denmark Bowen Li, Ph.D. Physics and Astronomy, Engineering, Lanzhou University, China

Prof. Dr. Gerard O’Sullivan Quantum Mechanics, Atomic and Molecular Physics, Applied Optics, Lasers and Photonics, Low Temperature Physics: Superconductivity and Quantum Fluids, Base Einstein Condensation in Cold Gases, University College Dublin, Ireland

Ass. Prof. Chris Ling Solid-state Oxide Chemistry, Magnetism, Ionic Conductivity, Neutron Scattering, Phase Transitions, Modulated Structures, University of Sydney, Australia

Prof. Sun Ming Choi, Ph.D. Neutron and X-ray Scattering Studies of Molecular Self-Assemblies for Nanostructured Functional Materials, Development of Multi-Component Anisotropic Nanoparticle Superlattice and Their Applications, Structure and Dynamics of Biomembranes Interacting with Proteins, Korea Advanced Institute of Science and Technology, Republic of Korea

Dr. Max Audeev Crystal and Magnetic Structural Studies of Inorganic Materials with Neutron and X-ray Scattering And Atomistic, Australian Nuclear Science and Technology Organization (ANSTO), Australian

Prof. Ikuo Kashiwakura, Ph.D. Hirosaki University Graduate School of Health Sciences, Departement of Radiation Science, Japan Prof. Dr. Liem Peng Hong Scientific Computational Division, Nippon Advanced Information Service (NAIS Co., Inc.), 416

Muramatsu, Tokaimura, Ibaraki, Japan PEER REVIEWERS

Prof. Dr. Ir. Efrizon Umar, M.T. Deputy for Nuclear Science and Application of Technology, National Nuclear Energy Agency, Indonesia

Dr. L.T. Handoko, M.Sc. Physics Theory, Indonesian Institute of Sciences, Indonesia

Prof. Sunarno, Ph.D Nuclear Radiation; Nuclear Instrumentation, Gajah Mada University, Indonesia

Dr. Sutanto, M.Eng Polytechnic Institute of Nuclear Technology, National Nuclear Energy Agency, Indonesia Prof. Yasushi Arano Environmental and Bioanalytical Sciences, Chiba University, Japan

Prof. Dr. Michio Yamawaki Nuclear Fuel and Material, Nuclear Fussion Technology, University of Tokyo, Japan Prof. Dr. Kenji Kikuchi Nuclear Materials, Ibaraki University, Japan

Prof. Dr. Stefan Adams Materials Modelling, National University of Singapore, Singapore

Prof. Dr. Fumio Yoshii Radiation Chemistry; Radiation Polymerization, Japan Atomic Energy Agency, Japan Ass. Prof. Dr. Ho Jin Ryu Materials Science and Engineering, Korea Advanced Institute of Science and Technology,

Republic of Korea

Lucille V. Abad, Ph.D. Philippine Nuclear Research Institute (PNRI) LANGUAGE EDITOR

Jos Budi Sulistyo, Ph.D, Dr. Ratiko, M.T., Ir. Sarjono, M. Sc ADMINISTRATIVE OFFICERS

Iis Sustini, A.Md., Dra. Noer’Aida, R. Suhendani, S.IP., Moh. Zen, Heru Susanto, A.Ma., Ajie Noorseto, S.Kom., Moh. Widya, Wenseslaus Roland, Anggiana Rohandi Yusuf, A.Md., Hanida

Publisher : Center for Informatics and Nuclear Strategic Zone Utilization Mailing Address : National Nuclear Energy Agency

Puspiptek Serpong, Tangerang 15314, Indonesia

Phone (+62 21) 7560575, 7562860 ext. 9017, Fax (021) 7560895 Web: http://aij.batan.go.id, E-mail : atomindonesia@batan.go.id Licences : SIT No. 078/Khs/Dit.PP/II. 1a & 75; 24.5.75,

SIC No. B/289-PK/VI/75; 3.6.75

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vol. 46 no. 3 December 2020

C o n t e n t s

Editorial . . . i

The Use of Image Processing and Analysis in Automated Biological Dosimetry D. Ramadhani, M. Syaifudin, S. Purnami and A. Naroeni . . . .. . . 127

Eye Lens Doses Received by Radiation Workers in Interventional Medical Procedures E. Hiswara, D. Kartikasari, H. Sofyan, N. Nuraeni and K.Y.P. Sandy . . . . . . . 135

Calculation of Energy Levels and Reduced Electric Quadrupole Transition Probability for 22F Isotope Using Oxbash Code A.K. Hasan and B.A. Zayed . . . 141

Reactivity Initiated Transient Response of TRIGA with the Progress of Core Burnt F. Haque1 and N.H. Badrun . . . 149

Effects of Gamma Irradiation on Mating Competitiveness of Male Culex quinquefasciatus (Diptera:Culicidae) in Laboratory T. Ramadhani, U.K. Hadi, S. Soviana, Z. Irawati, A. Rahayu and Sunaryo . . . 155

Molecular and in silico Study of TP53 Codon 72 Polymorphism (rs1042522) in a Population Exposed to High Background Radiation in Mamuju-West Sulawesi D. Tetriana, S. Purnami, T. Rahardjo, W. Mailana, S. Nurhayati, E. Pudjadi, S. Tri Widyaningtyas, T. Ishida and D. Ramadhani . . . 163

Finite-Difference Time-Domain Simulations of Radon Transport in Porous Media A. Tayebi1, H. Bezzout, M. El Maghraoui1 and H. El Faylali . . . . 171

Neutronics Assessment of Accident-Tolerant Fuel in Advanced Power Reactor 1400 (APR1400) D. Hartanto, A. Alshamsi, A. Alsuwaidi, A. Bilkhair, H.A. Hukal and M. Zubair . . . 177

Authors Index . . . 187

Keywords Index . . . 189

Acknowledgment . . . 193

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Accreditation No.: 30/E/KPT/2018

i

EDITORIAL

Dear reader,

It is a great pleasure to provide you the third issue of Atom Indonesia in 2020, namely Vol. 46 No. 3 (2020). Since SCOPUS and Web of Science (WOS) indexed Atom Indonesia, the number of articles submitted to Atom Indonesia has significantly increased. To retain the quality of the publications, all articles submitted to Atom Indonesia are peer reviewed by qualified editors and reviewers and is supported by a professional administration team.

The Atom Indonesia Vol. 46 No. 3 (2020) contains eight articles discussing various aspects and applications of nuclear science and technology. The contributors of those articles are not only from various national institutions and universities, but also from international institutions.

“The Use of Image Processing and Analysis in Automated Biological Dosimetry” was explored by D. Ramadhani from Doctoral Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia

under collaboration with M. Syaifudin and S. Purnami from Center for Technology of Safety and Radiation Metrology, National Nuclear Energy Agency (BATAN), Indonesia and A. Naroeni from Virology and Cancer Pathobiology Research Center, Faculty of Medicine, Universitas Indonesia, Indonesia. Biological dosimetry based on cytogenetic markers such as dicentric chromosome (DC) and micronuclei (MN) is, until now, the most frequently used method to estimate the radiation dose in the radiological accident event.

Another biomarker that recently gains popularity in biodosimetry is γH2AX. All these three assays are microscope-based biodosimetry techniques, and therefore need manual scoring to estimate the radiation dose. Unfortunately, the manual scoring of these assays is time-consuming and labor-intensive. This article describes how image processing and analysis were applied in automated biodosimetry based on the DC, MN, and γH2AX assays.

“Eye Lens Doses Received by Radiation Workers in Interventional Medical Procedures” was written by E. Hiswara, D. Kartikasari, H. Sofyan, N. Nuraeni and K.Y.P. Sandy from Center for Technology of Safety and Radiation Metrology, National Nuclear Energy Agency (BATAN), Indonesia. The International Commission on Radiological Protection (ICRP) has recently recommended that the occupational dose limit for the eye lens be reduced to 20 mSv per year, averaged over defined periods of 5 years, with no single year exceeding 50 mSv. ICRP clearly states that the recommendations are chiefly based on epidemiological evidence that suggested the eye lens dose threshold for cataract induction revised downwards from 2-5 Gy to about 0.5 Gy. Interventional medical workers are at greater health risk from radiation exposure to eyes as a result of the procedures they undertake than most other medical specialists. An extensive study has been carried out to measure the eye lens doses received by 373 interventional medical radiation workers in twelve large hospitals in Indonesia. This paper reports the measurement of occupational eye lens doses for various types of interventional procedures in radiology and cardiology.

“Calculation of Energy Levels and Reduced Electric Quadrupole Transition Probability for 22F Isotope Using Oxbash Code” was explored by A.K. Hasan and B.A. Zayed from Department of Physics, College of Education for Girls, University of Kufa, Kufa, Najaf Governorate, Iraq. A study on the calculation of energy levels and reduced electric quadrupole transition probability for fluorine-22 isotope using Oxbash Code has been carried out. The shell model and OXBASH was used to calculate the energy levels and probability of quadratic transition B(E2) of the 22F isotope in the SD region through PW, CWH active interactions. A comparison was made between the calculation results and the experimental data.

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“Reactivity Initiated Transient Response of TRIGA with the Progress of Core Burnt” was written by F. Haque from Military Institute of Science and Technology, Mirpur Cantonment, Dhaka, Bangladesh under collaboration with N.H. Badrun from Reactor Physics and Engineering Division, INST, AERE, Ganakbari, Bangladesh. This paper illustrates the effects on safety of TRIGA Mark-II research reactor of Bangladesh at its different steps of core burnt during reactivity induced transient. The modeling and simulation were carried by coupled point kinetics, neutronics, and thermal hydraulics code EUREKA-2/RR based on neutronics data calculated previously by Monte Carlo code for different burnt states of TRIGA core. Three burn steps until 150 MWD have been considered for present analysis, which are regarded here as beginning of cycle (BOC); middle of cycle, MOC (75 MWD); and end of cycle, EOC (150 MWD).

“Effects of Gamma Irradiation on Mating Competitiveness of Male Culex quinquefasciatus (Diptera:

Culicidae) in Laboratory” was explored by T. Ramadhani and S. Sunaryo from Banjarnegara Vector Control Research Unit, National Institute of Health Research and Development, Banjarnegara, Jawa Tengah Indonesia under collaboration with U.K. Hadi and S. Soviana from Entomology Laboratory, Department of Animal Infectious Diseases and Veterinary Public Health, Faculty of Veterinary Medicine - Bogor Agricultural University, Bogor, Indonesia, Z. Irawati and A. Rahayu from Center for Isotopes and Radiation Application, National Nuclear Energy Agency (BATAN), Jakarta, Indonesia. Culex quinquefasciatus is the main vector of lymphatic filariasis in Pekalongan City. Sterile Insect Technique (SIT) can be employed as complementary vector control for filariasis. The key success of this technique depends on the ability of laboratory-reared sterile males to mate with the wild-type females. This research aimed to was to determine the mating competitiveness, fecundity and fertility of sterile males of Cx. quinquefasciatus. The pupae of Cx. quinquefasciatus were gamma irradiated at doses of 60, 70, and 80 Gy, whereas unirradiated pupae were prepared as control. The mosquitoes emerging from the irradiated pupae were found to be able to mate with normal females in the cages.

“Molecular and in silico Study of TP53 Codon 72 Polymorphism (rs1042522) in a Population Exposed to High Background Radiation in Mamuju-West Sulawesi” was written by D. Tetriana, S. Purnami, T. Rahardjo, W. Mailana, S. Nurhayati, E. Pudjadi from Center for Safety Technology and Radiation Metrology, National Nuclear Energy Agency (BATAN), Jakarta Selatan, Indonesia under collaboration with D. Ramadhani from Doctoral Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia S. , Tri Widyaningtyas from Virology and Cancer Pathobiology Research Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia and T. Ishida from Unit of Human Biology and

Genetics, Department of Biological Sciences, Graduate School of Science, University of Tokyo Japan.

The evaluation of the tumor protein p53 (TP53) codon 72 polymorphism (rs1042522) status in a population

exposed to high background radiation was performed in this study. Real-time polymerase chain reaction (Q-PCR) was used to genotype the rs1042522 polymorphism in 100 subjects from Takandeang, Salleto, and

Ahu villages in Mamuju district, West Sulawesi. An in silico study was then conducted to identify the potential effects of the proline substitution associated with this polymorphism on protein stability. The in silico analysis was performed using three different computational tools, namely I-Mutant Suite, iStable, and Protein Variation Effect Analyzer (PROVEAN). Secondary and three-dimensional (3D) structural models for wild-type (WT) and variant TP53 were generated to predict potential structural changes in the protein.

“Finite-Difference Time-Domain Simulations of Radon Transport in Porous Media” was explored by A. Tayebi and M. El Maghraoui from Laboratory of Optoelectronics, Physical Chemistry Materials and Environmental, Faculty of Sciences, Ibn Tofail University, Morocco under collaboration with H. Bezzout and H. El Faylali from Laboratory of Computer Science, Systems and Optimization (Informatics, Systems and Optimization), Faculty of Sciences, Ibn Tofail University, Morocco. In this work, an efficient algorithm, using a finite-difference time-domain (FDTD) technique, is proposed for modeling the variation of radon

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Accreditation No.: 30/E/KPT/2018

iii medium, namely the soil. The numerical results are compared with those of the literature or with the theoretical ones.

“Neutronics Assessment of Accident-Tolerant Fuel in Advanced Power Reactor 1400 (APR1400)”

was written by D. Hartanto, A. Alshamsi, A. Alsuwaidi, A. Bilkhair, H.A. Hukal and M. Zubair from Department of Mechanical & Nuclear Engineering, University of Sharjah, Sharjah, United Arab Emirates.

Safety and reliability are the most desirable conditions that each nuclear power plant should improve. Since the Fukushima Daiichi accident, Accident-Tolerant Fuel (ATF) has been extensively researched to improve the performance of the nuclear fuel system. This paper presents the investigation of the ATF system from a neutronics perspective, which positively reflects on the performance of the APR1400 nuclear power plant.

Several advanced fuel candidates such as UC, U3Si2, and UN, which have better thermophysical properties than current UO2 nuclear fuel, have been considered.

On behalf of Atom Indonesia, I would like to thank you all for your contributions and endless support that have allowed Atom Indonesia to reach an outstanding performance for all the years. This outstanding achievement could not have been reached without great efforts and cooperation from the editors, reviewers, management personnel, authors, and readers.

Editor in Chief

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