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Submission date: 26-Jun-2019
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lntemational
ResearchJoumal of Pharmaq
andMedical
SciencesISSN {(h|ln.t
:5
-3277Potency of Active Compound of Red Galangal
(Alpinia Purpurata K. Schum) in Killing Anopheles Sp. Larvae
Handry DarussalamI, Ni Nyoman Murti2, Meity Albertinas, yona palin{, Noritas
'l-€cturE.1 lrohcllct Kcm.rter- Klhlnantrn 'llnrur. Ar[&plP.!r. 7612J :l.e(.turers.
Pohellcs Kcmotles. Kr[maolro l rmur.
B.lilPah.
76 t 25 rl-cr,trrcrr.Poltcktcr Kcsrcnkcs. X.limanten Tirnur.
Balihe;tr.
76t2jrl -q:lurer!. Irollcltcs Kcmcrtles. KrlrrBorllD -I-imur. t alitpapen. 7612j tl.ecturErAsirt
ncc. Polt *kcr Kcmcntcr. K.limearrn
tinur.
ifaiipapan. zOt2S,l,o/',.r-
Jldona E @ inkc,i.x:deLy
causlh
d..Plu,-,lxrt
pete"&,. *hi.* ts t.aro'ri .dk
t*,o,,o thnrt * dk E,t
.lnod**s
q ln
n:N,L)01t ftla.ta trlaM I:\t@
li,ar l:E ntdil0t
alf,?,l,(n,,l,,nt.n
th. islaid 4*,ro,
nlSot-ga *on"
catdtn 8,drf c.r,Br.dt hot.at
n&
lorlv of lrotltekI
thlt Eeath ).,lad Edt.rpdxa, rc*tt*ah
To &1 rria. ,!* L,tee.\rlatdkn
of ftal Aologal. a @,Eanratun ol8aa
Dl- J nrqd_.:.rt
aI..t4
nLLrdot4 ,t.
,'ds co,ntd.rrr.Ir*
P,nnI,q q
nl. $tthld
.tp h'aohrt.4 Etod\x.
,t<.flh,'i.n ol ta
I.tl,hldan *dt16...,t /on@.{:t,s
ar.b^n t ratn;!tt an,a,i
c.r.cdtt r.n4tn*
,,l. t,Jh hr\tl Loth.*c*
22totx. antdod'r*{'4/J b.et brhr,.ft
25b*'th.
K.d Foloqrl
qr,r*t
t.ll,ark Nrrynto A" .tcrrrr/ ,lAd
Efir Ii \,.1*
col,rtundi
tuLr,b
'.xatrot
6 a
.r, i,ahriottk
klrrtc*-
lnhalarul. Rcd gdotsot (.llpt rre Pn.p*tutaX
Sc,/,,,t. Lo,awd)tx?t
ks q.I
lvrRotr lcrroalaria ir
a
mfccrious discerc ceusrd b_vrdarie p.r.ilcr. stid is trrrrnincd k, tullrlr lh.
Bh lhc biteof
dE Aoo,hclcs+
(lri.r!!o.20l5)
pcnajamP.rr lJtrm
Dl$rrict.l]rer
Kalitnanlrn.t'spccialll in th€ Sotcl lleahh Ccrltcr arcr- Pcrujlln
tlstrict
rs srll en&mic to ln.Loria. thc tolal nshna c.ss thrl oc.u. itr
Itenrjan P'tcr Utrrt Dlslrict l'rom Jrnurn !o Octd!.r 2016
$'hich rlrchcd 5{)() c.!€s (pm\' l;&st Kahmaolrn. 2016) lt l.
t4l
l hc ncrhod
c(mmfth
usEd to c<xtt ol no6qratr) lsn.a. rs through l}cu*
ofchcmicsls $chrs.lritc
(As. ka&. & Anc.rd).
'lhi$ cao c{usc manl problqnsrrch
5s ia.cctici&nxig.rncc
li,
or'crcr)mc this pn$lem. thctl t3i
lol of u$of
nalu.rlpllnt+.rd
pnxixiti!s
l.nicides (Wah]rni. 2ol5) t2t. tetlndqreie is
.
coontry dch in bioditc'3il}, hro$n es tlrelargco pnxluccr of rprces rn the
uuld.
rnc of $irch isluf
planS.l (Kus.iani&
Zah.r. 2015) Rcd galargal rlizoocs carltir
iepooins. utltrirr. oar'(noid3 (Hcrliane.2Oll)
Which (Cmir & Sel\-Irimtrum.20ll)
thcsc cortrFuodr cdt bccomcl,nici&l l7l
tr)lll
I IIl. Mrlll(x)
'thirrypc of Ercorch i3 m
crFimetrt
I'hc phcc ofli
resrsr!;h r*a!
c{lri.rl
out!t
theF.!l Kdimdrrn
lt€{hh Mini!o]'Mcdicd Scieoc..Lrbodo . ltc && ir l'.5r!r4
6-122017 I'hc sllrhlrls crrricd qrt
l,rr
(rrc-sr) Anrl!.ils of Variucc (ANOVA)Tt l:nrsdfi
Proccssrr! crrriri
out6l lhc Mcdrcat sctrxrl o[MulrssIm8n [,ntlersit\ 'l lE nrNcss of cfrcc 1!ll.3.s of rcd
talart,l
rctilc c{xnpdn& i0 tilling Anoy'ocle9 lrnec
csmcd(xt
at rhc l.:!sl Kdim.nlsn llc.lth lrolvtccfniclrlxrrikn
of Hc.l6 I'ohrocJDiotrlll
fu-\llr.Ts Att) l)t*us\t()N'l hc rcarh$ of thc cflcstir'!:tccs ol
tlc
rcdi$irl
usrng 15ItaEs of crlrrct of thc rEd r@t $fuch is di3roh..d in l5 Etl
of
l)MS()ll)..lont
,lladc drluuon usrng $rlsr lo ! cqrccntrsrx|rl ofI mt
ml...l Brg ml.. 2m8
ml.. Imt.
Dl.. 0 5 mB ml-.I lltl I I I\,r,,(n l}.-rdr..,.!r1-h.is.I.
(irr,t r.r ,l{EL\ t
c r',,1 ,ld$0.Er :i
IJ
tDtol :!
In trblc
ItlE
arcngc nrotlih
of Arophclca?
l.an..c isbto*n
stuch har ben c$r..;tcd from .cr, mootosrir*l
* ith c(I}csilfttafir of 0.5mg
rnl-nrtt l.rrd
dcrths of8hfr&.
co€cnh.tion of I
m3
m[. uith 9 lsnac &elhs. cdrcefit stim of 2ng nl. l.n& norirlin
of l4 Irils. cirlcertlllim of .lm8 ml.
trrtlrhnrl
morrrhNof
22l.nE rrd tn
thecocdltrlli(,l
oft mg
mLhn..
no.ralit!.lrr!
25 lanac.'I hc hi8h3st rx)rtelin of la.rrc
$ill
(*cur efter ! (xrl(.entrsl,r)oof t mg
mLltith r t('sl of
25lrnic.
Accrxding toHadfl ltrur!.hm. Nr Nlum.n Murt. Mr!t!.A$qtinl.
Y(lt
Pdlr. r|d Nout!,-po*!
of A(tlE ('(,!rpoond of Rld Gj.oSd (AlFr,.t'urF'|rr K. Scbn) lrl KilliDg A!lT6.,6 Sp
lzx'.. tntatnnt
ntu*
ta.tiE,)"1fU,a,a, a ]kIcot
Scrrnis n,Ut.,.lr.vohEc2.liJl! l.
F.
l-2.2o1e.l:
Intemational
ResearchJoumal of Pharmaq
andMedical
SciencesISSN (lhLnct 25lil,:1277
(l).russahm. Nuryarsluti.
Murjiti. & Muslofi.20l5)
d,c rncrcrlc in c(xrcal'att(rll cqtccnlr&lioD is also folk tf,cd b\rncrc{sing the numhcr ol mrcrobtal deathi IBl.
lt0l
llnre
mtrtlit!
in rhis studv rv.! supporr€d b!.rcs€.rch (lrcrliror.20ll)
dlel rhc lcaf sqrrls cqrtain nrd seFtin.rannin.
llilrmtrds
Fhrqlods*I)r!
u.ith resprtattrr- tosins l-ldoaoid has thc cffcctofcoc4l
bv enrcting inro thc bodv of thc lanoc throu8h rhc ro$piralon, *nrcm s.hrchsill
rt.nceusc nervc &mage and Jims8! to lh. rEspin!.t4 *.'$clo and clusr thc
l.nx
ro bc utr.blc k) brr.thc std crsrrualh rlic.Acc\rrdrot
h'
reic.rEh (Cinrr&
Sei\?nrmgrum.20ti d|.rrannans cin rntcricrc *rrh mosgurrrr lanac rtr drBBlmS
fr,(i
tr<caur: unnins $rll hrnd p.olcrns ln lh. drg6lirE rt rtcm lhrl arc needcti trr morprto hnac for gronl[ so ttal lhe Focesg
of
sbdorpoooof
prorciain
thc digcstitrqseo
bccoorcs drsturbcd SlFnrns c.n rlso rmt lc thc drgcatrtc trrct flocosl|ol m(squito ls^ae 15l.
ll I,
According
to
tD.russrlam. Nun.aslut.Muri .
&Muslofa. 2(115, &rrbrotlcs
krroflor8n
rsrl*
rlurdgclcrrto rtrci
is a ncu$linoc
group\ilh
thL.ddrlro
of .l()'rls.lluorirc to lhc
quinoloocri'lg lllc flotrr
tnolm..rlini .niibiolio is slill recommu ed br:corsc tluorupinollxE hrs! {rsE aI(mi.,obrd
fx,Ncr llis ilr comFr$lc l\ith tt
e\p(rinEnt oflhr3
rudi.
lrtrchrItl
th. porrrrr cdrlr$l ofall lonrcl.Ild
dcrdll0l
lV
(hllliRRta()MMlNlrAIt()|tsFo. othcr rdc.r.hcrs llEro nccd tbr funlEr rElcrrct
o ttc
cllcctir'carclrs
of
comFxrndconFrndr rn lillilt
odE, rhosquito l.noc. Atrrlll
os pure comFrrndi conLincdu
tlE redbrttm bsi len &stdr_Ac xta( )wl 'l:txiMrMr
'Ihanl
You Wecir.c Ib thc
plnrcipanBWto
ltarc Helped -lhccuidcliner
Ard lrh)rrl(iium
Microbiotogl of l hc Saruria& Kcnrcatcs Polrc&kc:RDftR}.t(-ts
s.rsrr,- N A L.di A R_ e llfr. M. 20tr. ClrldiniB of i.rp.dd Tr?t .d l'<td llq.duo, lraar. d IE lit !r.d!d P.l6t-S lr+ll r r'r kbd of 20 I o. S!,n M.dd.i r t-tl A^ ll{. lE. H . a } R tr tidt Atmr tb\tu,i<d.i Rrll rEr( .'l!i\i! of G. milae d n t r. 6 L W,rt A6 o, rtE
lk lcl llhlloh tu*q,s X.!!D MrDr. t-r j
Ctir l; . & S.n--!ru6. E (2oll, T.r tir!'.L. t'Etnfrr. trArtu
la, l.:rl.ir (v d hito) .a.sl. h.rr of Ad6 r.srFr. -tai5:-
60
l{l n() Fr
t;.dyutn.E
(2ut6)trr.
8..Xit.-r.
F|olrno.llL.tl (x[e
l5l ltul,s. Ii
i2ollr f.rt rrrdd tir....t., tl,'rr
,r"rtvlBtsuglrl X!r.! I}rd.i..rto
AJI o,Id.lr 7-6.
PtftlE liA rArtj) C(-Fri&sryort .&ta.r^ -d
Cardr ( ht&!.t Rh^,tr t{'d
Rcd nd qtur.tad!.
t hr(n. I AtFrnd.r.
t. ): ter-m:ltl &!I|. I
r2otart:fG.tlct
ofrr,t*tor o-rrro r*rra
Orl /DEbq
ofs..h rr
Ra{lord
AtF r.Fq! .
Ktttr!
rd
Alrlknc 6
MdH o{ frndlel
W{ru,. lr.€ollr
t{G{D.rsird. o-otr Te fnr tir,.c d
P+.r. tC'-*. P{x}rt Mddfr.ds6l rd
I-..f +rn!r A.dqA.$fli lr* ,'rn.l, t)DFe'rdticB€. :{t
tcEtl 2ot.r).]lt-t2t
ll0|
Ifrrd$. lt d^ ouoFrd!
2olaArhsdd A(oiN d fxrrrc lit rd
Ertrsrrsr M.bto
rt, lcq .Frl.
$+lvLEEr.
A.|s -d P€Joftc Aoi,llE
,6llll (in l,t,
sd]id.i s.hr'b8dn I$tl
-lrrr l.fck,firrtsll.h [lrEl llo!
l.?nr I V'Ei1nrdr) Iahrlpt
r, A.t6 A.t!"n-2 tal t2 6rlItl
Izt
t3t
V
CoN(t_l,sI)NTh€ errr&t of rcd
ClnC
(AlplnrrFtrFrrrtr K.Schum) hasa
lanicidal lctivc mmplxtndi lhotc{,l hll l.nac
ofAnophclcs :p.
2
llidra
lhuscdlm. Nr Nlonl.n Mrfi. Mc'N Atrrrrm!.yo.
p.rin, rrd N6iro. pir...1. of Acrr! c{rcpoun.l or R.d cr l|lSal (ArFn;a Pu.Fr,uK
s.hmr'n K'llirs Arorhdd sp.
tlIr'E.' tikdot.,,r,t
Rr*oft,. Jt,..,wi.{
pr'.,''e:'dd
.vaL.orscxxt t|)t'jl[;t.
Voluo.2.
k$.l. Ip
l-2.2lrle222
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