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Supplemental Table 2: International Classification of Diseases (ICD) codes and descriptions for dementia risk factors and comorbidities

Risk factor/comorbidity Description ICD-9 code ICD-10 code

Smoking

Current or past history of smoking.

Based on patient self-report.

NA NA

Alcohol use disorder

Inpatient and outpatient diagnoses

291x, 303x, 305.0x

F10x

Other substance use disorder

Inpatient and outpatient diagnoses

292x, 304x,

305.2-305.9 F11x-F19x

Cardiovascular disease Inpatient and outpatient diagnoses

Cerebrovascular disease:

433x, 434x, 435x, 436x, 437x

Peripheral Vascular Disease:

440.2x, 443.1, 443.81, 443.89, 443.9

Heart Failure:

402x, 404x, 428x

Coronary Heart Disease:

410x, 411x, 413x, 414x

Cerebrovascular disease:

I63x, I66x, I67x, I68x

Peripheral Vascular Disease:

E08.5x, E09.5x, E10.5x, E11.5x, E13.5x, I70x, I73x, I79x,

Heart Failure:

I11.0, I13.0, I13.2, I50x

Coronary Heart Disease:

I20x, I21x, I22x, I24x, I25x

Hypertension Two outpatient, non-emergency department diagnoses OR

One outpatient,

401x-405x, 437.2

I10, I11, I11.0, I11.9, I12, I12.0, I12.9, I13, I13.0, I13.1, I13.10, I13.11, I13.2, I15, I15, I15.1, I15.2, I15.8, I15.9, I67.4

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non-emergency department diagnosis AND receipt of antihypertensive medication.

Dyslipidemia

One outpatient, non-emergency department diagnosis OR

One prescription of a lipid-lowering medication OR

≥160 mg/dL for low-density lipoprotein (LDL) in laboratory database.

272x, 414.3 E78x

Diabetes mellitus Inpatient and outpatient

diagnoses 250.00, 250.02 E11.9

Obesity

Body mass index

≥30 kg/m2. Based on height and weight measurements.

NA NA

Depression

Inpatient and outpatient diagnoses

296.2x, 296.3x, 296.82, 298.0x, 300.4x, 301.12x, 311x

F32x, F33x, F34x

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