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Program Objectives and Rationale The objective of the proposal is to convert a well-established Purdue Ph.D

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In particular, the Department of Chemistry and Chemical Biology's proximity to the Indiana University School of Medicine facilitates productive collaborations and leverages resources in the medical sciences. At least two members of the committee must be from the Department of Chemistry and Chemical Biology at IUPUI. The Director of Graduate Studies meets with the student and, subject to approval by the Advisory Committee and the Graduate School, determines a study plan.

The student must pass five cumulative exams by the end of the fourth semester (summer semesters do not count). The oral exam consists of a presentation by the student and discussion of the OP and the research progress report. The dissertation is written based on the student's original research and is defended orally as one of the final requirements for the doctorate.

Program in Chemistry will be administered by the Department of Chemistry and Chemical Biology of the Indiana University School of Arts and Sciences. Primary responsibility rests with the Chair of the Department of Chemistry and Chemical Biology and the Director of Postgraduate Studies for the department.

PROGRAM RATIONALE

Introduction

  • Institutional Factors
  • Local, Statewide, National and Global Factors
  • Employment Factors
  • Impact on Other Units and Programs at IUPUI and IUB
  • Planning and Implementation
  • Evaluation and Assessment

A Ph.D program delivered entirely on the Indianapolis campus can only help make this vision a reality. The associate faculty members may serve. multiple roles in the proposed Ph.D. program – providing additional opportunities for doctoral-level courses, serving on dissertation committees, and participating in the training of doctoral students through collaboration with the Chemistry faculty. Associated costs to complete the Ph.D. program includes existing and future faculty to teach and advise doctoral students, an administrative assistant, departmental facilities. computers, analytical and other laboratory instrumentation), teaching support for selected students, annual grants for doctoral students working as teaching assistants and research assistants.

This is critical to supporting recently hired research faculty and those who will come on board in the future. This resulted in the establishment of the Integrated Nanosystem Development Institute and the Center for Membrane Biosciences, centers of excellence founded as IUPUI. The Department of Chemistry and Chemical Biology has a long-standing commitment to involving students in the research enterprise.

Pass figures on the Cumulative Examinations will be collected for the previous year in the summer (Item 6). Doctor of Philosophy (Ph.D.) in Chemistry Offered by the Purdue School of Science on the.

TABLE 1:  PROGRAM ENROLLMENTS AND COMPLETIONS Annual Totals by Fiscal Year (Use SIS Definitions)
TABLE 1: PROGRAM ENROLLMENTS AND COMPLETIONS Annual Totals by Fiscal Year (Use SIS Definitions)

Program Description

  • Program description and objectives
  • Admission requirements, student clientele, and student financial support All applicants must have earned, at the minimum, a four-year baccalaureate degree
  • The program curriculum
  • Form of recognition
  • Needed learning resources
  • Other program strengths

Chemical Biology of the Purdue School of Science is in the midst of a hiring initiative that will bring on board additional research-oriented faculty members. Recently, the School of Natural Sciences has taken over the cost of most of the tuition for postgraduate students. Research advisor, one member of the postgraduate faculty from the student's focus area, and one member of the postgraduate faculty from outside the student's focus area.

Two members of the committee must be from the Department of Chemistry and Chemical Biology. Submission of this document to the Graduate School also establishes the membership of the Graduate Advisor. His/her Graduate Advisory Committee and the faculty member responsible for the seminar program must approve the seminar schedule and content.

The opportunity count begins at the first meeting, usually in the first semester. The oral exam will consist of a student presentation and discussion of the OP and research summary.

Program Rationale

  • Institutional factors
  • Student demand
  • Transferability
  • Access to graduate and professional programs
  • Demand and employment factors

14 are some faculty members in the department who participate in other campus centers such as the Center for Computational Biology and Bioinformatics and the Indiana University Cancer Center. At IUPUI, Chemistry and Chemical Biology provides foundational education for students seeking admission to nursing, dental hygiene, physical therapy and a number of other health-related programs in the Schools of Medicine, Dentistry, Engineering and Technology, Nursing and Health and Rehabilitation Sciences. In addition, we train students at the bachelor's and master's levels for application to on-campus medical and dental schools, as well as pharmacy, optometry, and veterinary medicine programs elsewhere in the state.

We have already seen the impact of such programs over the past twenty-five years on faculty productivity, external funding performance, and the overall intellectual climate of the department. We also recognize the impact these scientists-in-training can have as teaching assistants in ours. The new program will seamlessly replace our current one, so it will not affect other IUPUI units or those elsewhere in the country.

The IU Schools of Medicine and Dentistry and the Purdue programs listed from departments outside of Chemistry have research areas in the standard basic sciences with the obvious emphasis on the appropriate applied areas of human health or agricultural science. There are Indianapolis-area residents with strong interests in graduate education who cannot relocate outside the city for personal reasons.

Program Implementation and Evaluation

Many students are enthusiastic about the understanding of matter at the atomic/molecular level that is a central feature of the chemical sciences. Monitoring the above parameters falls under the responsibilities of the Department Chair, the Director of Graduate Studies, and the Chemistry and Chemical Biology Graduate Admissions Committee. Each year in early fall, recruitment data (items 1 and 2) from the previous year are collected and summarized.

Each annual cohort will be followed through graduation to collect the information for items 9 and 10. Data regarding student research productivity, awards and placement will be followed for three to five years post-graduation to capture program productivity emerging after departure and to allow for a long-term view of career trajectory (Items 7, 8 and 11). Description: An overview of the chemistry of main group and transition elements in which descriptive chemistry is linked to qualitative theories of bonding and structure.

Discussions of the bioorganic chemistry of DNA and RNA including their chemical syntheses, structures, enzymatic. During the course, the role of natural inorganic elements in biology will be studied. How metals are introduced into biological systems as probes and agents will also be addressed.

The course provides a basic overview of the basic principles of the molecular assembly of polymers and biomolecules into supramolecular systems and discusses. Specific topics will also include source determination by isotope ratio mass spectrometry, impurity profiling or genetic analysis, newly introduced analytical methods such as desorption ionization techniques in mass spectrometry, and investigations into canine drug detection mechanisms. This course covers many notable achievements in the field of organometallic chemistry, with particular emphasis on the use of transition metals in synthetic organic chemistry.

The formation of carbon-carbon and carbon-heteroatom (O, N, S) bonds will be investigated through detailed reaction mechanisms and extensive synthetic examples. Traditional screening and lead modification approaches will be discussed, along with the latest developments in drug discovery based on "rational" computer-aided design, combinatorial. Investigate and obtain conditions of the macrocyclization step for the total synthesis of [Dap2, Cys12]-ramoplanin A2 aglycone dimer.

Goodpaster, Ph.D

Positions and Honors

Dissertation: Copper-Dioxygen Complex Mediated Aliphatic C-H Bond and DNA Nucleobase Oxidation (DNA cleavage studies were conducted under the direction of Prof. Steven E. Rokita at the University of Maryland, College Park). 2001 Outstanding Invention of the Year (Life Science) University of Maryland, College Park, MD Award title: Novel copper complexes being tested as anticancer agents. 1992 GuangHua Award Peking University, Beijing, China This award is presented annually by Beijing University to the top 10% of students.

Peer-reviewed publications (in chronological order)

  • ICDDT ‘10

Barton* “Shape-selective targeting of DNA by (phenanthrenequinone diimine) rhodium(III) photocleavage agents” Journal of the American Chemical Society. Long * “Design and synthesis of a versatile DNA-cleaving metallopeptide structural domain” Journal of the American Chemical Society. Long* “Metallopeptide-DNA Interactions: Site Selectivity Based on Amino Acid Composition and Chirality” Journal of the American Chemical Society.

Bleomycin” Abstracts of Papers 191st National Meeting of the American Chemical Society, New York, N.Y.; American Chemical Society: Washington, D.C., 1986;. Lang* "Design and Synthesis of Metal-Binding DNA Recognition Helices" Abstracts of Papers 205th National Meeting of the American Chemical Society, Denver CO; American Chemical Society: Washington, D.C., 1993; INOR 0493. Lang* "Nucleic Acid Binding and Cleavage by an Intercalating Metallopeptide" Abstracts of Papers 205th National Meeting of the American Chemical Society, Denver CO;.

Long* “Synthesis and Study of a Novel Redox-Active Metallopeptide Structural Domain” Abstracts of Papers 207th National Meeting of the American Chemical Society, Washington, D.C.;. Dioxygen-Activated Cobalt-Metallopeptides” Abstracts of Papers 212th National Meeting of the American Chemical Society, Orlando, FL; American Chemical Society: Washington, D.C., 1996; INOR 204. Long* "RNA-Metallopeptide Interactions" Abstracts of Papers 214th National Meeting of the American Chemical Society, Las Vegas, NV;.

Combinatorial Libraries of Ni(II)•Xaa-Xaa-His Metallopeptides Incorporating L- and D-Amino Acids” Abstracts of Papers 221st National Meeting of the American Chemical Society, San Diego, CA.; American Chemical Society: Washington, D. Metallopeptides Containing Modified Proline Residues” Abstracts of Proceedings, 222nd National Meeting of the American Chemical Society, Chicago, IL.; American Chemical Society: Washington, D. Review of the recognition of Ni(II)•Xaa-Xaa-His metallopeptides” Abstracts of Proceedings 227th National Meeting of the American Chemical Society, Anaheim, CA.;.

Metallopeptides” Abstracts, 36th Central Regional Meeting of the American Chemical Society, Indianapolis, IN, USA, June GEN-195. Abstracts, 36th Central Regional Meeting of the American Chemical Society, Indianapolis, IN, USA, June GEN-190. Fluorescent Intercalator Displacement” Abstracts of Papers 228th National Meeting of the American Chemical Society, Philadelphia, PA.; American chemical.

Symposium hosted: A Decade of Peer-Led Team Learning, 232nd Fall Meeting of the American Chemical Society, San Francisco, September 2006. Book Review: Basic Principles and Applications of Molecular Quantum Mechanics, Journal of the American Chemical Society. 2007) Mechanism-based inactivation of benzoyl formate decarboxylase, a thiamine diphosphate-dependent enzyme, Journal of the American Chemical Society.

Minto, National Meeting of the American Chemical Society, Washington, DC Poster, additionally selected for Sci-mix session.

Gambar

TABLE 1:  PROGRAM ENROLLMENTS AND COMPLETIONS Annual Totals by Fiscal Year (Use SIS Definitions)
TABLE 1:  PROGRAM ENROLLMENTS AND COMPLETIONS Annual Totals by Fiscal Year (Use SIS Definitions)

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