Diskusi Topik Psikofarmaka
Pembimbing: dr. Wilson, Sp. KJ Disusun oleh:
Jessica Juniarta Sihombing
Kepaniteraan Klinik Stase Ilmu Kesehatan Jiwa RSJ Provinsi Kalimantan Barat
Fakultas Kedokteran Universitas Tanjungpura 2023
ANTIPSIKOTIK
01
ANTIPSIKOTIK
Obat antipsikotik sering dikenal dengan neuroleptik karena memiliki efek samping gambaran seperti gangguan neurologi (pseudoneurologi). Dikenal juga sebagai major tranquilzer karena memiliki efek sedasi.
Sylvia D. Elvira danGitayantiHadisukanto. BukuAjar Psikiatri. EdisiKetigaJakarta: BadanPenerbitFK UI. 2013.
Klasifikasi Antipsikotik
Berdasarkan cara kerjanya
APG 1 (Tipikal) Dopamine Receptor
Antagonist (DA)
APG 2 (Atipikal) Serotonin Dopamine Receptor Antagonist (SDA)
Stahl, Stephen M. Stahl’s Essential Psychopharmacology Neuroscientific Basis and Practical Application fourth edition. New York. Cambrige Medicine Press. 2013.
FARMAKODINAMIK
Skizofrenia tidak diobati Jalur dopamine mesolimbic hiperaktif Gejala positif seperti delusi dan halusinasi.
Pemberian antagonis D2 (antipsikotik konvensional) memblok dopamine dari reseptor D2 hiperaktivitas berkurang mengurangi gejala positif
Skizofrenia tidak diobati Jalur dopamine mesolimbic hiperaktif Gejala positif seperti delusi dan halusinasi.
Pemberian antagonis D2 (antipsikotik konvensional) memblok dopamine dari reseptor D2 hiperaktivitas berkurang mengurangi gejala positif
Antipsikotik golongan 1 (Tipikal)
Stahl, Stephen M. Stahl’s Essential Psychopharmacology Neuroscientific Basis and Practical Application fourth edition. New York. Cambrige Medicine Press. 2013.
About alcoholism treatment drugs
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Alcoholism treatment drugs
25%
Mercury is a very small planet
Mercury
50%
Venus has a beautiful name
Venus
75%
Mars is actually a cold place
Mars
100%
Neptune is far away from us
Neptune
Alcoholism treatment drugs
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60% 60%
Mercury is a very small planet
Mercury 40% 40%
Venus has a beautiful name
Venus
Alcoholism treatment drugs
25%
Venus is the second planet from the Sun
Venus
75%
Despite being red, Mars is a cold place
Mars
Alcoholism treatment drugs
Sun Mon Thu Wed Thu Fri Sat
01 02 03
04 05 06 07 08 09 10
11 12 13 14 15 16 17
18 19 20 21 22 23 24
25 26 27 28 29 30
Mercury is small
Mercury Venus
Venus is very hotAlcoholism treatment drugs
Mercury is the closest planet to
the Sun and the smallest of them all
Mercury
Venus has a beautiful name and
is the second planet from the
Sun
Venus
Despite being red, Mars is actually a cold place. It's full of iron oxide dust
Mars
Alcoholism treatment drugs
Saturn is not the only planet with rings
Manage mood
Venus has a very beautiful name
Get support
Earth is the only planet with life
Be realistic
Mercury is the smallest planet
Plan ahead
Jupiter doesn’t have a solid surface
Think positive
Mars is actually a very cold place
Reward self Relapse
prevention
Relapse
prevention
Alcoholism treatment drugs
Saturn is not the only planet with rings
Nalmefene
Venus has a really beautiful name
Acamprosate
Jupiter is the biggest planet of them all
Naltrexone
Mercury is the smallest planet
Disulfiram
Earth is the planet where we all live
Topiramate
Mars is actually a very cold place
Baclofen
Mechanisms of action of alcoholism medications
Alcoholism treatment drugs
Saturn is not the only planet with rings
Medication
Venus has a really beautiful name
Treatment
Mars is actually a very cold place
Get support
Mercury is the smallest planet
Medical help
Jupiter is the biggest planet of them all
Make a plan
Alcoholism treatment drugs
Possible side effects
Possible side effects
● Saturn is a gas giant with rings
● Neptune is very far away from the Sun
● Jupiter doesn’t have a solid surface
Disulfiram Disulfiram
● Mercury is a very small planet
● The Sun is the star we orbit around
● Pluto is considered a dwarf planet
Acamprosate Acamprosate
● Despite being red, Mars is very cold
● Earth is the planet where we all live
● Venus has a beautiful name
Topiramate
Topiramate
Alcoholism treatment drugs
Mercury is the smallest planet
Severity of the disorder
Severity of the disorder
Mild
25%
Moderate
50%
Severe
75%
Alcoholism treatment drugs
1 - 7 Days
1 - 7 Days 14 Days 14 Days 2 months - 1 year 2 months - 1 year
Symptoms: Mercury is the closest planet to the Sun
and the smallest one Symptoms: Mercury is the
closest planet to the Sun and the smallest one
Symptoms: Venus has a beautiful name and a very
poisonous atmosphere Symptoms: Venus has a beautiful name and a very
poisonous atmosphere
Symptoms: Despite being red, Mars is a cold place.
It's full of iron oxide dust Symptoms: Despite being
red, Mars is a cold place.
It's full of iron oxide dust
Alcoholism treatment drugs
Actions Sobriety goals Tasks Date:
My reward Thanks
XX / XX / 20XX XX / XX / 20XX
● Mercury is a small planet
● Venus has a beautiful name
● Mercury is a small planet
● Venus has a beautiful name
Earth is the planet where we all live Earth is the planet
where we all live Saturn is not the only planet with rings Saturn is not the only
planet with rings
● Task 01
● Task 02
● Task 03
● Task 04
● Task 05
● Task 06
● Task 07
● Task 08
● Task 09
● Task 01
● Task 02
● Task 03
● Task 04
● Task 05
● Task 06
● Task 07
● Task 08
● Task 09 80%
Despite being red, Mars is cold Despite being red,
Mars is cold
Alcoholism treatment drugs
Medication Reduction of consumption
Relapse prevention
Improvement of quality of life
Acamprosate Yes Yes Yes
Disulfiram Yes Yes No
Naltrexone Yes Yes Yes
Topiramate Yes Yes Yes
Alcoholism treatment drugs
Mercury is the smallest planet
01 01 Phase A
Phase A
Saturn is not the only planet with rings
02 02 Phase B
Phase B
Jupiter doesn’t have a solid surface
03 03 Phase C
Phase C
Venus has a very beautiful name
06 06 Phase F Phase F
Earth is the planet with life
05 05 Phase E Phase E
Mars is actually a very cold place
04 04 Phase D Phase D
Do’s Do’s Don’ts Don’ts Treatment drugs
Treatment drugs
Alcoholism treatment drugs
Saturn is the second-largest planet
in the Solar System Venus is extremely hot, even hotter than Mercury
Jupiter is the biggest planet in the Solar System
Mercury is the smallest planet of them all
Despite being red, Mars is actually a cold place
Neptune is the fourth-largest planet in the Solar System
Alcoholism treatment drugs
Alcohol withdrawal
symptoms Anxiety
Anxiety
Insomnia Insomnia
Tremors Tremors
Nausea
Nausea Headache Headache
Seizures
Seizures
Hallucinations
Hallucinations
Alcoholism treatment drugs
Mercury is a very small planet
Drinking
01 01
Venus has a beautiful name
Craving
02 02
Mars is actually a cold place
Dependence
03 03
Neptune is far away from us
Withdrawal
04 04
Alcoholism treatment drugs
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Venus is extremely hot, even hotter than Mercury
Effectiveness
Mercury is the closest planet to the Sun
Acamprosate Acamprosate
Despite being red, Mars is actually a cold place
Disulfiram Disulfiram
Earth is the third planet from the Sun
Topiramate
Topiramate
Alcoholism treatment drugs
03 03
Mercury is a very small planet
Psychological treatment
02 02
Venus has a toxic atmosphere
Medical treatment
01 01
Earth is the planet with life
Prevention
Alcoholism treatment drugs
Time Activity Time Activity
07:00 Meditation 14:00
08:00 Gym 15:00 Park walk
09:00 Support group 16:00
10:00 17:00
11:00 18:00
12:00 19:00 Therapy
13:00 Cooking class 20:00
Notes
Earth is the third planet from the Sun and the only one that harbors life in the Solar System. This is the planet where we all live
Earth is the third planet from the Sun and the only one that harbors life in the Solar System. This is the planet where we all live
Alcoholism treatment drugs
Young adult alcoholics Young adult
alcoholics Intermediate
familial alcoholism Intermediate familial alcoholism
Young antisocial alcoholics
Young antisocial
alcoholics Functional
alcoholics Functional
alcoholics
Chronic severe alcoholics Chronic severe
alcoholics
Alcoholism treatment drugs
Consequences of alcoholism Consequences
of alcoholism
Mercury is the smallest planet of them all
01 01 Medical Medical
Saturn is not the only planet with rings
02 02 Mental Mental
Venus is extremely hot, hotter than Mercury
03 03 Social Social
Alcoholism treatment drugs
5,1%
Venus has a beautiful name and is the second planet from the Sun.
Venus is a terribly hot planet
Alcohol’s global
impact on mortality
Alcoholism treatment drugs
Side effects of the treatment Side effects of the treatment
Mercury is the smallest planet of
them all
01 01 Nausea Nausea
Despite being red, Mars is actually a
cold place
02 02
Asthenia Asthenia
Venus is the second planet
from the Sun
03 03
Drowsiness Drowsiness
04 04
Earth is the only planet known to
harbor life
Sweating
Sweating
Alcoholism treatment drugs
Saturn is not the only planet with rings
Offer options
Mercury is the smallest planet of them all
Get expert advice
Saturn is not the only planet with rings
Don’t use guilt or beg
Mercury is the smallest planet of them all
Don’t take their responsibility How to help?
How to help?
Alcoholism treatment drugs
Despite being red, Mars is actually a cold place
Detoxification 1 1
Earth is the only planet known to harbor life
Rehabilitation 2 2
Venus is extremely hot, hotter than Mercury
Medication 3 3
4 4
Jupiter is the biggest planet of them all
Support groups
Alcoholism treatment drugs
70%
Acamprosate
Despite being red, Mars is very cold
80%
Naltrexone
Neptune is the fourth-largest planet
80%
Topiramate
Venus is the second planet from the Sun
75%
Disulfiram
Jupiter is the biggest planet of them all
Effectiveness
Effectiveness
Alcoholism treatment drugs
Despite being red, Mars is a cold place
Can’t stop drinking
Mercury is the smallest planet of them all
Drinking more than intended
Saturn is not the only planet with rings
Withdrawal symptoms
Venus has a beautiful name but is hot
Craving alcohol
Alcoholism treatment drugs
Jupiter is a gas giant
25%
Mars is actually cold
75%
Mars 60%
Jupiter 40%
Mercury is a small planet
Mercury
Saturn is the ringed planet
Saturn Summary
Venus has a beautiful name and is the second planet from the Sun. This planet is terribly hot, even hotter than Mercury, and we know that its atmosphere is extremely poisonous
Venus has a beautiful name and is the second planet from the Sun. This planet is terribly hot, even hotter than Mercury, and we know that its atmosphere is extremely poisonous
Alcoholism treatment drugs
1-800-662-4357 https://www.samhsa.gov
National Drug Abuse Hotline National Drug Abuse Hotline
212-870-3400 https://www.aa.org
Alcoholics Anonymous
Alcoholics Anonymous
212-269-7797 https://www.ncadd.org
SAMHSA
SAMHSA
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