Supplemental Digital Content 1, Table that shows individual case characteris;cs.
Controls: Age of death PMI ApoE Gender CERAD BRAAK Figures Brain Region
E04-‐46 40 31 3/4 m 0 II Table 1 Frontal
E05-‐130 52 3 3/4 f B* 0 Table 1 Frontal
E05-‐184 81 20 3/3 m A II Table 1 Frontal
E05-‐74 59 6 2/3 m 0 0 Table 1 Frontal
E06-‐113 20 4.5 4/4 f 0 0 Table 1 Frontal
E06-‐114 53 6.5 4/4 m 0 II Table 1 Frontal
E06-‐41 57 10 3/3 m 0 II Table 1 Frontal
E06-‐45 46 6.5 3/3 f 0 0 Table 1 Frontal
OS02-‐270 87 20.5 3/4 m B II Table 1, Fig. 1 Frontal
OS03-‐394 87 5 2/3 f C III Table 1 Frontal
E05-‐54 64 17 4/4 f C III Table 1 Frontal
OS00-‐23 68 11 3/3 f B* 0 Table 1 Frontal
OS03-‐390 74 7 3/3 f 0 II Table 1 Frontal
OS03-‐299 69 6 3/3 m 0 II Table 1 Frontal
Sporadic AD: Age of death PMI ApoE Gender CERAD BRAAK Age onset Figures Brain Region
E09-‐155 83 5.5 3/4 m C V 76 Table 1 Frontal
E04-‐76 72 30.5 4/4 m C V/VI 65 Table 1 Frontal
E05-‐80 83 8.5 4/4 m C V/VI n/a Table 1 Frontal
OS00-‐14 81 n/a 3/4 m C V 80 Table 1 Frontal
OS03-‐298 93 22 3/3 f C V/VI§ 84 Table 1 Frontal
E04-‐172 87 6 3/4 f C V/VI§ 72 Table 1 Frontal
E05-‐145 87 13 3/4 f C VI 74 Table 1 Frontal
OS00-‐10 84 9 3/4 m C IV 78 Table 1 Frontal
OS00-‐38 92 6 3/3 f C VI 80 Table 1 Frontal
OS01-‐10 87 8 3/4 f C V 79 Table 1 Frontal
OS01-‐11 80 5 3/4 f C VI 75 Table 1 Frontal
OS01-‐115 77 24 3/3 m C V/VI n/a Table 1, Fig 1,3,4 Frontal
OS01-‐128 91 2.5 3/4 f C V/VI 70 Table 1 Frontal
*sparse NP-parietal cx only
OS02-‐209 85 9.5 4/4 f C VI n/a Table 1 Frontal
OS02-‐38 79 6 4/4 m C V/VI§ 73 Table 1 Frontal
OS03-‐300 75 12 4/4 f C VI 60 Table 1 Frontal
OS99-‐27 83 7 3/4 m C VI 75 Table 1 Frontal
§prob V
OS10-‐110 47 42 3/3 m C VI 30 Fig 2 Frontal
UW-‐24 46 3.5 n/a m Freq VI 39 Fig 2 Frontal
UW-‐238 51 <24 n/a f Freq V 41 Fig 2 Frontal
UW-‐241 65 <24 n/a f Freq V 47 Fig 2 Frontal
UW-‐301 37 7 n/a m Freq VI 31 Fig 2 Frontal
UW-‐304 58 <24 n/a m mod.freq V 48 Fig 2 Frontal
UW-‐328 44 17.5 n/a f freq VI 38 Fig 2 Frontal
OS12-‐24 54 5.5 3/3 m C VI 45 Fig 2 Frontal
UW-‐16514 72 n/a n/a f C VI 62 Fig 2 Frontal
CBD
OS00-‐13 62 5 3/3 m Bᵻ II/III 57 Table 2 Frontal
OS03-‐01 78 6.5 3/3 f C IV 75 Table 2 Cingulate
OS02-‐73 44 24 3/4 m 0 II/III 33 Table 2 Frontal
PD/DLB
OS05-‐81 68 15.5 3/3 m 0 II 47 Table 2 Cingulate
OS03-‐392 62 19 3/3 f 0 0 58 Table 2 Cingulate
OS07-‐81 69 19.5 3/3 m 0 II 61 Table 2 Frontal
FTD
OS05-‐200 71 18 3/3 f 0 II 62 Table 2 Frontal
n/a: data not available
AD Presenilin:
AD APP muta;on:
ᵻsparse NP-frontal cx only
OS04-‐155 64 6 3/4 f 0 I 56 Table 2 Frontal
OS04-‐125 61 17.5 3/3 m 0 I 56 Table 2 Frontal
Proteomics:
Control: Age of death PMI ApoE Gender CERAD BRAAK
BLSA-‐1313 92 unk 3/3 f 0 II Figure 5,6 Frontal
BLSA-‐1471 87 unk 2/3 m 0 II Figure 5,6 Frontal
BLSA-‐1517 71 16 4/4 f A II Figure 5,6 Frontal
BLSA-‐2027 86 7 2/3 m 0 IV Figure 5,6 Frontal
BLSA-‐2066 95 17 2/3 m 0 III Figure 5,6 Frontal
AD
BLSA-‐1649 98 20 3/3 m C IV Figure 5,6 Frontal
BLSA-‐1984 92 19 n/a f C VI Figure 5,6 Frontal
BLSA-‐2004 82 23 2/3 m C VI Figure 5,6 Frontal
BLSA-‐2028 83 11 3/4 f C VI Figure 5,6 Frontal
BLSA-‐2032 94 17.5 2/3 f C VI Figure 5,6 Frontal
