Table S1 Clinical information and DDST results of the citrullinemia patients

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Table S1 Clinical information and DDST results of the citrullinemia patients

Patient

No. DOB Date of

LT

Follow- up period

PedsQLTM 4.0 Generic Core Scales^a

DDST results prior to LT DDST results after LT

1 June 23, 2013

April 2,

2015 54m 82

Impression: abnormal, may suffer severe development delay

Personal-Social: 1/10 (p), delay Fine Motor-Adaptive: 1/9 (p), delay Language: 2/12 (p), delay

Gross motor: 1/12 (p), delay

Impression: risky, may suffer mild development delay Personal-Social: 5/5 (p), normal

Fine Motor-Adaptive: 8/9 (p), normal-caution Language: 10/12 (p), caution

Gross motor: 7/8 (p), caution

2 November 30, 2008

January

13, 2016 45m 71 She received DQ test She received DQ test

3 May 3,

2016

February

8, 2017 32m 72

Impression: abnormal, may suffer mild to medium development delay

Personal-Social: 4/8 (p), caution Fine Motor-Adaptive: 4/9 (p), delay Language: 4/8 (p), delay

Impression: abnormal, may suffer mild development delay Personal-Social: 8/12 (p), caution

Fine Motor-Adaptive: 4/7 (p), caution Language: 10/16 (p), delay

Gross motor: 8/10 (p), normal-caution

4 January

27, 2018

January 2,

2019 10m -

Impression: abnormal, may suffer medium development delay

Gross motor: 2/10 (p), delay 5 January 2,

2019

May 7,

2019 6m - Impression: normal

Personal-Social: 4/5 (p), normal

Impression: normal

Personal-Social: 5/8 (p), normal

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DDST: Denver developmental screening test; DOB: date of birth; DQ: developmental quotient; LT: liver transplantation; m: month; p:

pass;

a: PedsQLTM 4.0 Generic Core Scales was conducted within 4 months before the end of follow-up in each patient.

Fine Motor-Adaptive: 5/6 (p), normal Language: 5/7 (p), normal

Gross motor: 7/7 (p), normal

Fine Motor-Adaptive: 5/7 (p), normal Language: 8/8 (p), normal

Gross motor: 5/6 (p), normal