Table S1. DEMOGRAPHIC AND CLINICAL CHARACTERISTICS
Variables All patients (n = 118)
Mean (range) age (years) 72 (65-86)
Mean (range) weight (kg) 59 (38-97)
Sex:
Male 73
Female 45
ASA score:
II 62
III 56
Smoking:
Yes 50
No 68
Chemoradiotherapy
Yes 6
No 112
No comorbidities 78
Comorbidities
Hypertension 24
Diabetes 7
Both 9
Protopathy
Tongue cancer 52
Carcinoma of floor of mouth 17
Gingival cancer 13
Buccal carcinoma 19
Oropharyngeal cancer 10
Carcinoma of palate 7
Abbreviations: ASA = American Society of Anesthesiologists
Table S2. TYPES OF FLAP COMPLICATIONS
Complications n
Surgical:
Partial flap necrosis 3
Total flap necrosis 2
Haematoma 1
Flap infection 1
Ecchymosis 1
Dehiscence 1
Total 9
Medical:
Electrolyte disturbance 3
Pneumonia 2
Renal dysfunction 1
Total 6
Both medical and surgical 0
Table S3. UNIVARIATE REGRESSION ANALYSIS OF CATEGORICAL VARIABLES
Complication (n=15)
No Complication
(n=103) 95% CI
Variables n % n % OR Lower Upper P
Sex:
Female 6 13.3 39 86.7 .874
Male 9 12.3 64 87.7 0.914 0.302 2.765
ASA score:
II 5 8.1 57 91.9 .119
Ⅲ 10 17.9 46 82.1 2.478 0.791 7.762
Smoking:
No 7 10.3 61 89.7 .361
Yes 8 16.0 42 84.0 1.660 0.559 4.926
Chemoradiotherapy
Yes 3 50.0 3 50.0 <.05
No 12 10.7 100 89.3 8.333 1.509 46.013
Comorbidities
No comorbidities 5 6.4 73 93.6 <.01
Hypertension 3 12.5 21 87.5 2.086 0.460 9.455 .340
Diabetes 1 14.3 6 85.7 2.433 0.243 24.337 .449
Both 6 66.7 3 33.3 29.200 5.575 152.927 <.001
Protopathy
Tongue cancer 1 1.9 51 98.1 .137
Carcinoma of floor of mouth 5 29.4 12 70.6 5.321 2.269 21.250 .324
Gingival cancer 3 23.1 10 76.9 7.905 1.441 15.300 .194
Buccal carcinoma 3 15.8 16 84.2 1.804 0.929 9.562 .237
Oropharyngeal cancer 1 10.0 9 90.0 1.064 0.324 5.667 .086
Carcinoma of palate 2 28.6 5 71.4 1.383 0.561 20.400 .069
Blood transfusion:
No 11 11.1 88 88.9 .249
Yes 4 21.1 15 78.9 2.109 0.593 7.501
Urinary volume:
Low rate 1 33.3 2 66.7 .124
Medium rate 3 5.2 55 94.8 2.875 0.246 33.600 .400
High rate 11 16.4 56 83.6 0.314 0.087 1.125 .075
Crystal/kg/hour:
Low rate 3 5.7 50 94.3 <.05
High rate 12 18.5 53 81.5 3.774 1.005 14.166
Colloid/kg/hour:
Low rate 9 17.0 44 83.0 .215
High rate 6 9.2 59 90.8 0.497 0.165 1.500
Colloid& FFP/kg/hour:
Low rate 8 14.5 47 85.5 .577
High rate 7 11.1 56 88.9 0.734 0.248 2.175
Abbreviations: ASA = American Society of Anesthesiologists; OR, odds ratio; CI, confidence interval; FFP, fresh frozen plasma.
Table S4. UNIVARIATE REGRESSION ANALYSIS OF CONTINUOUS VARIABLES
Complication
(n=15) No Complication
(n=103) 95% CI
Variables Mean/ Me
dian SD/ Quar
tile Mean/ Media
n SD/ Quar
tile OR Lower Upper P
Weight, kg 56.5 7.6 59.4 10.7 0.971 0.916 1.029 .318
Age, yr 73.0 4.2 71.8 5.3 1.043 0.943 1.155 .412
Preoperative Hb, g/L 130.9 19.2 136.5 14.4 0.977 0.943 1.012 .188
Preoperative albumin, g/L 39.8 4.5 40.3 3.8 0.967 0.842 1.110 .633 Postoperative Hb, g/L 100.5 16.9 112.4 15.0 0.950 0.914 0.987 .009 Postoperative albumin, g/L 25.2 3.6 29.0 4.1 0.796 0.685 0.925 .003
Blood loss, ml 426.7 221.9 352.4 145.4 1.003 1.000 1.005 .099
Tourniquet time, min 64.3 6.9 52.3 12.9 1.168 1.067 1.279 .001
Operation time, min 385.3 146.9 382.5 113.3 1.000 0.996 1.005 .931
VAS 1 1-2 1 0-1 1.099 0.765 1.580 .609
Crystal during operation, ml 2483.3 918.4 2194.2 617.3 1.001 1.000 1.002 .120 Colloid & FFP during
operation, ml 800.0 394.6 809.7 393.5 1.000 0.999 1.001 .928
Fluids during operation, ml 3216.7 939.5 2966.0 694.0 1.000 1.000 1.001 .216 Crystal in 24 hours, ml 5106.7 695.6 4224.3 699.6 1.002 1.001 1.003 <.001 Colloid in 24 hours, ml 800.0 394.6 809.7 393.5 1.000 0.999 1.001 .928 Fluids in 24 hours, ml 5906.7 682.7 5034.0 778.2 1.001 1.001 1.002 .001
Abbreviations: OR, odds ratio; CI, confidence interval; SD, standard deviation; Hb, hemoglobin;
VAS, visual analogue scale; FFP, fresh frozen plasma.
Table S5. MULTIVARIATE LOGISTIC REGRESSION ANALYSIS.
95% CI
Variables OR Lower Upper P
Comorbidities .004
No Comorbidities
Hypertension 2.4 0.348 16.567 .375
Diabetes 6.954 0.435 111.05 .17
Both 76.256 7.243 802.81 <.001
Postoperative albumin 0.783 0.635 0.966 .019
Crystal in 24 hours 1.002 1.001 1.003 .003
Abbreviations: OR, odds ratio; CI, confidence interval.
