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PDF For the protection of our body from substance. Body has specilised system

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For the protection of our body from different pathogen and harmful

substance. Body has specilised system consisting cell and organ this cell are organ involving protection of deficiency

our body.

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ANTIGEN:

• An antigen , also called an immunogen is a

foreign macromolecule that triggers immune

response and induces antibody production.

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CHARECTERISTICS OF ANTIGEN:

1. Immunogenicity

2. Antigenicity

Circulated by (for the students of Sem. IV):

Dr. Ranajit Kumar Khalua, Assistant Professor, Narajole Raj College

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TYPES OF ANTIGEN ON THE BASIS OF ORDER OF THEIR CLASS:

i. Exogenous antigen

ii. Endogenous antigen

iii. Auto antigen

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EXOGENOUS ANTIGEN:

• Exogenous antigen are antigen that have

entered the body form outside for example, by inhalation, Ingestion of injection. By

endocytosis or phagocytosis, exogenous

antigen are taken into the antigen presenting cells and processed into fragment

• Example : Bacteria, viruses, fungi

Circulated by (for the students of Sem. IV):

Dr. Ranajit Kumar Khalua, Assistant Professor, Narajole Raj College

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ENDOGENOUS ANTIGEN :

Endogenous antigen are signals produce with in own cell the start an immune response.

They alert cytotoxic T cell that a body cell is either infected with a virous, such as

influenza

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AUTOANTIGEN :

Autoantigen is usually a normal protein or

complex of proteins that is recognized by the immune system of patients suffering from a specific autoimmune disease

Circulated by (for the students of Sem. IV):

Dr. Ranajit Kumar Khalua, Assistant Professor, Narajole Raj College

(9)

ON THE BASIS OF IMMUNE RESPONSE :

I. Complete antigen

II. Incomplete antigen

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COMPLETE ANTIGEN:

Substances which can induce anti body formation by themselves and can react specifically with these antibodies

Circulated by (for the students of Sem. IV):

Dr. Ranajit Kumar Khalua, Assistant Professor, Narajole Raj College

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INCOMPLETE ANTIGEN (HAPTENS):

• Substance unable to induce antibody formation on its own but can become immunogenic when covalently linked to proteins, call carrier proteins .

• There are two type

• I. Simple

• II. Complex

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