Cnidarian Zic Genes
3.6 Summary
their response to the concentration of Opa in the nucleus (Clark and Akam 2016). In our analysis of ventral head development, Opa displayed dominant genetic interactions; it also produced dramatic head defects when overexpressed in third instar eye-antennal discs (Lee et al. 2007). This genetic behavior also suggests that Opa concentration influences its function. Understanding the role of concentration in Opa’s transcriptional behavior may clarify how it functions as a regulator of gene expression.
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