TONG HqP, PHAN TICH CAU TRUC VA TINH CHAT PHO

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T(lp chi H,)a hoc, T. 45 (2), Tr. 156 -161,2007

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TONG HqP, PHAN TICH CAU TRUC VA TINH CHAT PHO

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M9T 50 ARYLOXIAXETYLHIDRAZON CUA CARVON

DellTI}a soan5-4-2006

NGUYEN TIEN CONGI,TRAN

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VAN HIENI,NGUYEN THI HoAI THUI IKllOa Haa hoc,TW'fl/g DIISP

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!fa'Chi Mint:

'Kl/()(/ 111)(/ hoc.l"wI)-l/g DHSP II" Nili

SUMMARY

Tell ary/o.\)'(lct'fylh.ydrceollt'.\' of^UIiTOfle hove been sylll/icsi:ed. Their structures hav« been cOJlji'rJlled by IR. 'H-NMR uC-Nl'vlR, Dl:P1' and IliUSS spectra. file spectral data hus been invest iguled.

1- MC)DAU

Carvon hay meruha-Lx-dicn-b-on la thanh phan cua uhieu loai tinh dau, dac biet co nhieu (chiem 23' 60°1< ) uong tinh dau hat thia la [II.

Car von Cling co the du'CJC l()ng hop urlirnoucn 12]. mot hidrocacbon co nhicu lrong linh dau cay co rnui. Carven co trong thanh phan cua nhicu Ioai huong lieu. Cac cong trinh nghien ciru con eho tlH1Y dan xuat cua carven co hoat tinh sinh hoc rat dang chu oj nhu: hoat tinh chong co gfal [3J. hoat tinh lIC che su nay marn va phat trien cua thuc vat [41. Trong thong bao tnroc day [5

J.

mol so trong chung toi da neu len kct qua tong hop va phan tich pho cua mol vai aroylhidrazon cua carvon. Tuy nhicn, phan ling ngl1ng tu giCl'a cac arylox iaxctohidrazit va carven cling nhu tinh chat cua cal' aryloxiaxctylhidrazon tuong ling [hi chua thay co coug trinh naodecapden.

Cal' axil aryloxiaxctic duoc dieu chc tu cae phenol urong ling va axil monocloraxeuc. Este

hoa Cal.' axil bang ctanol sau do clio csie vua

dieu che duoc tac dung voi hidrazin hidrat 50~;(,

chung l('>i thu dUl.Jc cae aryloxiaxclohidrazil tu'ung ling. Sau khi tillh che, die

156

aryloxiaxetohidrazit co nhier do nang chay phu hop voi ^GtC so lieu cia duoc c6ng bo uong cac tui lieu tra cuu.

Boa tan 1,0 mmol arvloxiaxerohidrazit (ArOCIl,CONHNIl,) Hong mot luoug cianol vua du. Them dan tung giqt axit <netic bang vao dung dieh vira thu duoc eho den khi piI cua dung dich dat 5,0 .,. 5,5 rei tiep rue cho vao do

1.0 rnmol carven (ClIlll'4~O).Dun hoi luu hon hop phan ung trong 14 gio. Sau khi d<! nguoi, loc lily ket tua va tinh chebang each kct tinh lai lrong etanol den nhict do nang chay on dinh, Dang chung cua phan ling tao thanh cac hidrazonttl: carven duoc bieu dien nhu sau:

ClIlll,,~() + II,NN HCOCIl/);\r -->

CI"H,,~NNIIC()ClI,()Ar + H,O Ar la C"H,(lJ, 2-CH ,-C"I 11(11), 3-CII,-C"H I(IIl ).

4-CIl,-C,H,(IV), 4-C1-C,HI Vi, 4-Br-C"lI,(VI;.

2-iso-C JL-5-C1I,-C"H,(VII). 2-iso-C

J

1,-4-1-5·

CI 1,-C,,l12( VllIi, I-CI"H/IX)._2-ClIlJ1-,(X).

III -

Kfir QuA

VA TIlAO LUAN Mot so du' kicn ve dicu che vaunh chat cua cac aryloxiaxetylhidrazon duoc dan ra

a

^{bang I.}

So voi ph6 hong ngo<.,u cua Gte aryloxiaxclohidrazit tHong ling, pho hong ngo~ii

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