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APLIKASI PENANDA MOLEKULER PADA PEMULIAAN TANAMAN BARLEY (HORDEUM VULGARE)

Relevansinya dengan Pemuliaan Tanaman

APLIKASI PENANDA MOLEKULER PADA PEMULIAAN TANAMAN BARLEY (HORDEUM VULGARE)

Penanda molekuler kini telah diadopsi secara rutin pada program pemuliaan serealia. Barley merupakan tanaman ideal untuk aplikasi teknologi pemuliaan molekuler, karena

tanaman ini diploid (2n = 14). Tanaman ini memiliki siklus hidup yang singkat dan kultivarnya silang-dalam, sehingga analisis genetik maupun fisiologis mudah dilakukan (Forster et al., 1999). Beberapa spesies sumber, seperti landrace yang beradaptasi secara spesifik dan barley liar (H. spontaneum), tersedia untuk introgresi gen-gen yang diinginkan ke dalam kultivar silang-dalam. Selain itu, barley liar dan landrace semuanya diploid dan dapat diantar-silangkan.

Harus dicatat di sini bahwa barley adalah salah satu spesies tanaman tertua yang diketahui (dari data arkeologi) telah dibudidayakan sejak 8000 tahun SM. Sejarah panjang seleksi telah menjadikan kultivar-kultivar modern cukup seragam. Akan tetapi beberapa sifat yang diinginkan berada pada barley liar yang dapat diintrogresikan ke dalam kultivar. Pendekatan tradisonal adalah mencoba dan mengintroduksi satu sifat dalam satu waktu. Dengan tersedianya penanda molekuler, dan suatu prosedur yang efektif untuk mendapatkan galur-galur doubled-haploid dari kultur antera barley, para pemulia kini membidik introgresi beberapa sifat secara simultan (misalnya sifat toleransi terhadap kekeringan dan resistensi terhadap penyakit embun; resistensi terhadap cereal cyst nematode (CCN); toleransi terhadap boron (BT); resistensi terhadap barley yellow dwarf virus (BYDV) dan embun tepung (Mlo);

efisiensi mangan (Mn); dan gen kerdil Denso).

Dengan keberhasilan teknik pemuliaan molekuler yang telah dibuktikan, para pemulia kini dapat menskrining bahan pemuliaan dalam proporsi yang lebih besar. Akan tetapi, jumlah penanda yang kini ada tidak mencukupi. Dengan upaya kerjasama internasional dan mudahnya penggunaan data secara bersama-sama, dibarengi dengan kemajuan di bidang teknik penanda berbasis PCR, suatu hari nanti tidak mustahil akan tersedia database yang sangat bermanfaat bagi para pemulia tanaman. Melalui seleksi dengan bantuan penanda, lebih sedikit individu yang perlu diskrining di dalam suatu populasi namun memungkinkan untuk memperoleh frekuensi gen yang lebih besar, yang sangat meningkatkan efisiensi program pemuliaan. Penggunaan penanda molekuler untuk silang-balik yang dipercepat kini diterima secara luas, yang memfasilitasi identifikasi dini dan membuang galur-galur yang tidak diinginkan, sehingga mengurangi beban kerja.

Upaya paling awal introgresi sifat-sifat tunggal ke dalam kultivar barley dari spesies liar terhalang oleh fakta bahwa sejumlah sifat yang tidak diinginkan juga terintegrasi dengan sifat- sifat yang diinginkan (Saghai-Maroof et al., 1994). Akan tetapi, informasi terbaru menunjukkan bahwa dengan menggunakan latar belakang genetik yang tepat, beberapa pautan yang tidak diinginkan dapat diputus, dan hal ini akan memungkinkan diperolehnya galur pemuliaan yang tidak mungkin bisa diperoleh tanpa menggunakan peralatan modern. Dengan

mempertimbnagkan begitu banyaknya upaya yang telah dilakukan untuk program pemuliaan seperti itu oleh para pemulia tanaman, didukung oleh berbagai perangkat molekuler yang sangat mengagumkan yang secara terus-menerus diperbaiki, bukan tidak mungkin bahwa tanaman-tanaman pertanian yang benar-benar diinginkan akan dapat diregenerasikan dalam waktu dekat.

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147

Agen alkylating, 87

Cahaya dan pembungaan in vitro, 117,

Ahloowalia, B. S., 94

122-124

Air kelapa, 62, 124

Cahaya dan produksi umbi mikro, 126, 127

Akumulator asam-asam amino, 82 Cappadocia, M., 145 Albinisme, 52

Carlson, P.S., 142

Allard, R. W., 146

Carpenter, C., 42

Amplified fragmented length polymorphism Carter, J.V., 144 (AFLP), 100, 130, 131, 134-136 Casein hydrolysate, 61, 63 Analog basa, 87, 88 Caswell, K.L., 144 Androgenesis, 43, 45-52 Chatani, K., 42 Anggrek, 1, 3, 26, 57, 61, 63, 124 Chlamydomonas, 5, 7 Anggur, mikropropagasi komersial, 27, 31

Clinch, P.E.M., 145 Antera, 2-4, 43-52, 121, 137

Cocking, E.C., 139, 142

Antioksidan, 19

Coen, E.S., 142

Asam absisat (ABA), 120

Colasanti, J., 145 Asparagus, 28, 77, 105, 106 Coleman, S., 145 Auksin. 1, 2, 24, 49, 118, 119 Corbesier, L., 144 Cox, T.S., 145 Baird, E., 146 Cresswell, R.J., 140 Bajaj, Y.P.S., 144, 145 Baker, W.G., 145 Dean, C., 143 Balatkovà, V., 141 Dearing, R.D., 142 Bambu, 119, 121, 123, 124 Debergh, P.C., 140 Baum, M., 146 Dediferensiasi, 2 Bawang putih, 29 de-Fossard, R.A., 140 Belliard, G., 139 de-Guzman, E.V., 141 Bennetzen, J.F., 143 Desikasi, 34,102

Ben-Salem, M., 146 Dickens, C.W.S., 145

Bernier, G., 144, 145 Diferensiasi, 5, 6, 8, 11, 12, 43, 46, 49, 50,

Bhojwani, S.S., 141, 143

118

Biji, 1, 56-58, 61-63, 77, 90, 102, 112, 133. Dinding sel, 13, 62, 65-70, 74, 90. Lihat

Lihat juga berbagai subjek

Embrio

juga Teknologi protoplas

Binder, B.M., 143

Diploid, 43, 51, 93, 94, 137 Bingham, E.T., 143 Dithiothreitol, 113

Biologi, 3, 59, 66, 71, 84, 85, 101, 108, 110, Ditta, G.S., 143 129 Dix, P.J., 142 Bioteknologi, 4, 65, 66 Dodds, J.H., 142, 144 Biyashev, R.M., 146 Donnini, P., 142 Bleecker, A.B., 143 Doyle, S., 142

Booth, A., 146 Drews, J.N., 143

Bourgin, J.P., 139, 141 Dumet, D., 140 Bowman, J.L., 143 Dunwell, J.M., 141 Breznovitis, A., 142

Broers, L., 146 Eksplan untuk pembungaan in vitro, 118-124 Broertjes, C., 140 Eksplan untuk mikropropagasi, 16-21, 23, Buah-buahan, 15, 28-31 30, 35, 36, 39

Elektrofusi, 72 Guha, S., 139, 141

El-Gamal, A.S., 146 Guy, C.L., 144 Eliminasi patogen, 4, 31, 111

Eliminasi virus, 27, 31-33, 114 Hakman, I., 144

Elliot, R., 142 Hall, A.E., 143

Ellis, R.P., 145, 146 Hall, R.D., 142 Embriogenesis somatik, 2, 26 Handley, L.L., 145

Embriogenesis, 2, 26, 39, 46, 49, 50, 64, 91 Haploid, 2, 4, 43-46, 50, 51, 60, 63, 93, 94,

Endomitosis, 51 133, 134, 137

Endotesium, 44 Harada T., 144

Engelmann, F., 140, 141 Harney, M.A., 145 Enkapsulasi untuk kreopreservasi, 104 Havelange, A., 144, 145

Erskine, W., 146 Haward, S., 143

Esch, J.J., 143 Hayes, P., 146

Eshed, H.Y., 143 Haemacytometer Fuchs-Rosenthal, 71 Etilen, 24, 85, 120 Henry, R.J., 143

Eujay, I., 146 Hibridisasi somatik, 65, 75, 77

Hibridisasi, 57, 58, 60, 65, 72, 75, 77, 100 Feldmann, K.A., 143 Hiperhidrasi, 22

Fennel, A., 144 Houssa, C., 145

Fluorescence, 73 Hussey, G., 145

Forster, B.P., 145, 146 Indeksing virus, 26

Fowke, L.C., 144 Ingram, D., 146

Fusi protoplas, 2, 64, 66, 72, 75-78 Inkompatibilitas, 112, 114-116 Iradiasi, 35, 36, 76, 87

Galur sel, 37, 79-82, 84, 90, 94, 96 Isaac, P.G., 146 Gametofit betina, 55, 56 Isozim, 130 Gametofit jantan, 51

Garam, 1, 8, 9, 20, 24, 49, 50, 55, 56, 62, 67, Jarak genetik, 133, 136 83, 84, 98, 99, 108, 114, 121, 122, Jayasankar, S., 142

124, 127 Jean, M., 145

Garam mineral (MS), 1, 121 Jensen, A., 146

Gautheret, R.J., 139, 143 Jerusalem artichoke, 13 Gen, 4, 33, 38, 43, 78-81, 84, 90-93, 96, 97, Jones, J.D.G., 143

101, 129, 133-135, 137 Jones, W.N., 140 Genetika, Mendel, 129

Genom, 38, 45, 75, 76, 79, 90, 91, 95, 97, Kalogenesis, 20 100, 130-132, 134, 135 Kalsium, 13, 104 Genotipe, 15, 28, 29, 34, 37, 45, 50, 64, 72, Kalus tanaman lili, 12

74, 98, 110, 126, 128, 134-136 Kanta, K., 141 Giberelin, 12, 117, 119, 121 Karp, A., 146

Gieel-Nielsen, G., 146 Kartha K.K., 140, 144

Ginogenesis, 43, 45 Kaulogenesis adventif, 20-23

Gleba, Y.Y., 139 Kentang, 30, 31, 33, 77, 82, 86, 90, 98, 103,

Gordon, D.C., 145 106, 125-128

Gottlieb Haberlandt, 1 Keragaman epigenetik, 79, 96. 97

Gray, D.J., 142, 144 Keragaman genetik, 35, 86, 93-95, 97, 98,

Groose, R.W., 143 100, 101, 135, 136

Guarino, L., 141 Keragaman somaklon, 79, 93-95, 97-100,

Gugur embrio, 63, 64 107

Keragaman. Lihat Keragaman somaklon Mix-Wagner, G., 140

Kimera (kimerik), 35, 37-40, 45, 90 Monoploid. Lihat Produksi tanaman haploid

Kinet, M., 145 Morel, G., 139

Kinetin, 10, 11, 13, 119, 121 Morfogenesis, 1, 5-14

Kolkisin, 50, 51, 75

Mosaik, 37, 94, 98 Kompatibilitas, 112, 114-116. Lihat juga Murashige, T., 139, 145 Inkompatibilitas Murphy, G., 142

Kompetensi, 2, 118 Mutagen, 35-41, 84,-92, 99, Kompetisi, 38, 75, 76, 126 Mutagen fisik, 36, 86, 91 Kreopresevasi, 33, 34, 101-110 Mutagen kimiawi, 37, 85-90 Kultur antera, 2-4, 45, 46, 49, 60, 137 Mutagenesis in vitro, 37, 85-92

Kultur embrio, 3, 4, 61-64 Mutagenesis. Lihat Mutagenesis in vitro

Kultur jaringan tanaman, 1-4, 14, 25, 30, Mutasi, 4, 35, 37-41, 85, 92, 95, 132, 133.

62, 93, 98 Lihat juga Mutagenesis in vitro;

Kultur kalus, 1, 3, 79, 81, 83, 95. 98. 99, 118 Keragaman somaklon Kultur meristem, 3, 27, 31, 111, 125

Kultur organ, 3 Nadgauda, R.S., 145

Kultur protoplas, 1-3, 74, 75, 80, 87, 90, 91, Nahri, M.H., 146

95, 99 Negrutiu, I., 143

Kultur sel tunggal, 3, 40, 65 Netron, 35, 86, 87 Kultur suspensi sel, 3, 74, 95, 99 Newton, A.C., 146

Kumar, A., 143 Nichterlein, K., 143

Kumar, P.P., 140, 143, 146 Niemi K.J., 144

Nitsch, C., 140 Larkin, P.J., 142, 143 Nitsch, J.P., 139, 141 Lawrence, P.E., 146 Nobecourt, P., 139

Lejeune, P., 144, 145 Nuclear magnetic resonance (NMR), 108 Lektin, 56

Levy, D., 145 Obuchi, S., 142

Liljegren, S.J., 143 Organisme yang dimodifikasi secara

Loo, A.H.B., 146 genetik (GMO), 81, 129

Organogenesis langsung, 39

Ma, H., 143 Organogenesis, 5, 20, 64, 97. Lihat juga

Maene, L.J., 140 Morfogenesis

Maheshwari, P., 141

Maheshwari, S.C., 139, 141 Paul, S., 146

Maliga, P., 142 Pehu, E., 146

Maluszynski, M., 143 Pektin, 68, 69 Mapes, M.O., 139 Pelletier, G., 139

Martiensen, R., 143 Pembekuan untuk penyimpanan, 34, 102-110

Marton, L., 142 Lihat juga Kreopreservasi

Mascarenhas, A.F., 145 Pembuahan in vitro, 55-64. Lihat juga

Matsuda, Y., 142 Penyerbukan

McClintock, Barbara, 143 Pembungaan in vitro, 117-124

Mears, K., 139 Pemuliaan barley, 135

Meyerowitz, E.M., 143, 145 Pemuliaan molekuler, 129-138 Microsatelites, 130 Penanda molekuler, 129-138 Mikropropagasi, 15-41, 79, 100, 125

Pengukuran pertumbuhan, 7

Miller, C.O., 139, 140 Pengumbian in vitro, 125-128 Penyambungan in vitro, 31, 111-116 Roberts, L.W., 142

Penyelamatan embrio, 58, 61, 63, 64, 77 Robinson, D., 145 Penyerbukan in vitro, 55-64 Rodriguez, F.I., 143 Penyimpanan plasma nutfah, 26, 32-34 Romero, J.M., 142 Perilleux, C., 144 Rowley, M.P., 145

Perkecambahan, 17, 44, 59, 60, 63, 64, 70, Rumah kaca, 15, 16, 24, 111, 112

134 Russel, J.R., 145

Perkembangan, definisi, 5

Pertumbuhan, definisi, 5 Sachs, R.M., 145

Petitjean, A., 145 Saghai-Maroof, M.A., 146 Petunia, 16, 26, 71, 80, 97

Silang balik dipercepat, 133-135

Phloem, 6, 12, 13, 114 Sambung mikro, 111-116

Pierik, R.L.M., 141 Sambung mikro secara in vitro. Lihat

Pohon buah-buahan tropis, Sambung mikro mikropropagasi komersial, 29, 30

Sambung pucuk, 112

Polimorfisme, 130, 131, 134-138 Savidge, B., 143

Poligonum, 55 Saw, L.G., 146

Polymerase chain reaction (PCR), 100, 131, Sayuran, mikropropagasi komersial, 15,

132, 134, 137 26, 29

Powell, W., 145, 146 Schaefer, G.W., 142 Prakash, A.P., 143 Schafer-Menuhr, A., 140

Prakash, N., 141 Schaller, G.E., 143 Prasharami, V.A., 145 Schell, J., 187

Produksi hibrid, 59, 75 Schumacher, H.M., 140 Produksi umbi mikro, 125-128. Lihat juga Scowcroft, W.R., 142, 143

Pengumbian in vitro Seabrook, J.E.A., 145 Protoplas, 1-3, 51, 64-78, 80, 81, 87, 90, 91, Seleksi dengan bantuan penanda, 133, 137

95, 99, 108 Semigamy, 45

Pucuk adventif, 21, 39, 46, 91

Senyawa fenol, 18-20, 113, 115 Serbuk sari, 45-53, 55-61, 102, 106

Quantitative trait loci (QTL), 133, 134, 136 Seymour, G.B., 144 Sharpe, F.T., 142

Radiasi, 36, 76, 86, 87. Lihat juga iradiasi Short tandem repeats (STR), 130 Radiasi UV, 86, 87 Sibridisasi, 76

Rajaseger, G., 146 Sidik jari genetik, 133, 135 Ramanatha, R., 141

Silang-balik, 133-135, 137

Ramsay, L., 146 Sinar gamma, 35, 86, 87, 90

Random Amplified Polymorphic DNA Sinar X, 45, 76, 86, 87, 90

(RAPD), 100, 130, 131, 135, 136 Sistem Sorba Rod, 113

Rangaswamy, N.S., 141 Sitokinin, 1, 2, 10-13, 17, 20, 21, 23-25, 49, Razdan, M.K., 141 95, 112, 117-120, 124, 126

Read, P.E., 140 Skoog, F., 139, 140, 145 Reaksi hipersensitivitas, 18 Smith, H.H., 142

Reid, D.M., 140 Smith, R.H., 141