• Tidak ada hasil yang ditemukan

Headache Therapy

Dalam dokumen Chronic Pain (Halaman 185-191)

Special Groups

2. ASSESSMENT

3.1. Headache Therapy

Both nonpharmacological and pharmacological therapies can effectively manage chronic headaches in children and adolescents (Table 3). Relaxation, stress management, and biofeedback are effective nonpharmacological head-ache therapies in pediatric patients (39,40). Analgesics and triptans are also effective in pediatric patients, although dose adjustments are needed (41–44).

Generally, triptans are administered at approximately half of the starting adult dose in adolescents. Orally disintegrating triptans may be particularly useful in children. Preventive therapy with antidepressants and antiepileptics is also ef-fective in children (44–48). Controlled trials have not evaluated selective sero-tonin reuptake inhibitors (SSRIs) for migraine prevention in pediatric patients.

Anecdotally, SSRIs may be effective and are generally better tolerated, with fewer cognitive effects, than other antidepressants.

4. SUMMARY

Common pain syndromes in children and adolescents include musculoskel-etal pain, headache, stomach ache, and chest pain. In general, increased overall prevalence and a female predominance develop once children reach adolescence.

Table 3

Migraine Treatments With Proven Efficacy in Pediatric Migraine Pharmacological therapies

Nonpharmacological therapies Acute care Prevention

Relaxation plus stress management Ibuprofen Antidepressants Amitriptyline Trazadone

Biofeedback Triptans Antiepileptics

Sumatriptan Valproate Zolmitriptan Topiramate Rizatriptan

Based on ref. 38.

with pain should be minimized by requiring school attendance, as well as partici-pation in physical education programs, unless significant structural pathology precludes specific activities. Psychosocial factors, including changes in family and school stress, are significant aggravating factors for pediatric pain and need to be identified and openly addressed as part of the treatment plan.

REFERENCES

1. Bruusgaard D, Smedbråten BK, Natvig B. Bodily pain, sleep problems and men-tal distress in schoolchildren. Acta Paediatr 2000; 89:597–600.

2. Campo JV, Comer DM, Jansen-McWilliams L, Gardner W, Kelleher KJ. Recur-rent pain, emotional distress, and health service use in childhood. J Ped 2002;

141:76–83.

3. Mikkelsson M, Salminen JJ, Kautiainen H. Non-specific musculoskeletal pain in preadolescents. Prevalance and 1-year persistence. Pain 1997; 73:29–35.

4. Grøholt E, Stigum H, Nordhagen R, Köhler L. Recurrent pain in children, socio-economic factors and accumulation in families. Eur J Epidemiol 2003; 18:965–975.

5. Petersen S, Bergstrom E, Brulin C. High prevalence of tiredness and pain in young schoolchildren. Scand J Public Health 2003; 31:367–374.

6. De Inocencio J. Musculoskeletal pain in primary pediatric care: analysis of 1000 consecutive general pediatric clinic visits. Pediatrics 1998; 102:E63.

7. Taimela S, Kujala U, Salminen J, Viljanen T. The prevalence of low back pain among children and adolescents: a nationwide, cohort-based questionnaire survey in Finland. Spine 1997; 22:1132–1136.

8. Ozge A, Bugdayci R, Sasmaz T, et al. The sensitivity and specificity of the case definition criteria in diagnosis of headache: a school-based epidemiological study of 5562 children in Mersin. Cephalalgia 2003; 23:138–145.

9. Abu-Arafeh I, Russell G. Prevalence of headache and migraine in schoolchildren.

BMJ 1994; 309:765–769.

9a. Apley J. The child with abdominal pains. 2nd Ed. Oxford, UK: Blackwell Scien-tific; 1975.

10. Bode G, Brenner H, Adler G, Rothenbacher D. Recurrent abdominal pain in chil-dren. Evidence from a population-based study that social and familial factors play a major role but not Helicobacter pylori infection. J Psychosom Res 2003; 54:

417–421.

11. Boey CM, Yao SB. An epidemiological survey of recurrent abdominal pain in a rural Malay school. J Paediatr Child Health 1999; 35:303–305.

12. Walker LS, Lipani TA, Greene JW, et al. Recurrent abdominal pain: symptom subtypes based on the Rome II criteria for pediatric functional gastrointestinal disorders. J Pediatr Gastroenter 2004; 38:187–191.

13. Sillanpaa M, Piekkala P, Kero P. Prevalence of headache at preschool age in an unselected child population. Cephalalgia 1991; 11:239–242.

14. Campo JV, Di Lorenzo C, Chiappetta L, et al. Adult outcomes of pediatric recur-rent abdominal pain: do they just grow out of it? Pediatrics 2001; 108:e1.

15. Russell G, Abu-Arafeh I, Symon DN. Abdominal migraine: evidence for exist-ence and treatment options. Paediatr Drugs 2002; 4:1–8.

16. Weydert JA, Ball TM, Davis MF. Systemic review of treatments for recurrent abdominal pain. Pediatrics 2003; 111:e1–e11.

17. Jarrett M, Heitkemper M, Czyzewski DI, Shulman R. Recurrent abdominal pain in children: forerunner to adult irritable bowel syndrome? J Spec Pediatr Nurs 2003; 8:81–89.

18. Evangelista JK, Parsons M, Rennenburg AK. Chest pain in children: diagnosis through history and physical examination. J Ped Health Care 2000; 14:3–8.

19. Gastesi-Larranaga M, Fernandez Landaluce A, Mintegi Raso S, Vazquez Ronco M, Benito Fernandez J. Dolor torácico en urgencies de pediatría: un proceso habitualamente benigno. An Pediatr (Barc) 2003; 59:234–238.

20. Song K, Morton AA, Koch KD, Herring JA, Browne RH, Hanway JP. Chronic musculoskeletal pain in childhood. J Ped Orthop 1998; 18:576–581.

21. Burton LJ, Quinn B, Pratt-Cheney JL, Pourani M. Headache etiology in a pediat-ric emergency department. Pediatr Emerg Care 1997; 13:1–4.

22. Kan L, Nagelberg J, Maytal J. Headaches in a pediatric emergency department:

etiology, imaging, and treatment. Headache 2000; 40:25–29.

23. Shivpuri D, Rajesh MS, Jain D. Prevalence and characteristics of migraine among adolescents: a questionnaire survey. Indian Pediatr 2003; 40:665–669.

24. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders, 2nd Ed. Cephalalgia 2004;

24(Suppl 1):24–25.

25. Metsähonkala L, Sillanpää M, Tuominen J. Headache diary in the diagnosis of childhood migraine. Headache 1997; 37:240–244.

26. Laurell K, Larsson B, Eeg-Olofsson O. Headache in schoolchildren: agreement between different sources of information. Cephalalgia 2003; 23:420–428.

27. Stafstrom CE, Rostasy K, Minster A. The usefulness of children’s drawings in the diagnosis of headache. Pediatrics 2002; 109:460–472.

28. Stordal K, Nygaard EA, Bentsen B. Organic abnormalities in recurrent abdominal pain in children. Acta Paediatr 2001; 90:638–642.

29. Alfvén G. One hundred cases of recurrent abdominal pain in children: diagnostics procedures and criteria for a psychosomatic diagnosis. Acta Paediatr 2003; 92:

43–49.

30. Kaiser RS, Primavera JP. Failure to mourn as a possible contributory factor to headache onset in adolescence. Headache 1993; 33:69–72.

31. Anttila P, Metsähonkala L, Helenius H, Sillanpää M. Predisposing and provoking factors in childhood headache. Headache 2000; 40:351–356.

32. Kaiser R. Depression in adolescent headache patients. Headache 1992; 32:340–344.

36. Powers SW, Patton SR, Hommel KA, Hershey AD. Quality of life in paediatric migraine: characterization of age-related effects using PedsQL 4.0. Cephalalgia 2004; 24:120–127.

37. Eccleston C, Malleson PN, Clinch J, Connell H, Sourbut C. Chronic pain in ado-lescents: evaluation of a programme of interdisciplinary cognitive behaviour therapy. Arch Dis Child 2003; 88:881–885.

38. Marcus DA, Loder E. Migraine in female children and adolescents. In Migraine in Women. Loder E. Marcus DA (eds.) BC Decker, Ontario, 2004.

39. Sartory G, Muller B, Metsch J, Pothmann R. A comparison of psychological and pharmacological treatment of pediatric migraine. Behav Res Ther 1998; 36:

1155–1170.

40. Scharff L, Marcus D, Masek BJ. A controlled study of minimal-contact thermal biofeedback in children with migraine. J Pediatr Psychol 2002; 27:109–119.

41. Lewis DW, Kellstein D, Dahl G, et al. Children’s ibuprofen suspension for the acute treatment of pediatric migraine. Headache 2002; 42:780–786.

42. Hershey AD, Powers SW, LeCates S, Bentti AL. Effectiveness of nasal sumatrip-tan in 5- to 12-year-old children. Headache 2001; 41:693–697.

43. Linder SL, Dowson AJ. Zolmitriptan provides effective migraine relief in adoles-cents. Int J Clin Pract 2000; 54:466–469.

44. Winner P, Lewis D, Visser WH, et al. Rizatriptan 5 mg for the acute treatment of migraine in adolescents: a randomized, double-blind, placebo-controlled study.

Headache 2002; 42:49–55.

45. Battistella PA, Ruffilli R, Cernetti R, et al. A placebo-controlled crossover trial using trazadone in pediatric migraine. Headache 1993; 33:36–39.

46. Hershey AD, Powers SW, Bentti A, Degrauw T. Effectiveness of amitriptyline in the prophylactic management of childhood headache. Headache 2000; 40:539–549.

47. Serdaroglu G, Erhan E, Tekgul H, et al. Sodium valproate prophylaxis in child-hood migraine. Headache 2002; 42:819–822.

48. Hershey AD, Powers SW, Vockell AB, et al. Effectiveness of topiramate in the prevention of childhood headaches. Headache 2002; 42:810–818.

CME QUESTIONS—CHAPTER 11

1. Common pain syndromes in pediatrics include:

a. Musculoskeletal pain b. Headache

c. Abdominal pain d. Chest pain e. All of the above

2. Which of the following statements is true?

a. Most complaints of musculoskeletal pain should be considered growing pains.

b. Musculoskeletal pain reports in elementary school children usually persist for at least 1 year.

c. Musculoskeletal pain is usually endorsed to avoid unpleasant activities or homework.

d. None of the above.

3. Which statistic is/are true?

a. About 6% of all visits to a pediatric clinic are for complaints of musculoskel-etal pain.

b. About 10% of children have migraine headaches.

c. About 25% of children with recurrent abdominal pain will report chronic ab-dominal pain as an adult.

d. All of the above e. None of the above

4. Effective therapies for pediatric migraine include:

a. Relaxation therapy b. Acupuncture c. Ibuprofen d. A and C e. All of the above

185

From: Chronic Pain: A Primary Care Guide to Practical Management Edited by: D. A. Marcus © Humana Press, Totowa, NJ

pregnancy. Her pregnancy has been uncomplicated, except for a weight gain of 40 lb. Over the last 4 weeks, she reports a pain in her left thigh. Initially, this would only occur with prolonged sitting or riding in the car, or when waiting in exceptionally long lines in the store. Now she finds that she has nearly constant pain in her upper, outer thigh. Additionally, this painful area feels prickly when she touches it. This week, she has also noticed pain and tingling in her right thumb when she wakes up in the morning or scrubs the counters at her home.

Her mother told her that these are the symptoms of multiple sclerosis, just like in a character on the mother’s soap opera television show. A distraught and tearful Ms. Rogers shares her concerns with her primary care physician, who reassures her that pain, including compressive neuropathy, occurs in a signifi-cant number of women during pregnancy and that these symptoms usually go away after delivery.

* * *

New pain, neurological complaints, or both during pregnancy are accompa-nied by special concerns for patient and doctor, both of whom worry about the risks of testing and treatment to the fetus, as well as the effects of any new health problem on the ability of the new mother to care for her baby. Alter-ations in hormones, water distribution, and weight are all important factors in changing risk for pain from new and preexisting pain syndromes during nancy. Understanding typical changes in common problems during preg-nancy—such as headache, back pain, and compressive neuropathy—can allay fears and minimize the use of unnecessary testing.

KEY CHAPTER POINTS

• Pain complaints occur in the majority of pregnant women.

• The lower back is the most common pain location during pregnancy.

• Compressive neuropathies occur more commonly during pregnancy because of changes in water retention, weight, and posture; they include Bell’s palsy, carpal tunnel syndrome, and meralgia paresthetica.

• Premorbid headache, especially migraine, improves in the majority of women in early pregnancy. Headache does persist, however, throughout pregnancy for a significant minority of women.

• Persistent pain during pregnancy may require treatment with safe nonpharma-cologic and pharmanonpharma-cological therapies to minimize disability and the need to self-medicate.

Pregnancy is associated with increased risk for a variety of musculoskeletal and neuropathic pain complaints. In a prospective study of 200 pregnant women, investigators identified pain occurring during pregnancy in 166 (85%), with new pain beginning during pregnancy in 137 (70%) (1). The most com-mon body area affected by pain was the back, especially in the lumbar and sacral areas (Fig. 1). In addition to the development of new pain during preg-nancy, preexisting pain conditions—such as low back pain and headache—are also often modified during pregnancy.

In this chapter, several commonly occurring painful conditions that occur in pregnancy are reviewed. Evaluating and treating pain during pregnancy offers unique challenges because of concerns for the effects of testing and treatment interventions on the developing baby. Increased ability of the patient to iden-tify common, self-limited, pregnancy-related pain complaints reduces the need to perform unnecessary testing during pregnancy and helps distinguish atypi-cal conditions that may warrant additional evaluations.

Dalam dokumen Chronic Pain (Halaman 185-191)