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BAB 5 :KESIMPULAN DAN SARAN

5.2 Saran

5.2.1 Untuk penelitian selanjutnya

 Perlu dilakukan penelitian lebih lanjut dan mendalam untuk melihat hubungan antara batu empedu dengan faktor 4F (Fourty,

Female,Fertile Fat)

 Melakukan penelitian dalam sebaran lebih luas lagi, dengan pengambilan sampel lebih banyak sehingga dapat menggambarkan faktor resiko batu empedu di Indonesia

5.2.2 Untuk RSUP Fatmawati

 Agar meningkatkan perhatian khusus pada pasien wanita, usia diatas 40 yang memiliki perawakan gemuk terhadap kejadian penyakit batu empedu

DAFTAR PUSTAKA

1. Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: Cholelithiasis and Cancer. Gut Liver. 2012;6(2):172–87. [PMC free article] [PubMed] 2. Berghofer A, Pischon T, Reinhold T, Apovian CM, Sharma AM, Willich SN.

Obesity prevalence from a European perspective: a systematic review. BMC Public Health 2008; 8:200.

3. Sudoyo, Aru W, dkk. 2009. Buku Ajar Ilmu Penyakit Dalam Jilid 1 Edisi V.Jakarta: EGC

4. Berghofer A, Pischon T, Reinhold T, Apovian CM, Sharma AM, Willich SN. Obesity prevalence from a European perspective: a systematic review. BMC Public Health 2008; 8:200.

5. Cetta, Francesco. 2014. Classification, Composition and Structure of Gallstones. Relevance of these Parameters for Clinical Presentation and Treatment. Biliary Lithiasis pp 51-65

6. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010; 303(3):235-41.

7. Sudoyo, Aru W, dkk. 2009. Buku Ajar Ilmu Penyakit Dalam Jilid III edisi V. Jakarta: EGC

8. Heshka.S, Heymsfield.S. 2001. Obesity and gallstones. Roosevelt Hospital Center, New York, USA

9. Getachew,Assefa. 2008. Epidemiology of gallstone disease in Gondar University

Hospital, as seen in the department of radiology.Ethiop.J.Health Dev. ;22(2) 10. Bertomeu A, Ros E, Zambon D, Vela M, Pérez-Ayuso RM, Targarona E, et

al. Apolipoprotein E polymorphism and gallstones. Gastroenterology. 1996;111:1603–10. [PubMed]

11. Redinger, Richard N. MD. 2007. The Pathophysilogy of Obesity and Its Clinical Manifestasion. Vol.3, Issues 11. Department of Medicine at the University of Louisville [PubMed]

12. Radmard, Amir Reza dkk. 2015. Gallstone disease and obesity : a population based study on abdominal fat distribution and gender differences. Annals Hepatology

13. Moghaddam, Alireza Ansari, Khorram,Alireza dkk.2015. The prevalence and Risk Factors of Gallstone Among Adults in South-East of Iran: A Population-Based Study. Vol.8, No.4. Global Journal of Health Science

14. Gray‟s Anatomy : Anatomy of the Human Body. Elsevier :2014. 18. Putz, Reinhard.

15. Sjamsuhidajat, R., dkk. 2016. Buku Ajar Ilmu Bedah-de Jong. Jakarta: EGC 16. Sherwood, Lauralee.2011. Fisiologi Manusia Dari Sel ke Sistem, Edisi VI.

Penerbit buku kedokteran EGC. Jakarta.

17. Dooley JS. Sherlock‟s Disease of the Liver and Biliary System. 12th ed. British: Wiley-Blackwell Publishing; 2011

18. [7] Acalovschi M. Cholesterol gallstones: From epidemiology to prevention. Postgrad Med J. 2001;77:221–9. [PMC free article] [PubMed]

19. Everson GT, McKinley C, Kern F., Jr. 1991. Mechanisms of gallstone formation in women. Effects of exogenous estrogen (Premarin) and dietary cholesterol on hepatic lipid metabolism. J Clin Invest.

20. Njeze, Gabriel E. 2013. Gallstones [PubMed] 19(2): 49-55

21. Cetta, Francesco. 2014. Classification, Composition and Structure of Gallstones. Relevance of these Parameters for Clinical Presentation and Treatment. Biliary Lithiasis pp 51-65

22. Lammert F, Matern S. The genetic background of cholesterol gallstone formation: an inventory of human lithogenic genes. Curr Drug Targets Immune Endocr Metabol Disord.

23. Epercum, Karel Johannes Van. 2011. Pathogenesis of cholesterol and pigment gallstones: An update. 35,281-287. Elsevier Masson.

24. Dooley JS. Sherlock‟s Disease of the Liver and Biliary System. 12th ed. British: Wiley-Blackwell Publishing; 2011

25. Hassler, Kenneth R., Jones, W. Mark. 2017. Gallbladder, Chocystectomy, Laparoscopic. 20/10/2017 [PubMed]

26. Halldestam I, Enell EL, Kullman E, Borch K. Development of symptoms and complications in individuals with asymptomatic gallstones. Br J Surg. 2004;91:734–8. [PubMed]

27. Parigi, Angelo Del, M.D. 2010. Definitions and Classification of Obesity. [PubMed]

28. Offei.F. 2005. Obesity – A preventable Diesease. Volume 39, number 3. Graha Medical Journal

29. Nguyen, Dang M. , El-serag, Hashem B. 2010. The Epidemiology of Obesity. 39(1): 1-7. National Institute of Health (NIH)

30. Mitchell, Nia MD,Catenacci, Vicki MD, dkk. 2011. Obesity : Overview of An Epidemic. 34(4):717-732. National Institutes of Health (NIH)

31. Redinger, Richard N. MD. 2007. The Pathophysilogy of Obesity and Its Clinical Manifestasion. Vol.3, Issues 11. Department of Medicine at the University of Louisville [PubMed]

32. Kharga,Bikram, Sharma,Barun Kumar, dkk. 2016. Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increase as a Function of BMI. [PubMed] 33. Artikel Khazanah Islam. 2015. 10 hadist tentang kesehatan dan kebersihan.

www.muslimdaily.net 03/11/17

34. Tuasikal, Muhammad Abduh,Msc. 2012. Hidup Sehat dengan Mengamalkan Sunnah. Muslim.or.id 03/11/17

LAMPIRAN 1

a. Jadwal Penelitian

No Kegiatan 1 2 3 BULAN KE- 4 5 6 7

1 Pengajuan Izin √ √ √ 2 Pembuatan Proposal Penelitian √ √ √ 3 Presentasi Persiapan Penelitian di RSUP Fatmawati √ 4 Pengambilan Data √ 5 Pengolahan dan Analisis Data √ 6 Pembuatan Laporan √ 7 Publikasi Laporan penelitian b. Anggaran Penelitian

No Keterangan Total Biaya

1 Biaya Adminstratif RS 1.000.000

2 Biaya Pengambilan Rekam Medis

90.000

3 Biaya tak terduga (transport, fotokopi/print, dan lainnya)

1.000.000

LAMPIRAN 3

Hasil Analisis Data

1. Grafik gambaran pasien batu empedu di RSUP Fatmawati 2015-2016

Usia

LAKI LAKI 28% PEREMPUAN 72%

Jenis Kelamin

15 - 19 1% 20 - 24 3% 25 - 29 2% 30 - 34 5% 35 - 39 14% 40 - 44 15% 45 - 49 22% 50 - 54 9% 55 - 59 12% 60 - 64 14% 65 - 69 3%

2. Gambaran status gizi dan tabel mean IMT pada penderita batu empedu Normoweight 18% Overweight 26% Underweight 9% Obes I 31% Obes II 16%

STATUS GIZI

Gender * StatusGizi Crosstabulation

StatusGizi

Total under normo over obes 1 obes 2

Gender laki laki 2 6 6 9 2 25

perempuan 6 11 18 20 13 68

Total 8 17 24 29 15 93

Mean IMT,BB, TB

N Range Minimum Maximum Mean Std. Deviation Variance Statistic Statistic Statistic Statistic Statistic Std. Error Statistic Statistic

IMT 93 23,28 15,78 39,06 25,6166 ,53896 5,19758 27,015

BB 93 72,00 38,00 110,00 64,8548 1,43107 13,80071 190,460

TB 93 47,00 140,00 187,00 159,2043 ,86846 8,37512 70,143

Mean IMT dan Usia Perempuan

N Range Minimum Maximum Mean Std. Deviation Variance Statistic Statistic Statistic Statistic Statistic Std. Error Statistic Statistic

IMT 68 22,53 16,53 39,06 25,9635 ,64946 5,35561 28,683

usia 68 46,00 19,00 65,00 47,5000 1,34395 11,08246 122,821 Valid N (listwise) 68

Mean IMT dan Usia Laki - laki

N Range Minimum Maximum Mean Std. Deviation Variance Statistic Statistic Statistic Statistic Statistic Std. Error Statistic Statistic

IMT 25 21,41 15,78 37,19 24,6976 ,94876 4,74379 22,504

usia 25 37,00 28,00 65,00 45,2800 2,14982 10,74911 115,543 Valid N (listwise) 25

LAMPIRAN 4

DAFTAR RIWAYAT HIDUP

DATA PRIBADI

Nama : Regi Azistha Amri

Jenis Kelamin : Laki Laki

Tempat Tanggal Lahir : Jakarta, 15 Juni 1996

Status : Belum menikah

Agama : Islam

Alamat : Jalan Taman AA, No. 7AA RT 10/05 Pos pongumben Kebon Jeruk Jakarta Barat 11560

Nomor Telepon : 082298091559

Email : regizsth@gmail.com

RIWAYAT PENDIDIKAN

1) Tahun 2002 – 2008 : SD Islam Al Azhar 5 Kemandoran 2) Tahun 2008 – 2011 : SMPN 75 Jakarta

3) Tahun 2011 – 2014 : SMAN 47 Jakarta

4) Tahun 2014 – Sekarang : Program studi Kedokteran dan Profesi Dokter UIN Syarif Hidayatulla Jakarta

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