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BAB V KESIMPULAN DAN SARAN

B. Saran

1. Perlu adanya optimasi lebih lanjut terkait formulasi multiemulsi supaya sediaan yang dihasilkan bisa lebih optimum.

2. Perlu adanya pertimbangan penggunaan ukuran FDC yang lebih besar untuk mengurangi variabel tak terkendali yaitu ketebalan membran.

3. Perlu adanya penelitian penetrasi lebih lanjut dengan menggunakan kulit hewan uji lainnya (misalnya kulit telinga babi) atau kulit manusia, supaya dapat menggambarkan penetrasi yang sebenarnya

4. Perlu adanya pembanding dengan zat yang telah diketahui penetrasi dan efeknya

5. Perlu adanya uji kebocoran FDC dan uji TEER sebelum dilakukan penetrasi dengan FDC.

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Lampiran 1. Spektrum antosianin pada ekstrak metanol kelopak bunga rosella (Hibiscus sabdariffa L.)

Lampiran 2. Penetapan bobot tetap ekstrak metanol kelopak bunga rosella

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