BAB VII SIMPULAN DAN SARAN
7.2 Saran
7.2.1 Perlu dilakuan penelitian lebih lanjut tentang efek samping pemberian kombinasi hormon estrogen, progesteron dan testosteron jangka panjang.
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Lampiran 8
HASIL STUDI PENDAHULUAN
Rerata Ketebalan Jaringan Epitel Vagina pada Kelima Kelompok Tikus Percobaan
Kelompok Rerata Ketebalan Jaringan Epitel Vagina
Standar Deviasi Kontrol 4,24 μm 0,49 EP1 27,54 μm 0,056 EPT 1 13,66 μm 0,11 EP2 42,97 μm 0,63 EPT2 31,35 μm 1,93
Rerata Luas Area Jaringan Muskularis (Otot Polos) Vagina pada Kelima Kelompok Tikus Percobaan
Kelompok Rerata Luas Area Jaringan Muskularis
(Otot Polos) Vagina
Standar Deviasi Kontrol 7,7079 % 0,59 EP1 15,77 % 3,11 EPT 1 20,1952 % 0,45 EP2 16,1483 % 1,72 EPT2 38,1882 % 7,16
Rerata Jumlah Pembuluh Darah Vagina pada Kelima Kelompok Tikus Percobaan
Kelompok Rerata Jumlah Pembuluh Darah Vagina Standar Deviasi Kontrol 2 0,70 EP1 4 0,70 EPT 1 3 1,41 EP2 4 0,70 EPT2 6 1,41
HASIL PEMERIKSAAN HISTOPATOLOGI
Penampang melintang dinding vagina Rattus norvegicus (Perbesaran 100x) Kelompok kontrol post ovariectomy
Penampang melintang dinding vagina Rattus norvegicus (Perbesaran 100x) Kelompok Perlakuan : Estrogen 5μg/day dan Progesteron 300 μg/day selama 30
Penampang melintang dinding vagina Rattus norvegicus (Perbesaran 100x) Kelompok Perlakuan : Estrogen 5μg/day + Progesteron 300 μg/day + Testosteron
11 μg/day selama 30 hari
Penampang melintang dinding vagina Rattus norvegicus (Perbesaran 100x) Kelompok Perlakuan : Estrogen 11 μg/day + Progesteron 180 μg/day selama 30
Penampang melintang dinding vagina Rattus norvegicus (Perbesaran 100x) Kelompok Perlakuan : Estrogen 11 μg/day + Progesteron 180 μg/day +