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'I'hesi s Subr.d tted by No. 391 for the Animal F.u sbc:::.r:dry Section of the M.Agr.Sc. Examination, 1946
INTf0DUCTIJN
MH.TJMY J.i THt; TJYhOID GLJ-J:D Review of Li ter.:. tlJ re
Genersl �natomy of the Thyroid Gl��d
The reight of the Thyroid Glcnd in C�ttle
t1r;;thods Results
f�v�e� o� Liter�tcre
feL.tior :Jf Ioc.irc to L:e T>::roid Glu:d Regulc:. ti or� of Th�·roi d ,.c ti v l t.�
}�ysiolo�icLlly Active Iodi��tod Proteins
(a) Discove:ri
(b) PhJ.r3i ologi cc.:.l Effects of J,rti fi d::..l
Psge
1 4
4 5
8
9
1 5
1 5 1 �)
17
17
Th:'roproteins 18
ExJerimentc.:.l 20
Potency of Thyro�r�tcin 21
General and Histological Technique 25
.Measurement of the Height of t�e Epi theli<::l Cells 29
Effects of Thyroprotein
(a) General Effects
�b) I Effects on Acina- Cel l Height and Thyroid Gland ·Weight
38 38
Review of Literature on Goitrogeric Subst�nces Natu r� of Goitrogenic SubstE.nces
Mode of Action of GoitrogEnic Subst&rces To:xic Effect of GGitrogenic Substc_r_ces Ex;:erirnen tc..l
DISCLJ-:)0101�
Effects of Thioure� or D�iry Co�s
(b) c��erLl Effect�
le) F�frct on Ac5nar Cell ?eigtt ��d Th:/roid ':',·eicht
Page
42
44
46
48 48
51 5.3 t1